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作者:Vercammen, Ans; Wray, Britt; Crider, Yoshika S.; Belkin, Gary; Lawrance, Emma L.
作者单位:Curtin University; University of Queensland; Stanford Medicine; Stanford University; University of California System; University of California Berkeley; Stanford University; Columbia University; New York University; Imperial College London; Imperial College London
摘要:Awareness of the threats of climate change is causing distress in increasingly documented ways, with youth particularly affected. Experiences such as climate distress and eco-anxiety have implications for the health and well-being of societies and economies, including individuals' mental health and future planning, as well as their agency beliefs. Here, we show in a large sample of US youth (n = 2,834, ages 16 to 24) that the majority of US youth experience moderate climate distress and some f...
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作者:Kohler, Timothy A.; Bogaard, Amy; Ortman, Scott G.
作者单位:Washington State University; The Santa Fe Institute; University of Oxford; University of Colorado System; University of Colorado Boulder
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作者:Wang, Xingliang; Yue, Yujin; Zhai, Yuqian; Wang, Falong; Zhuang, Xuna; Wu, Shuwen; Yang, Yihua; Tabashnik, Bruce E.; Wu, Yidong
作者单位:Nanjing Agricultural University; University of Arizona
摘要:Crops genetically engineered to produce insecticidal proteins from the bacterium Bacillus thuringiensis (Bt) have been used extensively to control some major crop pests, but their benefits decrease when pests evolve resistance. Better understanding of the genetic basis of resistance is needed to effectively monitor, manage, and counter pest resistance to Bt crops. Resistance to Bt proteins in at least 11 species of Lepidoptera, including many important crop pests, is associated with naturally ...
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作者:Gasparin, Matteo; Wang, Ruodu; Ramdas, Aaditya
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作者:Ishimoto, Naito; Wong, Joshua L. C.; He, Shan; Shirran, Sally; Wright-Paramio, Olivia; Seddon, Chloe; Singh, Nanki; Balsalobre, Carlos; Sonani, Ravi R.; Clements, Abigail; Egelman, Edward H.; Frankel, Gad; Beis, Konstantinos
作者单位:UK Research & Innovation (UKRI); Science & Technology Facilities Council (STFC); STFC Rutherford Appleton Laboratory; Imperial College London; University of St Andrews; University of Barcelona; University of Virginia; University of Virginia (UVA) Health System
摘要:Conjugation, the major driver of the spread of antimicrobial resistance genes, relies on a conjugation pilus for DNA transfer. Conjugative pili, such as the F-pilus, are dynamic tubular structures, composed of a polymerized pilin, that mediate the initial donor-recipient interactions, a process known as mating pair formation (MPF). IncH are low-copy-number plasmids, traditionally considered broad host range, which are found in bacteria infecting both humans and animals. The reference IncHI1 pl...
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作者:Campbell, Erin E.; Sehyr, Zed Sevcikova; Pontecorvo, Elana; Cohen-Goldberg, Ariel; Emmorey, Karen; Caselli, Naomi
作者单位:Boston University; Chapman University System; Chapman University; Tufts University; California State University System; San Diego State University
摘要:The view that words are arbitrary is a foundational assumption about language, used to set human languages apart from nonhuman communication. We present here a study of the alignment between the semantic and phonological structure (systematicity) of and Spanish. Across all three languages, words that are semantically related are more likely to be phonologically related, highlighting systematic alignment between word form and word meaning. Critically, there is a significant effect of iconicity ...
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作者:Koyanagi, Naoto; Hengphasatporn, Kowit; Kato, Akihisa; Nobe, Moeka; Takeshima, Kosuke; Maruzuru, Yuhei; Maenaka, Katsumi; Shigeta, Yasuteru; Kawaguchi, Yasushi
作者单位:University of Tokyo; University of Tokyo; University of Tokyo; University of Tsukuba; Hokkaido University; Hokkaido University; University of Tokyo
摘要:Herpesviruses encode conserved protein kinases (CHPKs) that target dependent kinase (CDK) phosphorylation sites; thus, they are termed kinases. Tyrosine 15 in the GxGxxG motifs of CDK1 and CDK2, whose tion down-regulates their catalytic activities, is conserved in the corresponding CHPKs. We found that CHPK UL13, the corresponding Tyr-162 in virus 2 (HSV-2), was phosphorylated in HSV-2-infected cells. Mutational HSV-2 UL13 Tyr-162 suggested that phosphorylation of UL13 Tyr-162 phosphorylation ...
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作者:Li, Zhuowei; Paitandi, Rajendra Prasad; Tsutsui, Yusuke; Matsuda, Wakana; Nobuoka, Masaki; Chen, Bin; Ghosh, Samrat; Tanaka, Takayuki; Suda, Masayuki; Zhu, Tong; Kageyama, Hiroshi; Miyake, Yoshihiro; Shinokubo, Hiroshi; Takagi, Makito; Shimazaki, Tomomi; Tachikawa, Masanori; Suzuki, Katsuaki; Kaji, Hironori; Ando, Yasunobu; Ezaki, Takahiro; Seki, Shu
作者单位:Kyoto University; Kyoto University; Nagoya University; Yokohama City University; Kyoto University; University of Tokyo
摘要:Mimicking the interconvertible carbon allotropes of 2-dimensional (2D) graphene and 1-dimensional (1D) carbon nanotubes (CNTs), herein we report the in situ transformation of 2D it-conjugated covalent organic frameworks (COFs) sheet into 1D nanotubular structures via self-assembly the sheets at solvent interfaces. The facile roll-sheets self-assembly resulted in coaxial nanotubes with uniform cross-sectional diameter, which was realized for diazapyrene-based COFs but not for the corresponding ...
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作者:Maxwell, M. Willow H.; Causier, Barry E.; Chippendale, Jasper; Ault, James R.; Bell, Chris A.
作者单位:University of Leeds; University of Leeds
摘要:Crop pathogens often lack exclusive access to their host and must interact with plants concurrently engaged with numerous other symbionts. Here, we demonstrate that the colonization of hosts by plant-mutualistic mycorrhizal fungi can indirectly induce transcriptional responses of a major plant parasite, the nematode Globodera pallida, via a modified host resource profile. A shift in the resource profile of the root, where the parasite feeds, is perceived and responded to by the parasite throug...
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作者:Zeng, Xiao-Min; Berdugo, Miguel; Saez-Sandino, Tadeo; Tao, Dongxue; Ren, Tingting; Zhou, Guiyao; Liu, Yu-Rong; Terrer, Cesar; Reich, Peter B.; Delgado-Baquerizo, Manuel
作者单位:Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Instituto de Recursos Naturales y Agrobiologia de Sevilla (IRNAS); Huazhong Agricultural University; Chinese Academy of Sciences; Wuhan Botanical Garden, CAS; Complutense University of Madrid; Western Sydney University; Northeast Normal University - China; Nanjing Forestry University; Massachusetts Institute of Technology (MIT); University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; University of Minnesota System; University of Minnesota Twin Cities
摘要:Montane ecosystems are crucial for maintaining global biodiversity and function that sustain life on our planet. Yet, these ecosystems are highly vulnerable to changing temperatures and may undergo critical transitions under ongoing climate change. What we do not know is to what extent montane biodiversity and ecosystem services will respond to local temperature variations in a gradual versus abrupt manner across global environments. To fill this knowledge gap, we conducted a global synthesis,...