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作者：Wei, Lingnan; Xu, Qiaoling; He, Yangchen; Li, Qingxin; Huang, Yan; Zhu, Wang; Watanabe, Kenji; Taniguchi, Takashi; Claassen, Martin; Rhodes, Daniel A.; Kennesh, Dante M.; Xian, Lede; Rubio, Angel; Wang, Lei
作者单位：Nanjing University; Songshan Lake Materials Laboratory; Sichuan Normal University; University of Wisconsin System; University of Wisconsin Madison; National Institute for Materials Science; National Institute for Materials Science; University of Pennsylvania; RWTH Aachen University; Max Planck Society; Simons Foundation; Flatiron Institute; Collaborative Innovation Center of Advanced Microstructures (CICAM); Nanjing University
摘要：Different mechanisms driving a linear temperature dependence of the resistivity rho - T at van Hove singularities (VHSs) or metal- insulator transitions when doping a Mott insulator are being debated intensively with competing theoretical proposals. We experimentally investigate this using the exceptional tunability of twisted bilayer (TB) WSe2 by tracking the parameter regions where linear-in- Tresistivity is found in dependency of displacement fields, filling, and magnetic fields. We find th...
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作者：Lathe, Rahul S.; McFarlane, Heather E.; Kesten, Christopher; Wang, Liu; Khan, Ghazanfar Abbas; Ebert, Berit; Ramirez-Rodriguez, Eduardo Antonio; Zheng, Shuai; Noord, Niels; Frandsen, Kristian; Bhalerao, Rishikesh P.; Persson, Staffan
作者单位：University of Copenhagen; Max Planck Society; Swedish University of Agricultural Sciences; Umea University; University of Toronto; University of Melbourne; La Trobe University; Ruhr University Bochum; Shanghai Jiao Tong University
摘要：Adjacent plant cells are connected by specialized cell wall regions, called middle lamellae, which influence critical agricultural characteristics, including fruit ripening and organ abscission. Middle lamellae are enriched in pectin polysaccharides, specifically homogalacturonan (HG). Here, we identify a plant- specific Arabidopsis DUF1068 protein, called NKS1/ELMO4, that is required for middle lamellae integrity and cell adhesion. NKS1 localizes to the Golgi apparatus and loss of NKS1 result...
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作者：Su, Zhengping; Duan, Yu; Tian, Yusong; Guo, Shukuan; Li, Penghui; Wang, Lin; Bu, Yeqiang; Nie, Anmin; Wang, Hongtao; Tian, Yongjun; Yang, Wei
作者单位：Zhejiang University; Suzhou Laboratory; Zhejiang University; Yanshan University
摘要：The structure of dislocation cores, the fundamental knowledge on crystal plasticity, remains largely unexplored in covalent crystals. Here, we conducted atomically resolved characterizations of dislocation core structures in a plastically deformed diamond anvil cell tip that was unloaded from an exceptionally high pressure of 360 GPa. Our observations unveiled a series of nonequilibrium dislocation cores that deviate from the commonly accepted five- seven- membered ring dislocation core model ...
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作者：Chen, Ruofan; Glauninger, Hendrik; Kahan, Darren N.; Shangguan, Julia; Sachleben, Joseph R.; Riback, Joshua A.; Drummond, D. Allan; Sosnick, Tobin R.
作者单位：Baylor College of Medicine; University of Chicago; University of Chicago; University of Chicago; University of Chicago; University of Chicago
摘要：Eukaryotic cells form condensates to sense and adapt to their environment [S. F. Banani, H. O. Lee, A. A. Hyman, M. K. Rosen, Nat. Rev. Mol. Cell Biol. 18, 285-298 (2017), H. Yoo, C. Triandafillou, D. A. Drummond, J. Biol. Chem. 294, 7151-7159 (2019)]. Poly(A)- binding protein (Pab1), a canonical stress granule marker, condenses upon heat shock or starvation, promoting adaptation [J. A. Riback et al., Cell 168, 1028-1040. e19 (2017)]. The molecular basis of condensation has remained elusive du...
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作者：Guo, Wei; Wenz, Leonie; Auffhammer, Maximilian
作者单位：Centro Euro-Mediterraneo sui Cambiamenti Climatici (CMCC); Potsdam Institut fur Klimafolgenforschung; University of California System; University of California Berkeley; National Bureau of Economic Research
摘要：Renewable power generation is the key to decarbonizing the electricity system. Wind power is the fastest -growing renewable source of electricity in the United States. However, expanding wind capacity often faces local opposition, partly due to a perceived visual disamenity from large wind turbines. Here, we provide a US -wide assessment of the externality costs of wind power generation through the visibility impact on property values. To this end, we create a database on wind turbine visibili...
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作者：Krushinski, Lynn E.; Dick, Jeffrey E.
作者单位：Purdue University System; Purdue University; Purdue University System; Purdue University
摘要：Recent reports have detailed the striking observation that electroactive molecules, such as hydrogen peroxide (H2O2) and radical water species (H2O center dot+/H2O center dot-), are spontaneously produced in aqueous microdroplets. Stochastic electrochemistry allows one to study reactions in real-time occurring inside subfemtoliter droplets, one droplet at a time, when a microdroplet irreversibly adsorbs to an ultramicroelectrode surface (radius similar to 5 mu m). Here, we use stochastic elect...
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作者：Obrien, Stephen J.
作者单位：Nova Southeastern University; Indiana University System; Indiana University Bloomington
摘要：The discovery of the 32-bp deletion allele of the chemokine receptor gene CCR5 showed that homozygous carriers display near-complete resistance to HIV infection, irrespective of exposure. Algorithms of molecular evolutionary theory suggested that the CCR5-Delta 32 mutation occurred but once in the last millennium and rose by strong selective pressure relatively recently to a similar to 10% allele frequency in Europeans. Several lines of evidence support the hypothesis that CCR5-Delta 32 was se...
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作者：Skrbek, Ladislav; Schmoranzer, David; Sreenivasan, Katepalli R.
作者单位：Charles University Prague; New York University; New York University Tandon School of Engineering
摘要：Transition from laminar to turbulent states of classical viscous fluids is complex and incompletely understood. Transition to quantum turbulence (QT), by which we mean the turbulent motion of quantum fluids such as helium II, whose physical properties depend on quantum physics in some crucial respects, is naturally more complex. This increased complexity arises from superfluidity, quantization of circulation, and, at finite temperatures below the critical, the two -fluid behavior. Transition t...
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作者：Lupia, Arthur; Allison, David B.; Jamieson, Kathleen Hall; Heimberg, Jennifer; Skipper, Magdalena; Wolf, Susan M.
作者单位：University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; Indiana University System; Indiana University Bloomington; University of Pennsylvania; National Academies of Sciences, Engineering & Medicine; University of Minnesota System; University of Minnesota Twin Cities
摘要：In recent years, many questions have been raised about whether public confidence in science is changing. To clarify recent trends in the public's confidence and factors that are associated with these feelings, an effort initiated by the National Academies' Strategic Council for Research Excellence, Integrity, and Trust (the Strategic Council) analyzed findings from multiple survey research organizations. The Strategic Council's effort, which began in 2022, found that U.S. public confidence in ...
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作者：Nakamura, Teruya; Ohyama, Chiaki; Sakamoto, Madoka; Toma, Tsugumasa; Tateishi, Hiroshi; Matsuo, Mihoko; Chirifu, Mami; Ikemizu, Shinji; Morioka, Hiroshi; Fujita, Mikako; Inoue, Jun- ichiro; Yamagata, Yuriko
作者单位：Kumamoto University; Kumamoto University; University of Tokyo
摘要：Nuclear factor KB (NF -KB) is activated by various inflammatory and infectious molecules and is involved in immune responses. It has been elucidated that ADP-(3-D- manno- heptose (ADP-Hep), a metabolite in gram- negative bacteria, activates NF -KB through alpha- kinase 1 (ALPK1)-TIFA-TRAF6 signaling. ADP-Hep stimulates the kinase activity of ALPK1 for TIFA phosphorylation. Complex formation between phosphorylation- dependent TIFA oligomer and TRAF6 promotes the polyubiquitination of TRAF6 for ...
