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作者：Nadav-Eliyahu, Shani; Bohrer, Chaya; Boocholez, Alon; Kinor, Noa; Aho, Vesa; Benichou, Jennifer I. C.; Mattola, Salla; Salminen, Sami; Niskanen, Henri; Kaikkonen, Minna U.; Vihinen-Ranta, Maija; Shav-Tal, Yaron
作者单位：Bar Ilan University; Bar Ilan University; University of Jyvaskyla; University of Jyvaskyla; University of Eastern Finland
摘要：Herpes simplex virus type 1 (HSV-1) infection remodels the host nucleus, marginalizing chromatin and forming viral replication compartments (VRCs). Nuclear speckles, nuclear bodies enriched in RNA-processing factors, reposition around VRCs and undergo structural changes. While viral mRNAs are transcribed in VRCs and host transcription is largely suppressed, the nuclear routes used by viral and upregulated host transcripts and their relationship with nuclear bodies remain unclear. We show that ...
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作者：Spohn, Marie; Arnillas, Carlos Alberto; Bakker, Jonathan D.; Borer, Elizabeth T.; Brathen, Kari Anne; Cadotte, Marc W.; Carbutt, Clinton; Catford, Jane A.; Dupre, Mary E.; Dwyer, Ciara; Eisenhauer, Nico; Estrada, Catalina; Hagenah, Nicole; Haider, Sylvia; Harms, Kyle E.; Hautier, Yann; Hersch-Green, Erika I.; Knops, Johannes M. H.; Laanisto, Lauri; Laungani, Ramesh; Macek, Peter; Martinson, Holly; Millett, Jonathan; Partel, Meelis; Pennings, Steven C.; Peri, Pablo L.; Power, Sally A.; Risch, Anita C.; Roscher, Christiane; Seabloom, Eric W.; Smith, Nicholas G.; Stevens, Carly; Virtanen, Risto; Wardle, Glenda M.; Zhang, Pengfei
作者单位：Swedish University of Agricultural Sciences; University of Toronto; University Toronto Scarborough; University of Washington; University of Washington Seattle; University of Minnesota System; University of Minnesota Twin Cities; UiT The Arctic University of Tromso; University of Toronto; University Toronto Scarborough; University of Kwazulu Natal; University of London; King's College London; University of Melbourne; Australian National University; Lund University; German Research Foundation (DFG); German Centre for Integrative Biodiversity Research (iDiv); Leipzig University; Imperial College London; University of Pretoria; Leuphana University Luneburg; Louisiana State University System; Louisiana State University; Utrecht University; Michigan Technological University; Xi'an Jiaotong-Liverpool University; Estonian University of Life Sciences; Czech Academy of Sciences; Biology Centre of the Czech Academy of Sciences; Loughborough University; University of Tartu; Tartu University Institute of Ecology & Earth Sciences; University of Houston System; University of Houston; Instituto Nacional de Tecnologia Agropecuaria (INTA); Western Sydney University; Swiss Federal Institutes of Technology Domain; Swiss Federal Institute for Forest, Snow & Landscape Research; Helmholtz Association; Helmholtz Center for Environmental Research (UFZ); Texas Tech University System; Texas Tech University; Lancaster University; University of Oulu; University of Sydney; Lanzhou University
摘要：The search for predictors of plant diversity has challenged scientists for decades. Here we identify intense photosynthetically active radiation (PAR) as a major factor constraining plant species richness in global grasslands. We show that the strength of the negative relationship between species richness and PAR increases with increasing elevation and that species richness is more strongly correlated with intense PAR than with UV-B radiation, climate variables, and atmospheric nitrogen deposi...
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作者：Ainsworth, Elizabeth A.; Ort, Donald R.
作者单位：University of Illinois System; University of Illinois Urbana-Champaign; University of Illinois System; University of Illinois Urbana-Champaign
摘要：Stephen Long pioneered a multidisciplinary approach to advance our knowledge of photosynthesis, by integrating research at the molecular, cellular, organismal, and ecological levels along with a pragmatic understanding of the implications for agriculture. This involved development of new mathematical models, patented equipment for analyzing photosynthetic efficiency, and the world's largest open-air laboratory for understanding crop responses to atmospheric change. Long fundamentally changed o...
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作者：Ajourlou, Parviz; Milne, Glenn A.; Love, Ryan; Afonso, Juan C.; Salajegheh, Farshad; Latychev, Konstantin; Kjeldsen, Kristian K.; Lepipas, Alexis; Martos, Yasmina M.; Woodroffe, Sarah A.
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作者：Bisot, Corentin; Galvez, Loreto Oyarte; Kahane, Felix; Van Son, Marije; Turcu, Bianca; Broekman, Rob; Lin, Kai-Kai; Bontenbal, Paco; Winter, Max Kerr; Kokkoris, Vasilis; West, Stuart A.; Godin, Christophe; Kiers, E. Toby; Shimizu, Thomas S.
作者单位：Vrije Universiteit Amsterdam; AMOLF; Ecole Normale Superieure de Lyon (ENS de LYON); Universite Lyon 1; INRAE; Centre National de la Recherche Scientifique (CNRS); University of Oxford
摘要：Symbiotic nutrient exchange between arbuscular mycorrhizal (AM) fungi and their host plants varies widely depending on their physical, chemical, and biological environment. Yet dissecting this context dependency remains challenging because we lack methods for tracking nutrients such as carbon (C) and phosphorus (P). Here, we developed an approach to quantitatively estimate C and P fluxes in the AM symbiosis from comprehensive network morphology quantification, achieved by robotic imaging and m...
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作者：Grant, Stephanie M.; Melkote, Ashvini; Bernstein, Mollie X.; Jursa, Thomas; Taylor, Cherish A.; Hutchens, Steven; Shawlot, William; Zweifel, Larry S.; Gonzales, Rueben A.; Smith, Donald R.; Mukhopadhyay, Somshuvra
作者单位：University of Texas System; University of Texas Austin; University of Washington; University of Washington Seattle; University of California System; University of California Santa Cruz; University of Texas System; University of Texas Austin
摘要：Essential metals accumulate in the basal ganglia at elevated levels and induce incurable motor disease. But, unlike other motor diseases, the neuronal targets of essential metals are unknown, and this fundamental knowledge gap has limited therapeutic progress. Because metal efflux transporters have high specificity, we hypothesized that neuron-specific knockout or knockin (i.e., overexpression) of efflux transporters may alter metal levels in targeted neurons and define the neuronal targets of...
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作者：Milks, Annemieke; Ntinou, Maria; Koutalis, Stylianos; Michailidis, Dimitrios; Konidaris, George E.; Giusti, Domenico; Thompson, Nicholas; Tsartsidou, Georgia; Panagopoulou, Eleni; Tourloukis, Vangelis; Karkanas, Panagiotis; Harvati, Katerina
作者单位：University of Reading; Aristotle University of Thessaloniki; Eberhard Karls University of Tubingen; Aristotle University of Thessaloniki; Eberhard Karls University of Tubingen; University of Ioannina; Eberhard Karls University of Tubingen; Eberhard Karls University of Tubingen
摘要：The Middle Pleistocene (MP; ca. 774 to 129 ka) marks a critical period of human evolution, characterized by increasing behavioral complexity and the first unambiguous evidence of plant-based technologies. Despite this, direct evidence for early wooden tool use remains exceptionally rare. Here, we present the earliest handheld wooden tools, identified from secure contexts at the site of Marathousa 1, Greece, dated to ca. 430 ka (MIS12). Through a systematic morphological, microscopic, taphonomi...
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作者：Paschou, Christina; Apokotou, Olympia; Charmpi, Konstantina; Kollias, Anastasios; Dede, Sofia; Samiotaki, Martina; Koutsoudaki, Paraskevi N.; Havaki, Sophia; Palese, Francesca; Dimoula, Konstantina; Emmanouilidou, Evangelia; Gorgoulis, Vassilis G.; Taoufik, Era; Zurzolo, Chiara; Matsas, Rebecca; Papastefanaki, Florentia
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作者：Wang, Bin; Zhou, Xiaoying; Loros, Jennifer J.; Dunlap, Jay C.
作者单位：Dartmouth College; Dartmouth College
摘要：The transcription factor complex White Collar Complex (WCC) functions both as a photoreceptor and as the circadian positive element. In response to light, WCC acutely activates similar to 5% of all genes, whereas in the dark it influences expression of about 40% of the transcriptome. Among WCC targets is frq, which is acutely light-activated through the pLRE (proximal Light-Response Element) and circadian-regulated through the C-box (Clock-box) promoter element that is not responsible for ligh...
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作者：Zhang, Chi; Chen, Liang; Wang, Suomin; Wang, Chao; Pan, Jianwei; Hou, Suiwen
作者单位：Lanzhou University
摘要：Stomata, specialized structures of plant epidermis, are crucial for gas (e.g., CO2, O2, and H2O) exchange between plants and the environment. Stomatal density and pattern are governed by ERECTA family (ERf) receptor-like kinases-controlled signaling. Clathrin-mediated endocytosis (CME) is a new mechanism for the internalization of receptors to activate the downstream signaling in animals. Here, we found that mutation of CME components resulted in formation of stomatal clusters and thus increas...
