4期

最新文章

• Disorder-induced stress-flow misalignment in soft glassy materials revealed using multidirectional shear AI翻译
  作者：Blanc, Frederic; Ovarlez, Guillaume; Trigui, Adam; Martens, Kirsten; Mari, Romain
  作者单位：Centre National de la Recherche Scientifique (CNRS); Universite Cote d'Azur; CNRS - Institute of Physics (INP); Centre National de la Recherche Scientifique (CNRS); Universite de Bordeaux; CNRS - Institute of Chemistry (INC); Communaute Universite Grenoble Alpes; Centre National de la Recherche Scientifique (CNRS); Universite Grenoble Alpes (UGA)
  摘要：Controlling the mechanical response of soft glassy materials-such as emulsions, foams, and colloidal suspensions-is key for many industrial processes. While their steady-state flow behavior is reasonably well understood, their response to complex flow histories, as encountered in operations like pumping or mixing, remains poorly known. Using a custom multiaxis shear apparatus that enables arbitrary changes flow direction, we investigate how shear history influences the mechanical behavior a mo...
• How much of the forest sink is passive? Case of the United States AI翻译
  作者：Davis, Eric C.; Sohngen, Brent; Lewis, David J.
  作者单位：United States Department of Agriculture (USDA); University System of Ohio; Ohio State University; Oregon State University
  摘要：Over time, carbon sequestered in temperate forests has increased, but the relative effects of passive and active drivers remain unclear. This study uses plot-level data to disentangle the contributions of six drivers (temperature, precipitation, CO2, management, age composition, and area) to these increases in 14 forest groups of the conterminous United States. From 2005 to 2022, the passive drivers (CO2, temperature, and precipicontributing most of the change. Among the anthropogenic drivers,...
• BORC assemblies integrate BLOC-1 subunits to diversify endosomal trafficking functions AI翻译
  作者：De Araujo, Mariana E. G.; Amann, Sascha J.; Stasyk, Taras; Schleiffer, Alexander; Rauch, Eva; Flumann, Paula; Singer, Isabel I.; Kremser, Leopold; Dostal, Vojtech; Laopanupong, Thanida; Obojes, Nikolaus; Wallnofer, Moritz H.; Gradl, Flora S.; Kurzbauer, Robert; Krebiehl, Caroline; Kofler, Samuel; Grishkovskaya, Irina; Vogel, Georg F.; Hess, Michael W.; Sarg, Bettina; Clausen, Tim; Haselbach, David; Huber, Lukas A.
  作者单位：Medical University of Innsbruck; Vienna Biocenter (VBC); Research Institute of Molecular Pathology (IMP); University of Vienna; Vienna Biocenter (VBC); Medical University of Vienna; Medical University of Vienna; Medical University of Innsbruck; European Academy of Bozen-Bolzano; Medical University of Innsbruck; Medical University of Innsbruck
  摘要：BORC and BLOC-1 are multisubunit complexes that regulate endolysosomal trafficking. Although they are presumed to be distinct, their paralogous origins and shared subunits suggest the potential for higher-order assembly. Here, we reveal the conserved octameric architecture of BORC formed by two intertwined tetramers and present the structure of C. elegans BORC. Through cross-linking mass spectrometry of endogenous complexes, we validate this model for human BORC and demonstrate that the integr...
• Reply to Dujmović: The alignment in cost between human and model reasoning is an empirical phenomenon worth explaining AI翻译
  作者：de Varda, Andrea Gregor; D'Elia, Ferdinando Pio; Kean, Hope; Lampinen, Andrew; Fedorenko, Evelina
  作者单位：Massachusetts Institute of Technology (MIT); University of Copenhagen; Alphabet Inc.; DeepMind
• Clever algorithms for glasses work by time reparameterization AI翻译
  作者：Ghimenti, Federico; Berthier, Ludovic; Kurchan, Jorge; van Wijland, Frederic
  作者单位：Universite Paris Cite; Universite Paris Cite; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute for Engineering & Systems Sciences (INSIS); Stanford University; Universite de Montpellier; Universite de Montpellier; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Physics (INP); Centre National de la Recherche Scientifique (CNRS); Universite PSL; CNRS - Institute of Chemistry (INC); Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI); Universite PSL; Universite Paris Cite; Ecole Normale Superieure (ENS)
  摘要：The ultraslow dynamics of glass-formers has been explained by two views often considered as mutually exclusive: One invokes locally hindered mobility, and the other rests on the complexity of the configuration space. Here, we show that time evolution responds strongly to details of the dynamics by changing the speed of time flow: It has time-reparameterization softness. This finding reconciles both views: While local constraints reparameterize the flow of time, the global landscape determines ...
• Evolutionary adaptations to the hormonal regulation of vascular tissue development AI翻译
  作者：Xiao, Wei; Verhelst, Eline; Yang, Ling; Ke, Yuji; De Rybel, Bert
  作者单位：Ghent University; Flanders Institute for Biotechnology (VIB); Chinese Academy of Sciences; South China Botanical Garden, CAS; Chinese Academy of Sciences; South China Botanical Garden, CAS
  摘要：Vascular tissues provide long-distance transport and physical support in the vascular plant lineage, providing a significant adaptive advantage. Although the cross talk between auxin and cytokinin in promoting both vascular cell proliferation and differentiation has been well studied in angiosperms such as Arabidopsis thaliana, little is known about this regulation in other vascular plant lineages. Here, we found that unlike the hormonal cross talk found in all other species under study, the l...
• Emergent ferromagnetism and unusual irreversible magnetoresistance in an intercalated van der Waals antiferromagnet AI翻译
  作者：Zhai, Zixin; Liu, Wenhao; Guo, Xiaoyu; Schulze, Daniel J.; Kuo, Ting -Wei; Agarwal, Nishkarsh; Stangel, Alex; Joshi, Pramanand; Liu, J. Ping; Deng, Liangzi; Hovden, Robert; Zhao, Liuyan; Chu, Ching -Wu; Lv, Bing
  作者单位：University of Texas System; University of Texas Dallas; University of Michigan System; University of Michigan; University of Houston System; University of Houston; University of Houston System; University of Houston; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; University of Texas System; University of Texas Arlington
  摘要：Orthorhombic air-stable two-dimensional (2D) antiferromagnet (AFM) CrSBr has attracted much research interest lately thanks to its rich magnetic behaviors together with its remarkable electronic, excitonic, and polaritonic properties. Here, we report a reliable electrochemical intercalation method by inserting large tetrabutylammonium (TBA+) ions into CrSBr layers. Magnetically, such intercalation efficiently suppresses the interlayer AFM and induces a ferromagnetic (FM) order with a much-enha...
• Cytoplasmic crowding acts as a porous medium reducing macromolecule diffusion AI翻译
  作者：Destrian, Olivier; Moisan, Nicolas; Mege, Rene-Marc; Ladoux, Benoit; Goyeau, Benoit; Chabanon, Morgan
  作者单位：Universite Paris Saclay; Centre National de la Recherche Scientifique (CNRS); Centre National de la Recherche Scientifique (CNRS); Universite Paris Cite; University of Erlangen Nuremberg; Max Planck Society
  摘要：Intracellular transport of macromolecules is crucial for the proper functioning of most cellular processes. Although intracellular crowding is known to strongly alter macromolecule mobility, how cytoplasmic structures physically modulate diffusion remains largely unexplored. Here, we investigated the mechanisms by which cytoplasmic crowding controls diffusivity using live-cell experiments and porous media modeling approaches. Confocal microscopy combined with fluorescence recovery after photob...
• Structural characterization of the HDV virion and its ribonucleoprotein AI翻译
  作者：Itskanov, Samuel; Ary, Beatrice; Mehra, Upasana; Lew, Irene; Novikov, Nikolai; Schmitz, Uli; Holdorf, Meghan M.; Beran, Rudolf K.; Lansdon, Eric B.
  作者单位：Gilead Sciences; Gilead Sciences; Gilead Sciences; Gilead Sciences
  摘要：Hepatitis D virus (HDV) is a small RNA satellite virus of hepatitis B virus (HBV) which encodes a single protein, HDV delta antigen (HDAg), that is required for replication. Viral replication occurs independently from HBV and relies primarily on host RNA polymerase(s). Bulevirtide, a viral entry inhibitor, is the only approved treatment for chronic HDV but has a low cure rate as a monotherapy, and most patients rebound following cessation of therapy. It is likely that an inhibitor targeting HD...
• A sexually dimorphic neuronal cluster in the mouse medial amygdala responds to male sexual status AI翻译
  作者：Licht, Tamar; Akarieh, Adan; Dhamshy, Aya; Zeisel, Amit; Ophir, Osnat; Rokni, Dan
  作者单位：Hebrew University of Jerusalem; Hebrew University of Jerusalem; Technion Israel Institute of Technology
  摘要：Increasing scientific interest has been directed toward understanding sexual dimorphism in the brain. Although several brain structures exhibit masculine or feminine characteristics, strictly binary anatomical feature, comparable to those observed in genitalia, has been rarely identified. In this study, we identified a dense, sexually dimorphic cluster of neurons in the posterodorsal medial amygdala (MeApd), which we named exhibited a remarkable binary pattern of c-fos promoter activation. Usi...