18期

最新文章

• Late Cretaceous community structure changed before the asteroid AI翻译
  作者：Polly, P. David
  作者单位：University of Helsinki; Indiana University System; Indiana University Bloomington; Indiana University System; Indiana University Bloomington; Indiana University System; Indiana University Bloomington
• Distantly related bacteria share a rigid proteome allocation strategy with flexible enzyme kinetics AI翻译
  作者：Zhu, Manlu; Mori, Matteo; Hwa, Terence; Dai, Xiongfeng
  作者单位：Central China Normal University; University of California System; University of California San Diego
  摘要：Bacteria are known to allocate their proteomes according to how fast they grow, and the allocation strategies employed strongly affect bacterial adaptation to different environments. Much of what is currently known about proteome allocation is based on extensive studies of the model organism Escherichia coli. It is not clear how much of E. coli's proteome allocation strategy is applicable to other species, particularly since different species can grow at vastly different rates even in the same...
• Ultrasound- activated cilia for biofilm control in indwelling medical devices AI翻译
  作者：Amado, Pedro; Dillinger, Cornel; Bahou, Chaimae; Gheinani, Ali Hashemi; Obrist, Dominik; Burkhard, Fiona; Ahmed, Daniel; Clavica, Francesco
  作者单位：University of Bern; Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Bern; University Hospital of Bern; University of Bern; Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Harvard University; Harvard Medical School; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute
  摘要：Biofilm formation and encrustation are major issues in indwelling medical devices, such as urinary stents and catheters, as they lead to blockages and infections. Currently, to limit these effects, frequent replacements of these devices are necessary, resulting in a significant reduction in patients' quality of life and an increase in healthcare costs. To address these challenges, by leveraging recent advancements in robotics and microfluidic technologies, we envision a self-cleaning system fo...
• Historians use data science to mine the past AI翻译
  作者：Beans, Carolyn
• Possible evidence of excitonic condensation in a topological insulator AI翻译
  作者：Mori, Ryo; Takasan, Kazuaki; Ai, Ping; Ciocys, Samuel; Kawaguchi, Kaishu; Kondo, Takeshi; Morimoto, Takahiro; Lanzara, Alessandra
  作者单位：United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; University of California System; University of California Berkeley; University of Tokyo; University System of Maryland; University of Maryland College Park; University of Tokyo; University of Tokyo
  摘要：The transient excitonic condensate is a nonequilibrium electron-hole Bardeen- Cooper-Schrieffer state in a photoexcited semiconductor and semimetal, where electron-hole pairs undergo a phase transition and condense into a single coherent quantum state. Despite numerous experimental works to realize the predicted excitonic condensation phase, experimental evidence still remains elusive. This is largely due to the absence of direct measurements of a material's transient momentum-dependent electr...
• Stiffness-gradient adhesive structure with mushroom-shaped morphology via electrically activated one-step growth AI翻译
  作者：Wang, Duorui; Liu, Tianci; Tian, Hongmiao; Zhang, Jinyu; He, Qiguang; Li, Xiangming; Wang, Chunhui; Chen, Xiaoliang; Shao, Jinyou
  作者单位：Xi'an Jiaotong University; Xi'an Jiaotong University; Chinese University of Hong Kong; University of Pennsylvania
  摘要：Reptiles in nature have evolved excellent adhesion systems to adapt to complex natural environments, inspired by which high-performance bioinspired dry adhesives have been consistently created by precisely replicating the natural structures. Stiffness gradient, as a special feature evolved in reptilian adhesion systems, offers significant advantages in enhancing adhesion adaptation and stability.However, it remains a challenge to accurately replicate the geometrical morphology and soft-rigid c...
• Structural basis for substrate selectivity by site- one protease revealed by studies with a small- molecule inhibitor AI翻译
  作者：Bullington, Ashley, V; Micallo, Ilaria; Bajaj, Bilkish; Kumar, Pankaj; Schlamowitz, Netanya; Silva, Aurora; Hendrix, Sebastian; Zelcer, Noam; Kober, Daniel L.
  作者单位：University of Texas System; University of Texas Southwestern Medical Center; University of Amsterdam
  摘要：Site-one protease (S1P) carries out the first proteolytic step to activate membrane-bound effector proteins in the Golgi. S1P matures through an autocatalytic process that begins in the endoplasmic reticulum (ER) and culminates with the displacement of its inhibitory pro-domain by its cofactor, sterol regulatory element binding protein-regulating gene (SPRING). Spatial control of S1P activity and substrate localization underpins signaling pathways governing, among others, lipogenesis, ER stres...
• Exposing the role of individual heterogeneity in bighorn sheep population dynamics AI翻译
  作者：Forsythe, Amy B.
  作者单位：University of British Columbia; University of British Columbia
• Multiple sclerosis and gut microbiota: Lachnospiraceae from the ileum of MS twins trigger MS-like disease in germfree transgenic mice-An unbiased functional study AI翻译
  作者：Yoon, Hongsup; Gerdes, Lisa Ann; Beigel, Florian; Sun, Yihui; Koevilein, Janine; Wang, Jiancheng; Kuhlmann, Tanja; Flierl-Hecht, Andrea; Haller, Dirk; Hohlfeld, Reinhard; Baranzini, Sergio E.; Wekerle, Hartmut; Peters, Anneli
  作者单位：University of Munich; University of Munich; University of Munich; University of Munich; University of California System; University of California San Francisco; University of Munster; Technical University of Munich; Handong Global University
  摘要：We developed a two-tiered strategy aiming to identify gut bacteria functionally linked to the development of multiple sclerosis (MS). First, we compared gut microbial profiles in a cohort of 81 monozygotic twins discordant for MS. This approach allowed to minimize confounding effects by genetic and early environmental factors and identified over 50 differently abundant taxa with the majority of increased taxa within the Firmicutes. These included taxa previously described to be associated with...
• Unbalanced social-ecological acceleration led to state formation failure in early medieval Poland AI翻译
  作者：Izdebski, Adam; Czerwinski, Sambor; Jankowiak, Marek; Danielewski, Marcin; Fiolna, Sabina; Gromig, Raphael; Guzowski, Piotr; Haghipour, Negar; Hajdas, Irka; Kolaczek, Piotr; Lamentowicz, Mariusz; Marcisz, Katarzyna; Niebieszczanski, Jakub; Sankiewicz, Pawel; Wagner, Bernd
  作者单位：Max Planck Society; University of Warsaw; University of Warsaw; Fahrenheit Universities; University of Gdansk; Adam Mickiewicz University; Free University of Berlin; Simon Fraser University; University of Cologne; University of Bialystok; Swiss Federal Institutes of Technology Domain; ETH Zurich; Swiss Federal Institutes of Technology Domain; ETH Zurich; Adam Mickiewicz University
  摘要：Rapid social-ecological intensification is a recurrent feature of human history. It occurred in different forms and contexts; its outcomes may have been sustainable or transient. Until recently, such intensifications usually accompanied state formation: Consolidation of political power was often coupled with exponential increase in human exploitation of the environment of a given area. Here, we study one such case, uniquely well-documented through our rich paleoecological, archaeological, numi...