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作者:Alonso-Pauli, Eduard; Balart, Pau; Ezquerra, Lara; Hernandez-Arenaz, Inigo
作者单位:Universitat de les Illes Balears; Universidad Publica de Navarra; Universidad Publica de Navarra
摘要:Through a field study (N = 1,519) that uses a technology to record real-time data on waste sorting, we find that offering the opportunity to sign a pledge increases the effectiveness of an environmental campaign. With a timespan of over four years, the pledge increased waste sorting participation by 4.55 to 5.10 percentage points (SD = 0.1997). The effect is greater immediately after the campaign (around 9 to 10 pp during the first 15 wk), but it remains sizable and statistically significant 1...
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作者:Tang, Haitong; Zou, Yan; Zhang, Hai-Ning; Jin, Guo-Xin
作者单位:Fudan University; Nanjing University
摘要:Supported by chiral stationary phase high- performance liquid chromatography HPLC (CSP- HPLC), examples of chiral mechanically interlocked organic molecules, including knots, rotaxanes, and catenanes, have been reported. However, the exploration of stereoselective construction of chiral cationic complexes, particularly those induced by point chirality, has been notably limited due to the constraints posed by the type of chiral chromatographic columns and separation efficiency. To address this,...
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作者:Argyle, Lisa P.; Busby, Ethan C.; Cubler, Joshua R.; Lyman, Alex; Olcott, Justin; Pond, Jackson; Wingate, David
作者单位:Brigham Young University; Brigham Young University
摘要:Despite its importance to society and many decades of research, key questions about the social and psychological processes of political persuasion remain unanswered, often due to data limitations. We propose that AI tools, specifically generative large language models (LLMs), can be used to address these limitations, offering important advantages in the study of political persuasion. In two preregistered online survey experiments, we demonstrate the potential of generative AI as a tool to stud...
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作者:Higgins, Michael D.; Greene, Chris H.
作者单位:Purdue University System; Purdue University; Purdue University System; Purdue University
摘要:This work treats resonant collisions between five identical ultracold bosons in the framework of the adiabatic hyperspherical representation. The five-body recombination rate coefficient is quantified using a semiclassical description in conjunction with an analysis of the lowest five-body hyperspherical adiabatic potential curves in a scattering length regime with no universal weakly bound tetramers, trimers, or dimers. A comparison is made between these results and the only existing experime...
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作者:Morejon, Bianca; Michel, Kristin
作者单位:Kansas State University
摘要:Serine protease cascades regulate key innate immune responses. Their activation cleaves a series of inactive protease zymogens, which then activate downstream effector enzymes, ensuring a rapid response. In mosquitoes, these cascades involve clip-domain serine proteases and their noncatalytic homologs (CLIPs), whose make-up and structural organization are not fully understood. Here, we systematically assessed the contribution of individual CLIPs to humoral immunity in Anopheles gambiae, by per...
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作者:Sun, Qiu; Tian, Xiaowen; Tan, Lun; Deng, Yan; Liu, Sicen; Xiong, Yixiao; Feng, Yuying; Wang, Yujia; Zhang, Lele; Zhu, Jiayi; Xiao, Huan; Shao, Zhenhua; Guo, Yingqiang; Yan, Wei; Li, Tao; Ouyang, Liang
作者单位:Sichuan University; Sichuan University; Sichuan University; Sichuan University; Shanghai University; Tianfu Jincheng Laboratory; Sichuan University
摘要:Heart failure with preserved ejection fraction (HFpEF) represents a significant global health burden, yet effective pharmacotherapies remain elusive. The angiotensin-like 1 receptor, also known as the apelin receptor (APLNR), is a promising target for treating HFpEF due to its role in modulating cardiovascular function. Despite the cardioprotective effects of endogenous ligand, apelin, achieving G-protein-biased agonism for therapeutic benefit poses a significant challenge. In this study, we u...
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作者:Wu, Zhiwei; Wu, Xiaotong; Wang, Zhizhi; Ye, Xiqian; Pang, Lan; Wang, Yanping; Zhou, Yuenan; Chen, Ting; Zhou, Sicong; Wang, Zehua; Sheng, Yifeng; Zhang, Qichao; Chen, Jiani; Tang, Pu; Shen, Xingxing; Huang, Jianhua; Drezen, Jean- Michel; Strand, Michael R.; Chen, Xuexin
作者单位:Zhejiang University; Universite de Tours; University System of Georgia; University of Georgia
摘要:Animals often exhibit increased aggression in response to starvation, while parasites often manipulate host behavior. In contrast, underlying molecular mechanisms for these behavioral changes are mostly unknown. The diamondback moth, Plutella xylostella, is an agricultural pest that feeds on cruciferous plants as larvae, while Cotesia vestalis is a parasitoid wasp that parasitizes diamondback moth larvae. In this study, we determined that unparasitized diamondback moth larvae exhibit increased...
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作者:Chi, Guanghua; Abel, Guy J.; Johnston, Drew; Giraudy, Eugenia; Bailey, Mike
作者单位:University of Hong Kong; International Institute for Applied Systems Analysis (IIASA); Harvard University
摘要:Existing estimates of human migration are limited in their scope, reliability, and timeliness, prompting the United Nations and the Global Compact on Migration to call for improved data collection. Using privacy protected records from three billion Facebook users, we estimate country-to-country migration flows at monthly granularity for 181 countries, accounting for selection into Facebook usage. Our estimates closely match high-quality measures of migration where available but can be produced...
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作者:Cordero, Radames J. B.; de Groh, Kim K.; Dragotakes, Quigly; Singla, Saranshu; Maurer, Christopher; Trunek, Andrew; Chiu, Arlene; Hwang, Jonghyun; Crowell, Sylvie; Benyo, Theresa; Thon, Susanna M.; Rothschild, Lynn J.; Dhinojwala, Ali; Casadevall, Arturo
作者单位:Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health; National Aeronautics & Space Administration (NASA); NASA Glenn Research Center; University System of Ohio; University of Akron; Johns Hopkins University; Princeton University; Johns Hopkins University; National Aeronautics & Space Administration (NASA)
摘要:Materials in low Earth orbit (LEO) face radiation, atomic oxygen erosion, and extreme temperature fluctuations, which can severely compromise their structural and functional integrity. Developing lightweight, multifunctional materials capable of withstanding these harsh conditions is critical for long-term space exploration and sustainable extraterrestrial settlements. This study evaluates the structural stability and radiation shielding efficacy of polylactic acid (PLA) and biocomposites, inc...
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作者:Jo, Yeara; Greene, Trever T.; Chiale, Carolina; Zhang, Kai; Fang, Ziyan; Dallari, Simone; Marooki, Nuha; Wang, Wei; Zuniga, Elina I.
作者单位:University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego
摘要:Plasmacytoid Dendritic cells (pDCs) are the most potent producers of interferons, which are critical antiviral cytokines. pDC development is, however, compromised following a viral infection, and this phenomenon, as well as its relationship to conventional (c)DC development is still incompletely understood. By using lymphocytic choriomeningitis virus (LCMV) infection in mice as a model system, we observed that DC progenitors skewed away from pDC and toward cDC development during in vivo viral ...