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作者：Yan, Jiaqi; Bhadane, Rajendra; Xu, Wentao; Ran, Meixin; Ma, Xiaochao; Li, Yuanqiang; Jahnke, Kevin; Ma, Xiaodong; Salo-Ahen, Outi M. H.; Kostiainen, Mauri A.; Weitz, David A.; Zhang, Hongbo
作者单位：Harvard University; Abo Akademi University; Wenzhou Medical University; University of Turku; University of Turku; Abo Akademi University; Max Planck Society; Abo Akademi University; Aalto University
摘要：Current methodologies for detecting the sequence of double-stranded DNA (dsDNA) require amplifying and denaturing the target into single-stranded DNA (ssDNA) to enable sequence detection through Watson-Crick base pairing. However, these approaches are limited by the risks of nonspecific amplification, reliance on complex, temperature-sensitive protein enzymes, and harsh reaction conditions, such as in strong base or acidic environments. Here, we introduce a dsDNA detection platform that integr...
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作者：O'Hara, Casey C.; Baez-Schon, Mabel; Chaplin-Kramer, Rebecca; Cheng, Samantha H.; Echeverri, Alejandra; Galford, Gillian L.; Gould, Rachelle K.; Mancilla, Cristina L.; Muldoon, Maura C.; Singh, Gerald G.; Baltezar, Priscilla; Kuwayama, Yusuke; Polasky, Stephen; Rodewald, Amanda D.; Sharp, Richard P.; Tennant, Elizabeth J.; Zhao, Jiaying; Halpern, Benjamin S.
作者单位：University of California System; University of California Santa Barbara; World Wildlife Fund; University of California System; University of California Berkeley; University of Vermont; University of Vermont; University of Victoria; Massachusetts Institute of Technology (MIT); University System of Maryland; University of Maryland Baltimore; University of Minnesota System; University of Minnesota Twin Cities; Cornell University; Cornell University; Cornell University; University of British Columbia; University of California System; University of California Santa Barbara
摘要：Remotely sensed Earth science information (ESI) has become increasingly central to addressing global challenges, yet its societal value, i.e., the difference ESI makes in real-world decisions and outcomes, is rarely quantified. In this study, we systematically map peer-reviewed literature that explicitly assesses the societal value of ESI across instrumental, intrinsic, and relational value types, and the diversity of approaches used to assess those values. Drawing from 13,823 publications acr...
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作者：Deng, Chao; Ma, Xinyi; Lu, Hui; Zhao, Hongyu; Ming, Jingsi; Wang, Tao
作者单位：Shanghai Jiao Tong University; Shanghai Jiao Tong University; Shanghai Jiao Tong University; Shanghai Jiao Tong University; Shanghai Jiao Tong University; Yale University; East China Normal University; East China Normal University
摘要：Current single-cell profiling technologies enable the capture of multiple cellular modalities, providing valuable insights into complex biological systems. While a substantial amount of single-cell multimodal data has been generated and accumulated, most of these datasets are unpaired, characterized by distinct feature spaces and a lack of cell-wise correspondence. The absence of explicit linkages between modalities poses a fundamental challenge for data integration and interpretation. To addr...
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作者：Godara, Prakhar
作者单位：New York University
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作者：Hanasaki, Noriaki; Hattori, Takayuki; Komoda, Takumi; Minamoto, Kouei; Torigoe, Shuhei; Yamashita, Satoshi; Nakazaw, Yasuhiro; Nakano, Takehito; Yoshimi, Kouhei; Yashima, Mitsuharu; Mukuda, Hidekazu; Widyaiswari, Utami; Watanabe, Isao; Koda, Akihiro; Honda, Takashi; Otomo, Toshiya; Sagayama, Hajime; Kodama, Katsuaki; Murakawa, Hiroshi; Sakai, Hideaki
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作者：Nosek, Brian A.; Allison, David B.; Jamieson, Kathleen Hall; Mcnutt, Marcia; Nielsen, A. Beau; Wolf, Susan M.
作者单位：University of Virginia; Indiana University System; Indiana University Bloomington; University of Pennsylvania; National Academies of Sciences, Engineering & Medicine; University of Minnesota System; University of Minnesota Twin Cities; University of Minnesota System; University of Minnesota Twin Cities
摘要：Vigorous debate has erupted over the trustworthiness of scientific research findings in a number of domains. The question what makes research findings trustworthy? elicits different answers depending on whether the emphasis is on research integrity and ethics, research methods, transparency, inclusion, assessment and peer review, or scholarly communication. Each provides partial insight. We offer a systems approach that focuses on whether the research is accountable, evaluable, well-formulated...
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作者：Perochon, Eddie; Guenard, Benoit; Gippet, Jerome M. W.; Klaftenberger, Tristan; Ollier, Sebastien; Bertelsmeier, Cleo
作者单位：University of Lausanne; University of Hong Kong; University of Fribourg; Universite Paris Saclay; AgroParisTech; Centre National de la Recherche Scientifique (CNRS)
摘要：Sociality has evolved several times and is a key strategy for overcoming environmental challenges and promoting ecological success. Yet, it remains unclear how environmental conditions shape global variation in social traits of animals. With their diverse societies and global distribution, ants are ideal to test whether environmental conditions influence the distribution of animal social traits worldwide. Here, we used trait data for a total of 3,299 ant species to explore how three key social...
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作者：Wells, Tyler L.; Galani, Melpomeni; Popoli, Reynaldo; Zagoraiou, Laskaro; Akay, Turgay
作者单位：Dalhousie University; Academy of Athens
摘要：Precise and adaptable movements are achieved by well-regulated muscle contractions, which are mainly governed by the excitability of motor neurons. Several neuromodulatory systems originating in the motor cortex, brainstem, and spinal cord regulate motor neuron excitability via the release of neurotransmitters such as acetylcholine and serotonin. However, these systems can have seemingly similar effects on motor neuron output, raising questions about interaction during movement. To address thi...
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作者：Decker, Colter J.; Chen, Tony G.; Yuen, Michelle C.; Wood, Robert J.
作者单位：Harvard University; University System of Georgia; Georgia Institute of Technology; Montana State University System; Montana State University Bozeman
摘要：Rolling contact joints (RCJs) guide motion in robotic linkages, including manipulators, surgical devices, prosthetics, and more. In this work, we present a generalized optimization method to tailor the kinematic properties of RCJs by simultaneously optimizing both noncircular surface geometries and internal actuation pulley shapes. Our approach accommodates multiple joint types, including passively coupled systems with programmable spring stiffness as well as actuated single or multilink mecha...
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作者：Guo, Yaru; Liu, Youxing; Li, Lu; Xu, Yachao; Lin, Zheng; Sun, Zongqiang; Luo, Mingchuan; Guo, Shaojun; Deng, Xuliang
作者单位：Peking University; Beijing University of Chemical Technology
摘要：Solar energy-driven hydrogen peroxide (H2O2) synthesis from atmospheric oxygen and water represents a sustainable and highly promising avenue for the production of this essential chemical. Covalent organic frameworks (COFs) offer a molecular platform for the direct conversion of solar energy to H2O2, however, they are persistently plagued by the recombination of photogenerated charge carriers, a phenomenon induced by sigma-bond rotation under light irradiation, which typically leads to sluggis...
