26期

最新文章

• SARS-CoV-2 nucleocapsid protein directly prevents cGAS-DNA recognition through competitive binding AI翻译
  作者：Gutmann, Theresia; Kuster, David; Hyman, Anthony A.
  作者单位：Max Planck Society
  摘要：A hallmark of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is the delayed interferon response. Interferons are typically produced upon host recognition of pathogen-or damage-associated molecular patterns, such as nucleic acids. While the mechanisms by which SARS-CoV-2 evades host recognition of its RNA are well studied, how it evades immune responses to cytosolic DNA-leaked from mitochondria or nuclei during infection-remains poorly understood. Here, we demonstrate th...
• Light controls gene functions through alternative splicing in fungi AI翻译
  作者：Li, Yifan; Lu, Huanhong; Guo, Degang; Li, Xiaoyan; Qi, Fei; Zhang, Jian; Fischer, Reinhard; Shen, Qirong; Yu, Zhenzhong
  作者单位：Nanjing Agricultural University; Xiamen University; Helmholtz Association; Karlsruhe Institute of Technology
  摘要：Light controls important biological processes in fungi by regulating transcriptional gene activation. Here, we found that beyond the regulation of mRNA transcript abundance, light regulates alternative splicing (AS) in the filamentous fungi Aspergillus nidulans, Trichoderma guizhouense, and Neurospora crassa. Blue light-regulated AS was involved in ergothioneine biosynthesis and conidiation in T.guizhouense, which required the blue light receptor BLR1. Blue light activated the MAPK HOG (Sak) p...
• Big evolutionary fireworks in tiny glass houses AI翻译
  作者：Banson, Idan; Brown, Matthew W.
  作者单位：Mississippi State University; Mississippi State University
• On the relationship between genes and environment AI翻译
  作者：Hirbo, Jibril B.; Were, Martin C.; Jones-Paris, Celestial R.
  作者单位：Vanderbilt University; Vanderbilt University; Vanderbilt University; Vanderbilt University
• Roughness- dependent scaling of the contact area and separation gap with pressure for glassy polymers AI翻译
  作者：Patil, Utkarsh; Kumar, Shubhendu; Merriman, Stephen; Dhinojwala, Ali
  作者单位：University System of Ohio; University of Akron
  摘要：The contact between two rough surfaces has been a topic of significant interest since early studies on Coulombic friction and remains crucial for numerous technological applications. However, theoretical progress has outpaced experiments due to the challenges in measuring contact areas across scales ranging from subnanometers to macroscopic dimensions. Here, we demonstrate the use of commonly available infrared-based (IR) spectroscopy in combination with finite-difference time-domain (FDTD) op...
• Photothermal catalysis of waste plastics into propionic acid and hydrogen via Ni single- atom site isolation effect AI翻译
  作者：Yue, Shuai; Liu, Yixiao; Zhao, Zhiyong; Zhao, Guanshu; Yang, Mengxue; Zhang, Tao; Li, Fei; Liu, Kewang; Wang, Pengfei; Zhan, Sihui; Jia, Jinhu
  作者单位：Nankai University; University of Toronto; Tianjin University
  摘要：Currently, catalytic recycling of polyethylene (PE) into high-value chemicals using solar energy often faces poor product selectivity and low efficiency. This is mainly due to the difficulty in effectively controlling the intermediates during PE photoreforming and the long-standing challenge of inefficient charge dynamics. Here, we present a solar-driven photothermal catalytic approach for the selective conversion of PE waste into propionic acid and hydrogen under ambient conditions. Atomicall...