4期

最新文章

• Soft giant magnetoimpedance electronics enable contact-free human-machine interactions AI翻译
  作者：Wu, Yizhang; Xing, Sicheng; Yang, Dingyi; Liu, Yihan; Ding, Chi; Li, Zifeng; Jiao, Qizhang; Zhang, Anran; Guo, Ziheng; Liu, Siyuan; Luo, Wei; Yuan, Gongkai; Wang, Meixiang; Wang, Yong; Dickey, Michael D.; Bai, Wubin
  作者单位：University of North Carolina; University of North Carolina Chapel Hill; Xidian University; Nanjing University; Johns Hopkins University; University of Tokyo; North Carolina State University
  摘要：Magnetic sensing enables contact-free, three-dimensional human-machine interactions (HMI) with high selectivity and resilience to environmental noise. However, conventional magnetic films, mostly obtained via vacuum deposition, remain constrained by rigidity, instantaneous response, and single-mode. Here, we report a giant magneto-impedance ionogel (GelGMI) in which electrostatically self-assembled ferromagnetic (FM) domains are uniformly dispersed in a soft ionogel matrix. Under a magnetic fi...
• Scaling the glassy dynamics of active particles: Tunable fragility and reentrance AI翻译
  作者：Pareek, Puneet; Sollich, Peter; Nandi, Saroj Kumar; Berthier, Ludovic
  作者单位：Tata Institute of Fundamental Research (TIFR); University of Gottingen; Centre National de la Recherche Scientifique (CNRS); Universite PSL; CNRS - Institute of Chemistry (INC); Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI)
  摘要：Understanding the influence of activity on dense amorphous assemblies is crucial for biological processes such as wound healing, embryogenesis, or cancer progression. Here, we study the effect of self-propulsion forces of amplitude f0 and persistence time tau p in dense assemblies of soft repulsive particles by simulating a model particle system that interpolates between particulate active matter and biological tissues. We identify the fluid and glass phases of the three-dimensional phase diag...
• The role of fibration symmetries in geometric deep learning AI翻译
  作者：Velarde, Osvaldo M.; Parra, Lucas C.; Boldi, Paolo; Makse, Hernan A.
  作者单位：City University of New York (CUNY) System; City College of New York (CUNY); University of Milan; City University of New York (CUNY) System; City College of New York (CUNY)
  摘要：Geometric Deep Learning (GDL) unifies a broad class of machine learning techniques from the perspectives of symmetries, offering a framework for introducing problem specific inductive biases like Graph Neural Networks (GNNs). However, the current formulation of GDL is limited to global symmetries. We propose to relax GDL to allow for local symmetries, specifically fibration symmetries, which only require isomorphic input trees-a property that is much more common in real-world graphs. We show t...
• Human action shapes the beaks of backyard birds AI翻译
  作者：Marzluff, John M.
  作者单位：University of Washington; University of Washington Seattle
• Liganded LolCDE structures reveal a common substrate- LolE interaction guiding bacterial lipoprotein transport AI翻译
  作者：Szewczyk, Paul; Greene, Nicholas P.; Symmons, Martyn F.; Hardwick, Steven W.; Koronakis, Vassilis
  作者单位：University of Cambridge; University of Cambridge
  摘要：Bacterial lipoproteins are key structural components of the outer membrane in Gram- negative bacteria and vital components of machineries required for its biosynthesis and maintenance. The Lol system, essential for viability, directs transport of lipoproteins from the site of biosynthesis on the inner membrane to the outer membrane and has been the target of extensive efforts to develop novel antimicrobial drugs. In the first stage of this transport process, newly synthesized lipoproteins are ...
• Social movements are transformative agents for biodiversity conservation AI翻译
  作者：Walter, Mariana; Scheidel, Arnim; Vadez, Clara; Del Bene, Daniela; Temper, Leah; Fanari, Eleonora; Reyes-Garcia, Victoria
  作者单位：Autonomous University of Barcelona; University of Cambridge; Universita Ca Foscari Venezia; ICREA; Autonomous University of Barcelona
  摘要：Civil society has long been a catalyst for social change by reshaping structures, influencing values, and challenging power dynamics; however, its role in driving transformative change for biodiversity remains underexplored. To address this gap, we analyze 2,801 socio-environmental mobilizations documented in the Environmental Justice Atlas (EJAtlas). These mobilizations produce diverse outcomes that reveal distinct spatial, temporal, and sectoral patterns and proactively and reactively respon...
• Structural basis for iterative methylation by a cobalamin-dependent radical S-adenosylmethionine enzyme in cystobactamids biosynthesis AI翻译
  作者：Cui, Jiayuan; Wang, Bo; Maurya, Ravi K.; Booker, Squire J.
  作者单位：Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; University of Pennsylvania; Howard Hughes Medical Institute; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; University of Pennsylvania; Pennsylvania Medicine
  摘要：Cystobactamids are nonribosomal peptide natural products that function as DNA gyrase inhibitors, exhibiting significant antibacterial activity. They are isolated from Cystobacter sp. Cbv34 and contain various alkoxy groups on para-aminobenzoic acid moieties, which are believed to play a crucial role in antibacterial functions. The alkoxy groups are generated by iterative methylations on a methoxy group by the cobalamin to three methylations to give ethoxy, isopropoxy, sec-butoxy, and tert-buto...
• STING single amino acid polymorphisms modulate iridovirus immune evasion and pathogenicity spectrum AI翻译
  作者：Qin, Xiaowei; Liang, Mincong; Pan, Weiqiang; Zhan, Zhipeng; Li, Chuanrui; You, Yanlin; Weng, Shaoping; He, Jianguo; Guo, Changjun
  作者单位：Sun Yat Sen University; Southern Marine Science & Engineering Guangdong Laboratory; Southern Marine Science & Engineering Guangdong Laboratory (Zhuhai); Sun Yat Sen University
  摘要：The evolutionary arms race between viruses and hosts shapes host antiviral defenses and viral immune evasion, yet the mechanisms driving divergence in viral cross-species pathogenicity remain unclear. Here, we investigated the role of single amino acid polymorphisms (SAPs) in stimulator of interferon genes (STING) in modulating immune evasion ubiquitination at residues C196 and K315, promoting its degradation to suppress interferon responses. Importantly, the K315/R315 polymorphism acts as a m...
• Force-dependent structural dynamics of the giant nesprin-2 AI翻译
  作者：Shang, Fei; Zhang, Yuhang; Ye, Jiaqing; Zhang, Zhuwei; Qi, Xingyu; Chen, Hu; Yu, Miao; Le, Shimin
  作者单位：Zhejiang University; Zhejiang University; Xiamen University
  摘要：The nesprin protein family serves as a critical physical bridge between the cytoskeleton-a fundamental structural scaffold and mechanotransduction hub of the cell, and the nucleus-an intriguing and emerging mechanoresponsive element. Due to the external mechanical cues and the nucleo-cytoskeletal dynamics, the nesprins are physiologically under forces. However, the dynamics of nesprins within physiological forces and loading rates remain largely unexplored. In this study, we employ magnetic-tw...
• A shear-induced limit on bacterial surface adhesion in fluid flow AI翻译
  作者：Yeo, Edwina F.; Walker, Benjamin J.; Pearce, Philip; Dalwadi, Mohit P.
  作者单位：University of London; University College London; University of London; University College London; University of Oxford
  摘要：Controlling bacterial surface adhesion and subsequent biofilm formation in fluid systems is crucial for the safety and efficacy of medical and industrial processes. Here, we theoretically examine the transport of bacteria close to surfaces, isolating how the key processes of bacterial motility and fluid flow interact and alter surface adhesion. We exploit the disparity between the fluid velocity and the swimming velocity of common motile bacteria and, using a hybrid asymptotic-computational ap...