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作者：Enciso, Alberto; Kepplinger, Willi; Peralta-Salas, Daniel
作者单位：Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Instituto de Ciencias Matematicas (ICMAT); University of Vienna
摘要：We show that there exist closed three-dimensional Riemannian manifolds where the incompressible Euler equations exhibit smooth steady solutions that are isolated in the 1-topology. The proof of this fact combines ideas from dynamical systems, which appear naturally because these isolated states have strongly chaotic dynamics, with techniques from spectral geometry and contact topology, which can be effectively used to analyze the steady Euler equations on carefully chosen Riemannian manifolds....
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作者：Dai, Ruoyin; Yang, Shian; Pang, Tianxing; Tian, Mengyuan; Wang, Hao; Zhang, Dong; Wu, Yunfeng; Kondo, Hideki; Andika, Ida Bagus; Kang, Zhensheng; Sun, Liying
作者单位：Northwest A&F University - China; Northwest A&F University - China; Northwest A&F University - China; Northwest A&F University - China; Okayama University; Qingdao Agricultural University; Northwest A&F University - China
摘要：The presence of viruses that spread to both plant and fungal populations in nature has posed intriguingly scientific question. We found a negativestrand RNA virus related to members of the family Phenuiviridae, named Valsa mali negativestrand RNA virus 1 (VmNSRV1), which induced strong hypovirulence and was prevalent in a population of the phytopathogenic fungus of apple Valsa canker (Valsa mali) infecting apple orchards in the Shaanxi Province of China. Intriguingly, VmNSRV1 encodes a protein...
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作者：Sadhu, Raj Kumar; Lucianob, Marine; Xi, Wang; Martinez-Torres, Cristina; Schroeder, Marcel; Blum, Christoph; Tarantola, Marco; Villa, Stefano; Penic, Samo; Iglic, Ales; Betae, Carsten; Steinbock, Oliver; Bodenschatz, Eberhard; Ladoux, Benoit; Gabriele, Sylvain; Gov, Nir S.
作者单位：Weizmann Institute of Science; University of Geneva; University of Mons; Centre National de la Recherche Scientifique (CNRS); Universite Paris Cite; University of Potsdam; Max Planck Society; University of Ljubljana; Kanazawa University; State University System of Florida; Florida State University; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Chemistry (INC); Universite PSL; UNICANCER; Institut Curie; Sorbonne Universite
摘要：Cells often migrate on curved surfaces inside the body, such as curved tissues, blood vessels, or highly curved protrusions of other cells. Recent in vitro experiments provide clear evidence that motile cells are affected by the curvature of the substrate on which they migrate, preferring certain curvatures to others, termed curvotaxis. The origin and underlying mechanism that gives rise to this curvature sensitivity are not well understood. Here, we employ a minimal cell model which is compos...
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作者：Sinclair, Alyssa H.; Wang, Yuxi C.; Adcock, R. Alison
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作者：Kokalja, Jure
作者单位：Slovenian Academy of Sciences & Arts (SASA); Jozef Stefan Institute; University of Ljubljana
摘要：The bad metallic phase with resistivity above the Mott-Ioffe-Regel (MIR) limit, which appears also in cuprate superconductors, was recently understood by cold atom and computer simulations of the Hubbard model via charge susceptibility and charge diffusion constant. However, since reliable simulations can be typically done only at temperatures above the experimental temperatures, the question for cuprate superconductors is still open. This paper addresses this question by resorting to heat tra...
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作者：Shi, Yanan; Morgan, Jason P.
作者单位：Southern University of Science & Technology
摘要：Delamination of the continental lithospheric mantle is well recorded beneath several continents. However, the fate of the removed continental lithosphere has been rarely noted, unlike subducted slabs reasonably well imaged in the upper and mid mantle. Beneath former Gondwana, recent seismic tomographic models indicate the presence of at least 5 horizontal fast- wavespeed anomalies at -600 km depths that do not appear to be related to slab subduction, including fast structures in locations cons...
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作者：Silberstein, John L.; Du, Jasper; Chan, Kun-Wei; Frank, Jessica A.; Mathews, Irimpan I.; Kim, Yong Bin; You, Jia; Lu, Qiao; Liu, Jia; Philips, Elliot A.; Liu, Phillip; Rao, Eric; Fernandez, Daniel; Rodriguez, Grayson E.; Kong, Xiang-Peng; Wang, Jun; Cochran, Jennifer R.
作者单位：Stanford University; Stanford University; New York University; New York University; Stanford University; United States Department of Energy (DOE); SLAC National Accelerator Laboratory; Stanford University; Stanford University; Stanford University; New York University
摘要：Lymphocyte activation gene - 3 (LAG - 3) is an inhibitory receptor expressed on activated T cells and an emerging immunotherapy target. Domain 1 (D1) of LAG - 3, which has been purported to directly interact with major histocompatibility complex class II (MHCII) and fibrinogen-like protein 1 (FGL1), has been the major focus for the development of therapeutic antibodies that inhibit LAG - 3 receptor- ligand interactions and restore T cell function. Here, we present a high- resolution structure ...
