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作者:Forster, Mirko; Ukoji, Nnanna; Sahle, Christoph J.; Niskanen, Johannes; Sakrowski, Robin; Surmeier, Goran; Weis, Christopher; Irifune, Tetsuo; Imoto, Sho; Yavas, Hasan; Huotari, Simo; Marx, Dominik; Sternemann, Christian; Tse, John S.
作者单位:Dortmund University of Technology; University of Saskatchewan; European Synchrotron Radiation Facility (ESRF); University of Turku; Ehime University; Ruhr University Bochum; Helmholtz Association; Deutsches Elektronen-Synchrotron (DESY); Stanford University; United States Department of Energy (DOE); SLAC National Accelerator Laboratory; University of Helsinki
摘要:Despite its ubiquitous nature, the atomic structure of water in its liquid state is still controversially debated. We use a combination of X-ray Raman scattering spectroscopy in conjunction with ab initio and path integral molecular dynamics simulations to study the local atomic and electronic structure of water under high pressure conditions. Systematically increasing fingerprints of non-hydrogen-bonded H2O molecules in the first hydration shell are identified in the experimental and computat...
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作者:Sakai, Hiroshi; Uno, Hideaki; Yamakawa, Harumi; Tanaka, Kaori; Ikedo, Aoi; Uezumi, Akiyoshi; Ohkawa, Yasuyuki; Imai, Yuuki
作者单位:Ehime University; Ehime University; Kyushu University; Kyushu University
摘要:Androgens exert their effects primarily by binding to the androgen receptor (AR), ligand- dependent nuclear receptor. While androgens have anabolic effects on skeletal muscle, previous studies reported that AR functions in myofibers to regulate skeletal muscle quality, rather than skeletal muscle mass. Therefore, the anabolic effects of androgens are exerted via nonmyofiber cells. In this context, the cellular and molecular mechanisms of AR in mesenchymal progenitors, which play a crucial role...
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作者:Woerman, Amanda L.; Kazmi, Sabeen A.; Patel, Smita; Aoyagi, Atsushi; Oehler, Abby; Widjaja, Kartika; Mordes, Daniel A.; Olson, Steven H.; Prusiner, Stanley B.
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作者:Lee, Yu-Chi; Liu, Wei; Fedorov, Alexey, V; Feldl, Nicole; Taylor, Patrick C.
作者单位:University of California System; University of California Riverside; Yale University; University of California System; University of California Santa Cruz; National Aeronautics & Space Administration (NASA); NASA Langley Research Center
摘要:Enhanced warming of the Arctic region relative to the rest of the globe, known Arctic amplification, is caused by a variety of diverse factors, many of which are influenced by the Atlantic meridional overturning circulation (AMOC). Here, we quantify the role of AMOC changes in Arctic amplification throughout the twenty- first century by comparing two suites of climate model simulations under the same climate change scenario but with two different AMOC states: one with a weakened AMOC and anoth...
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作者:Wu, Shaoyuan; Rheindt, Frank E.; Zhang, Jin; Wang, Jiajia; Zhang, Lei; Quan, Cheng; Li, Zhiheng; Wang, Min; Wu, Feixiang; Qu, Yanhua; Edwards, Scott, V; Zhou, Zhonghe; Liu, Liang
作者单位:Jiangsu Normal University; National University of Singapore; Changsha University of Science & Technology; Chang'an University; Chinese Academy of Sciences; Institute of Vertebrate Paleontology & Paleoanthropology, CAS; Chinese Academy of Sciences; Institute of Zoology, CAS; Harvard University; University System of Georgia; University of Georgia
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作者:Cho, Stella E.; Li, Wei; Beard, Andrew M.; Jackson, Jonathan A.; Kiernan, Risa; Hoshino, Kazunori; Martin, Adam C.; Sun, Jianjun
作者单位:University of Connecticut; Massachusetts Institute of Technology (MIT); Harvard University; University of Connecticut; University of Connecticut
摘要:Ovulation is critical for sexual reproduction and consists of the process of liberating fertilizable oocytes from their somatic follicle capsules, also known as follicle rupture. The mechanical force for oocyte expulsion is largely unknown in many species. Our previous work demonstrated that Drosophila ovulation, as in mammals, requires the proteolytic degradation of the posterior follicle wall and follicle rupture to release the mature oocyte from a layer of somatic follicle cells. Here, we i...
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作者:Epper, Thomas F.; Fehr, Ernst; Kreiner, Claus Thustrup; Leth-Petersen, Soren; Olufsen, Isabel Skak; Skov, Peer Ebbesen
作者单位:Universite de Lille; IESEG School of Management; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute for Humanities & Social Sciences (INSHS); University of Copenhagen; University of Zurich; Auckland University of Technology
摘要:Rising inequality has brought redistribution back on the political agenda. In theory, inequality aversion drives people's support for redistribution. People can dislike both advantageous inequality (comparison relative to those worse off) and disadvantageous inequality (comparison relative to those better off). Existing experimental evidence reveals substantial variation across people in these preferences. However, evidence is scarce on the broader role of these two distinct forms of inequalit...
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作者:Goldstein, Joseph L.
作者单位:University of Texas System; University of Texas Southwestern Medical Center
摘要:The Dutch painter Piet Mondrian, famous for his geometric grid paintings, was an ardent jazz fan. In the late stage of his career, he became intrigued with boogie- woogie music, which inspired him to paint his masterpiece Broadway Boogie Woogie. While boogie- woogie and science operate in different domains, both share the characteristics of experimentation, improvisation, and pushing boundaries-whether it is creating new piano rhythms and melodies or creating new ways to discover innovative so...
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作者:Yan, Zhiyuan; Handoko, Albertus Denny; Wu, Weikang; Yang, Chuchu; Wang, Hao; Yilmaz, Meltem; Zhang, Zhiyong; Cheng, Libo; Cheng, Xinbin; Ho, Ghim Wei; Feng, Bin; Shibata, Naoya; Zhao, Rong; Yang, Joel K. W.; Chong, Chong Tow; Ikuhara, Yuichi; Qiu, Cheng - Wei
作者单位:National University of Singapore; Agency for Science Technology & Research (A*STAR); A*STAR - Institute of Materials Research & Engineering (IMRE); Shandong University; University of Tokyo; Singapore University of Technology & Design; University of London; University College London; Tongji University; Tsinghua University; National University of Singapore
摘要:Metamaterial has been captivated a popular notion, offering photonic functionalities beyond the capabilities of natural materials. Its desirable functionality primarily relies on well- controlled conditions such as structural resonance, dispersion, geometry, filling fraction, external actuation, etc. However, its fundamental building blocks-meta- atoms-still rely on naturally occurring substances. Here, we propose and validate the concept of gradient and reversible atomic- engineered metamater...
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作者:Hur, Jihyun K.; Heffner, Joseph; Feng, Gloria W.; Joormann, Jutta; Rutledge, Robb B.
作者单位:Yale University; Yale University; Yale University; University of London; University College London
摘要:The prevalence of depression is a major societal health concern, and there is an ongoing need to develop tools that predict who will become depressed. Past research suggests that depression changes the language we use, but it is unclear whether language is predictive of worsening symptoms. Here, we test whether the sentiment of brief written linguistic responses predicts changes in depression. Across two studies (N = 467), participants provided responses to neutral open-ended questions, narrat...