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作者：Niwa, Taiki; Uno, Yoshinobu; Ohishi, Yuta; Kadota, Mitsutaka; Aburatani, Naotaka; Kiyatake, Itsuki; Katooka, Daiki; Yorozu, Michikazu; Tsuzuki, Nobutaka; Toyoda, Atsushi; Takagi, Wataru; Nakamura, Masaru; Kuraku, Shigehiro
作者单位：Graduate University for Advanced Studies - Japan; Research Organization of Information & Systems (ROIS); National Institute of Genetics (NIG) - Japan; RIKEN; Tokushima University; Kobe University; University of Tokyo; Research Organization of Information & Systems (ROIS); National Institute of Genetics (NIG) - Japan; RIKEN; University of Michigan System; University of Michigan
摘要：Sex determination has been investigated across vertebrate lineages to reveal the stepwise evolution of sex chromosomes and the diversity of responsible molecular mechanisms. However, these studies rarely include cartilaginous fishes, which diverged from the other vertebrates 450 Mya, hindering the comprehensive view of vertebrate sex determination. Here, we produced chromosome-scale genome assemblies of egg-laying shark species and comparatively investigated genome sequences and transcriptome ...
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作者：Viegas, Jennifer
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作者：An, Jiafu; Wang, Tenghui; Chen, Bin; Gong, Peng; Lin, Chen; Stenseth, Nils Chr.
作者单位：University of Hong Kong; Lingnan University; University of Hong Kong; University of Hong Kong; University of Hong Kong; Tsinghua University; University of Oslo; University of Oslo
摘要：Access to safely managed drinking water is a fundamental human right, essential for human health and well- being. However, 2.2 billion people around the world still lack this access, with significant geographical disparities. In this study, we leveraged the implementation of gender quota laws-specifically reserved parliamentary seats for women across African countries-to examine its impact on improved water availability. Our findings reveal that the implementation of gender quotas is associate...
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作者：Kanno, Shu; Sugisaki, Kenji; Nakamura, Hajime; Yamauchi, Hiroshi; Sakuma, Rei; Kobayashi, Takao; Gao, Qi; Yamamoto, Naoki
作者单位：Mitsubishi International Corporation (MIC); Mitsubishi Chemical Holdings Corporation; Mitsubishi Chemical; Keio University; Keio University; Keio University; SoftBank Corporation; JSR Corporation; Keio University
摘要：We develop an energy calculation algorithm leveraging quantum phase difference estimation (QPDE) scheme and a tensor-network-based unitary compression method in the preparation of superposition states and time-evolution gates. Alongside its efficient implementation, this algorithm reduces depolarization noise affections exponentially. We demonstrated energy gap calculations for one-dimensional Hubbard models on IBM superconducting devices using circuits up to 32-system (plus oneancilla) qubits...
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作者：Menon, Tejas; McQuilten, Hayley A.; Samir, Jerome; Nguyen, Thi H. O.; Lim, Ratana; Kaur, Jasveen; Rizzetto, Simone; Eltahla, Auda; Thomas, Paul G.; Lappas, Martha; Rossjohn, Jamie; Gras, Stephanie; Crowe, Jane; Flanagan, Katie L.; Luciani, Fabio; Doherty, Peter C.; van de Sandt, Carolien E.; Kedzierska, Katherine
作者单位：University of Melbourne; Peter Doherty Institute; University of New South Wales Sydney; University of Melbourne; University of Tasmania; University of Tasmania; St Jude Children's Research Hospital; Monash University; Monash University; Cardiff University; La Trobe University; Royal Melbourne Institute of Technology (RMIT); Clifford Craig Foundation; Launceston General Hospital
摘要：Central memory CD8+T cells (Tcm) represent the prominent memory T cell subset in human blood, yet the persistence of T cell receptor (TCR) clonotypic and transcriptional features of epitope-specific Tcm pools across the human lifespan remains unknown. We analyzed Tcm CD8+ T cells specific for HLA-A*02:01-M158-66 (A2/M158; a prominent influenza epitope) in newborns, children, adults, and older adults directly ex vivo. Our data provide evidence that epitope-specific Tcm CD8+ pools dominate influ...
