作者:Kim, David E.; Watson, Joseph L.; Juergens, David; Majumder, Sagardip; Sonigra, Ria; Gerben, Stacey R.; Kang, Alex; Bera, Asim K.; Li, Xinting; Baker, David
作者单位:University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; Howard Hughes Medical Institute
摘要:Francis Crick's global parameterization of coiled coil geometry has been widely useful for guiding design of new protein structures and functions. However, design guided by similar global parameterization of beta barrel structures has been less successful, likely due to the deviations from ideal barrel geometry required to maintain inter-strand hydrogen bonding without introducing backbone strain. Instead, beta barrels have been designed using two-dimensional structural blueprints; while this ...
作者:Slaughter, Isaac; Peytavin, Axel; Ugander, Johan; Saveski, Martin
作者单位:University of Washington; University of Washington Seattle; Stanford University; Yale University
摘要:Social networks scaffold the diffusion of information on social media. Much attention has been given to the spread of true vs. false content on online social platforms, including the structural differences between their diffusion patterns. However, much less is known about how platform interventions on false content alter the engagement with and diffusion of such content. In this work, we estimate the causal effects of Community Notes, a novel fact-checking feature adopted by X (formerly Twitt...