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作者：Liao, Zhiyi; Wang, Chaoming; Tang, Xiaopeng; Yang, Mengli; Duan, Zilei; Liu, Lei; Lu, Shuaiyao; Ma, Lei; Cheng, Ruomei; Wang, Gan; Liu, Hongqi; Yang, Shuo; Xu, Jingwen; Tadese, Dawit Adisu; Mwangi, James; Kamau, Peter Muiruri; Zhang, Zhiye; Yang, Lian; Liao, Guoyang; Zhao, Xudong; Peng, Xiaozhong; Lai, Ren
作者单位：Chinese Academy of Sciences; Chinese Academy of Sciences; Kunming Institute of Zoology, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Qingdao University; Chinese Academy of Medical Sciences - Peking Union Medical College; Institute of Medical Biology - CAMS; Sichuan University; Chinese Academy of Sciences; Kunming Institute of Botany, CAS
摘要：Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been detected in almost all organs of coronavirus disease-19 patients, although some organs do not express angiotensin-converting enzyme-2 (ACE2), a known receptor of SARS-CoV-2, implying the presence of alternative receptors and/or co-receptors. Here, we show that the ubiquitously distributed human transferrin receptor (TfR), which binds to diferric transferrin to traffic between membrane and endosome for the iron deli...
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作者：Trost, Wiebke; Trevor, Caitlyn; Fernandez, Natalia; Steiner, Florence; Fruhholz, Sascha
作者单位：University of Zurich; University of Zurich; Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Oslo
摘要：Music is powerful in conveying emotions and triggering affective brain mechanisms. Affective brain responses in previous studies were however rather inconsistent, potentially because of the non- adaptive nature of recorded music used so far. Live music instead can be dynamic and adaptive and is often modulated in response to audience feedback to maximize emotional responses in listeners. Here, we introduce a setup for studying emotional responses to live music in a closed- loop neurofeedback s...
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作者：Kojima, Yosuke; Ito, Ryosuke K.; Fukuyama, Ibuki; Ohkubo, Yusaku; Durso, Andrew M.
作者单位：Toho University; Kyoto University; Kyoto University; Okayama University; State University System of Florida; Florida Gulf Coast University
摘要：Warning coloration and Batesian mimicry are classic examples of Darwinian evolution, but empirical evolutionary patterns are often paradoxical. We test whether foraging costs predict the evolution of striking coloration by integrating genetic and ecological data for aposematic and mimetic snakes (Elapidae and Dipsadidae). Our phylogenetic comparison on a total of 432 species demonstrated that dramatic changes in coloration were well predicted by foraging strategy. Multiple tests consistently i...
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作者：Du, Chenyu; Sheng, Jianping; Zhong, Fengyi; He, Ye; Liu, Huiyu; Sun, Yanjuan; Dong, Fan
作者单位：University of Electronic Science & Technology of China; University of Electronic Science & Technology of China
摘要：Photo- catalytic CO2 reduction with perovskite quantum dots (QDs) shows potential for solar energy storage, but it encounters challenges due to the intricate multi- electron photoreduction processes and thermodynamic and kinetic obstacles associated with them. This study aimed to improve photo- catalytic performance by addressing surface barriers and utilizing multiple- exciton generation in perovskite QDs. A facile surface engineering method was employed, involving the grafting of ferrocene c...
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作者：Kamii, Yasuhiro; Hayashizaki, Koji; Kanno, Toshio; Chiba, Akio; Ikegami, Taku; Saito, Mitsuru; Akeda, Yukihiro; Ohteki, Toshiaki; Kubo, Masato; Yoshida, Kiyotsugu; Kawakami, Kazuyoshi; Oishi, Kazunori; Araya, Jun; Kuwano, Kazuyoshi; Kronenberg, Mitchell; Endo, Yusuke; Kinjo, Yuki
作者单位：Jikei University; Jikei University; Jikei University; Kazusa DNA Research Institute; Jikei University; Japan Institute for Health Security (JIHS); National Institute of Infectious Diseases (NIID); Institute of Science Tokyo; Tokyo Medical & Dental University (TMDU); Tokyo University of Science; Jikei University; Tohoku University; La Jolla Institute for Immunology; University of California System; University of California San Diego
摘要：Invariant natural killer T (iNKT) cells are innate-like T lymphocytes that express an invariant T cell receptor alpha chain and contribute to bridging innate and acquired immunity with rapid production of large amounts of cytokines after stimulation. Among effecter subsets of iNKT cells, follicular helper NKT (NKTFH) cells are specialized to help B cells. However, the mechanisms of NKTFH cell differentiation remain to be elucidated. In this report, we studied the mechanism of NKTFH cell differ...
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作者：Krammer, Florian; Palese, Peter
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作者：Pan, Xinyue; Hsiao, Vincent; Nau, Dana S.; Gelfand, Michele J.
作者单位：The Chinese University of Hong Kong, Shenzhen; The Chinese University of Hong Kong, Shenzhen; University System of Maryland; University of Maryland College Park; University System of Maryland; University of Maryland College Park; Stanford University; Stanford University
摘要：Gossip, the exchange of personal information about absent third parties, is ubiquitous in human societies. However, the evolution of gossip remains a puzzle. The current article proposes an evolutionary cycle of gossip and uses an agent- based evolutionary game- theoretic model to assess it. We argue that the evolution of gossip is the joint conse-quence of its reputation dissemination and selfishness deterrence functions. Specifically, the dissemination of information about individuals' reput...
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作者：Das Gupta, Kaustav; Curson, James E. B.; Tarique, Abdullah A.; Kapetanovic, Ronan; Schembri, Mark A.; Fantino, Emmanuelle; Sly, Peter D.; Sweet, Matthew J.
作者单位：University of Queensland; University of Queensland; University of Queensland; Friedrich Miescher Institute for Biomedical Research; Universite de Tours; INRAE; University of Queensland
摘要：Cystic fibrosis transmembrane conductance regulator (CFTR) is an anion transporter required for epithelial homeostasis in the lung and other organs, with CFTR mutations leading to the autosomal recessive genetic disease CF. Apart from excessive mucus accumulation and dysregulated inflammation in the airways, people with CF (pwCF) exhibit defective innate immune responses and are susceptible to bacterial respiratory pathogens such as Pseudomonas aeruginosa. Here, we investigated the role of CFT...
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作者：Kulak, Klaudia; Kuska, Katarzyna; Colineau, Lucie; Mckay, Marina; Maziarz, Karolina; Slaby, Julia; Blom, Anna M.; King, Ben C.
作者单位：Lund University
摘要：One of the hallmarks of type 1 but also type 2 diabetes is pancreatic islet inflammation, associated with altered pancreatic islet function and structure, if unresolved. IL-1 beta is a proinflammatory cytokine which detrimentally affects beta-cell function. In the course of diabetes, complement components, including the central complement protein C3, are deregulated. Previously, we reported high C3 expression in human pancreatic islets, with upregulation after IL-1 beta treatment. In the curre...
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作者：Liao, Xuelong; Chen, Shan; Chen, Jialei; Li, Youzeng; Wang, Wei; Lu, Tiantian; Chen, Zhuo; Cao, Lixin; Wang, Yaxin; Huang, Rong; Sun, Xiaoting; Lv, Runyu; Wang, Huan
作者单位：Nankai University
摘要：Tremendous attention has been paid to the water-associated side reactions and zinc (Zn) dendrite growth on the electrode-electrolyte interface. However, the Zn pulverization that can cause continuous depletion of active Zn metal and exacerbate hydrogen evolution is severely neglected. Here, we disclose that the excessive Zn feeding that causes incomplete crystallization is responsible for Zn pulverization formation through analyzing the thermodynamic and kinetics process of Zn deposition. On t...
