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作者：Zhong, Jia-Xin; Ji, Jun; Xia, Xiaoxing; Heo, Hyeonu; Jing, Yun
作者单位：Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; United States Department of Energy (DOE); Lawrence Livermore National Laboratory
摘要：Delivering audible content to a targeted listener without disturbing others is paramount in audio engineering. However, achieving this goal has long been challenging due to the diffraction of low-frequency (long-wavelength) audio waves in linear acoustics. Here, we introduce an approach for creating remote audio spots, dubbed audible enclaves, by harnessing the local nonlinear interaction of two self-bending ultrasonic beams with distinct spectra. The self-bending ultrasonic beams created by a...
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作者：Bermond, Baptiste; Wawrzynczak, Rafal; Zherlitsyn, Sergei; Kotte, Tommy; Helm, Toni; Gorbunov, Denis; Gu, Genda; Li, Qiang; Janasz, Filip; Meng, Tobias; Menges, Fabian; Felser, Claudia; Wosnitza, Joachim; Grushin, Adolfo; Carpentier, David; Gooth, Johannes; Galeski, Stanislaw
作者单位：Centre National de la Recherche Scientifique (CNRS); Ecole Normale Superieure de Lyon (ENS de LYON); Universite Paris Cite; Max Planck Society; Helmholtz Association; Helmholtz-Zentrum Dresden-Rossendorf (HZDR); Helmholtz Association; Helmholtz-Zentrum Dresden-Rossendorf (HZDR); United States Department of Energy (DOE); Brookhaven National Laboratory; State University of New York (SUNY) System; Stony Brook University; University of Luxembourg; Technische Universitat Dresden; Technische Universitat Dresden; Technische Universitat Dresden; Centre National de la Recherche Scientifique (CNRS); Communaute Universite Grenoble Alpes; Institut National Polytechnique de Grenoble; Universite Grenoble Alpes (UGA); University of Bonn
摘要：Oscillations of conductance observed in strong magnetic fields are a striking manifestation of the quantum dynamics of charge carriers in solids. The large charge carrier density in typical metals sets the scale of oscillations in both electrical and thermal conductivity, which characterize the Fermi surface. In semimetals, thermal transport at low-charge carrier density is expected to be phonon dominated, yet several experiments observe giant quantum oscillations in thermal transport. This ra...
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作者：Di Caro, Valeria; Cesari, Paola; Sala, Francesco; Cattaneo, Luigi; Strick, Peter
作者单位：University of Verona; University of Verona; University of Trento; University of Trento
摘要：Visually guided grasping is a fundamental building block of animal behavior, the specific neural mechanisms of which remain poorly documented in the human brain. We have mapped the causal contribution of different brain parts to grasping behavior by studying the kinematic parameters of 33 patients with brain tumors, engaged in actions directed toward objects of different sizes. Using motion capture techniques, we analyzed the dynamics of grip aperture and wrist transport. Voxel-based lesion-sy...
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作者：Johnson, Evan C.
作者单位：University of Alberta
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作者：Manik, Mohammad K.; Pan, Mengqi; Xiao, Le; Gu, Weixi; Kim, Hyoyoung; Pospich, Sabrina; Hedger, Andrew; Vajjhala, Parimala R.; Lee, Morris Y. L.; Qian, Xiaoqi; Landsberg, Michael J.; Ve, Thomas; Nanson, Jeffrey D.; Raunser, Stefan; Stacey, Katryn J.; Wu, Hao; Kobe, Bostjan
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作者：Gong, Zhou; Zhang, Xu; Liu, Maili; Jin, Changwen; Hu, Yunfei
作者单位：Chinese Academy of Sciences; Innovation Academy for Precision Measurement Science & Technology, CAS; Peking University; Chinese Academy of Sciences; Peking University
摘要：Despite the growing number of G protein-coupled receptor (GPCR) structures being resolved, the dynamic process of how GPCRs transit from the inactive toward the active state remains unclear. In this study, comprehensive molecular dynamics simulations were performed to explore how ligand binding modulates the conformational dynamics of the M2 muscarinic acetylcholine receptor (M2R). We observed a sequential occurrence of structural changes in the inactive- to- active transition of M2R induced b...
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作者：Wu, Yuanpeng; Xiao, Yixin; Zhao, Ying; Shen, Yifan; Sun, Kai; Wang, Boyu; Wang, Ping; Wang, Ding; Zhou, Peng; Wang, Danhao; Liu, Jiangnan; Hu, Mingtao; Norris, Theodore B.; Song, Jun; Mi, Zetian
作者单位：University of Michigan System; University of Michigan; McGill University; University of Michigan System; University of Michigan
摘要：Semiconductor quantum dots (QD) promise unique electronic, optical, and chemical properties, which can be exquisitely tuned by controlling the composition, size, and morphology. Semiconductor QDs have been synthesized primarily via two approaches, namely, epitaxial growth and wet- chemical synthesis. However, the properties of epitaxial QDs (eQDs) are susceptible to wetting layer formation and substrate dislocations, while colloidal QDs (cQDs) face fluorescence intermittency issues. Here, we r...
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作者：Sahoo, Pabitra K.; Agrawal, Manasi; Hanovice, Nicholas; Ward, Patricia J.; Desai, Meghal; Smith, Terika P.; Sima, HaoMin; Dulin, Jennifer N.; Vaughn, Lauren S.; Tuszynski, Mark H.; Welshhans, Kristy; Benowitz, Larry I.; English, Arthur W.; Houle, John D.; Twiss, Jeffery L.
作者单位：University of South Carolina System; University of South Carolina Columbia; Rutgers University System; Rutgers University Newark; University System of Ohio; Kent State University; Kent State University Salem; Kent State University Kent; Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Emory University; University of California System; University of California San Diego; Texas A&M University System; Texas A&M University College Station; University of South Carolina System; University of South Carolina Columbia; Drexel University
摘要：Depletion or inhibition of core stress granule proteins, G3BP1 in mammals and TIAR-2 in Caenorhabditis elegans, increases the growth of spontaneously regenerating axons. Inhibition of G3BP1 by expression of its acidic or B-domain accelerates axon regeneration after nerve injury, bringing a potential therapeutic strategy for peripheral nerve repair. Here, we asked whether G3BP1 inhibition is a viable strategy to promote regeneration in injured mammalian central nervous system (CNS) where axons ...
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作者：Battersby, Stephen
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作者：Yang, Darian T.; Chong, Lillian T.; Gronenborn, Angela M.
作者单位：Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Carnegie Mellon University; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh
摘要：The HIV-1 capsid protein (CA) assembles into a conical shell during viral maturation, encasing and protecting the viral RNA genome. The C-terminal domain (CTD) the two-domain capsid protein dimerizes, and this dimer connects individual chains in the mature capsid lattice. Previous NMR studies have shown that different dimer arrangements can be formed by isolated capsid protein chains and in assembled capsid lattices; however, the dynamics and functional relevance of these alternate dimers are ...
