38期

最新文章

• Large-scale surveys of woodrats (Neotoma spp.) reveal constraints on diet breadth in herbivorous mammals AI翻译
  作者：Weinstein, Sara B.; Klure, Dylan M.; Symeonidi, Efthymia; Greenhalgh, Robert; Mayes, Marc T.; Doolin, Margaret L.; Stapleton, Tess E.; Swei, Andrea; Cove, Michael, V; Dearing, M. Denise
  作者单位：Utah System of Higher Education; Utah State University; Utah System of Higher Education; University of Utah; Utah System of Higher Education; Utah State University; California State University System; San Francisco State University
  摘要：Characterizing niche space is critical for predicting species interactions and responses to environmental change. To enhance our understanding of dietary niche breadth, we used DNA metabarcoding to examine how diets of a widespread, model herbivore (wood-rats, genus Neotoma) respond to changing resources and the extent to which dietary specialization is conserved across space and time. We used diet data from 13 species, 57 populations, and over 500 individuals to examine predictors of niche br...
• Reply to Possenriede et al.: LDLR as a targetable HlyA receptor in Escherichia coli pyelonephritis AI翻译
  作者：Kuhn, Hunter W.; Smither, Madeleine R.; Collins, Christina A.; Gaut, Joseph P.; Diamond, Michael S.; Hunstad, David A.
  作者单位：Washington University (WUSTL); Washington University (WUSTL); Washington University (WUSTL); Washington University (WUSTL)
• LDL receptor promotes urinary tract infection by α- hemolysin-producing Escherichia coli and long-term histopathologic sequelae in the kidney AI翻译
  作者：Possenriede, Lena; Sendtner, Georg W.; Falahat, Peyman; Miranda, Julia; Schmidt, Axel; Ludwig, Kerstin U.; von Vietinghoff, Sibylle
  作者单位：University of Bonn; University of Bonn
• Stress-induced preference for antioxidants by Drosophila AI翻译
  作者：Hwang, Gayoung; Yang, Dae-Wook; Geisseova, Terezia Klaudia; Kim, Hae A.; Oh, Yangkyun; Suh, Greg S. B.
  作者单位：Korea Advanced Institute of Science & Technology (KAIST); Ulsan National Institute of Science & Technology (UNIST); Korea Advanced Institute of Science & Technology (KAIST); Ewha Womans University
  摘要：In an ever- changing environment, animals make optimal decisions to ensure their nutrients they require to maintain homeostasis. Under extreme circumstances (e.g., infection), they may exhibit ingestive behaviors, such as seeking out substances (e.g., toxins) that suggest self- medication. Few studies, however, have investigated the mechanisms that ensue self- medication. Here, we report the selective intake of antioxidants by Drosophila melanogaster during a period of heat stress or sleep dep...
• Remembering ecologist Margaret Bryan Davis (1931-2024) AI翻译
  作者：Lynch, Elizabeth A.; Calcote, Randy; Zabinski, Catherine A.; Hotchkiss, Sara C.
  作者单位：University of Minnesota System; University of Minnesota Twin Cities; Montana State University System; Montana State University Bozeman; University of Wisconsin System; University of Wisconsin Madison
  摘要：Margaret Bryan Davis, a prominent ecologist, died on May 22, 2024. She was a Regents Professor at the University of Minnesota and a member of the National Academy of Sciences. Her students remember her as a creative and clear-thinking scientist who combined the tools and perspectives of paleoecology with ideas and problems of ecology in order to understand long-term forest dynamics. She was a champion of diversity and equity in science.
• Peritumoral macrophages recruit eosinophils to promote antitumor immune responses in breast cancer AI翻译
  作者：Saglimbeni, Joseph; Esteva, Eduardo; Canales, Josue; Perez, Oriana A.; Eichinger, Anna; Huntley, William; Khanna, Kamal M.; Dolgalev, Igor; Klar, Natalie; Adams, Sylvia; Reizis, Boris
  作者单位：New York University; New York University; New York University; University of Munich; New York University; New York University; NYU Langone Medical Center
  摘要：Breast tumors harbor dynamic microenvironments, with multiple immune cell types playing opposing roles during tumor progression and/or response to therapy. Tumor- associated macrophages promote mammary tumorigenesis, whereas the role of mammary tissue macrophages (MTMs) remains incompletely understood. High- dimensional immunostaining of murine mammary tumor progression revealed that MTMs were localized in the peritumoral stroma and associated with eosinophils, which were previously shown to f...
• A widespread family of ribosomal peptide metallophores involved in bacterial adaptation to metal stress (vol 121, e2408304121, 2024) AI翻译
  作者：Leprevost, Laura; Junge, Sophie; Lippens, Guy; Guillaume, Celine; Sicoli, Giuseppe; Oliveira, Lydie; Falcone, Enrico; de Santis, Emiliano; Rivera-Millot, Alex; Billon, Gabriel; Stellato, Francesco; Henry, Celine; Antoine, Rudy; Zirah, Severine; Dubiley, Svetlana; Li, Yanyan; Jacob-Dubuisson, Francoise
• Optimal transitions between nonequilibrium steady states AI翻译
  作者：Monter, Samuel; Loos, Sarah A. M.; Bechinger, Clemens
  作者单位：University of Konstanz; University of Cambridge; Max Planck Society
  摘要：The optimal control of finite-time processes on the microscale is of significant theoretical and practical interest, particularly for the energy-efficient operation of nanomachines. While previous studies have primarily focused on transitions between equilibrium states, many biologically and technologically relevant processes occur far from equilibrium. In such nonequilibrium settings, memory, a ubiquitous feature in realistic systems, plays an intricate role, as any driving necessarily excite...
• Spatiotemporal mapping of alloy mesostructure dynamics via multimodal coherent X-ray diffraction imaging AI翻译
  作者：Takazawa, Shuntaro; Ninomiya, Kakeru; Ha, Minh-Quyet; Vu, Tien-Sinh; Sasaki, Yuhei; Abe, Masaki; Uematsu, Hideshi; Okawa, Naru; Ishiguro, Nozomu; Ozaki, Kyosuke; Hatsui, Takaki; Hoshino, Taiki; Nishibori, Maiko; Dam, Hieu-Chi; Takahashi, Yukio
  作者单位：Tohoku University; Tohoku University; RIKEN; Tohoku University; Japan Advanced Institute of Science & Technology (JAIST); Tohoku University
  摘要：Understanding mesoscale structural dynamics of precipitation-strengthened alloys is essential for optimizing the mechanical performances of these alloys. Herein, we establish a multimodal coherent X-ray diffraction imaging framework for spatiotemporal mapping of mesoscale structural dynamics in precipitation-strengthened alloys. As a demonstrative application, we visualized the structural evolution in Mg97Zn1Gd2 during isothermal annealing at 700 K, revealing real-time dynamics of nucleation, ...
• Pseudouridine prevalence in Kaposi's sarcoma-associated herpesvirus transcriptome reveals an essential mechanism for viral replication AI翻译
  作者：Mottram, Timothy J.; Harper, Katherine L.; Vasconcelos, Elton J. R.; Whitehouse, Adrian
  作者单位：University of Leeds; University of Leeds; University of Leeds; Rhodes University
  摘要：Pseudouridylation is a prevalent RNA modification occurring in transfer RNAs (tRNAs), ribosomal RNAs (rRNAs), small non-coding RNAs (snoRNAs), and has been most recently identified in mRNAs and lncRNAs. Emerging evidence suggests that this dynamic RNA modification is implicated in altering gene expression by regulating RNA stability, modulating translation elongation, and modifying amino acid substitution rates. However, the role of pseudouridylation in infection is poorly understood. Herein, ...