6期

最新文章

• Unraveling the molecular mechanism for enhanced gas adsorption in mixed-metal MOFs via solid-state NMR spectroscopy AI翻译
  作者：Yan, Tao; Hou, Huaming; Wu, Changzong; Cai, Yuhang; Yin, Anping; Cao, Zhi; Liu, Zhong; He, Peng; Xu, Jun
  作者单位：Nankai University; Nankai University; Chinese Academy of Sciences; Institute of Coal Chemistry, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Chinese Academy of Sciences; Qinghai Institute of Salt Lakes, CAS
  摘要：The incorporation of multiple metal ions in metal-organic frameworks (MOFs) through one - pot synthesis can induce unique properties originating from specific atomic-scale spatial apportionment, but the extraction of this crucial information poses challenges. Herein, nondestructive solid-state NMR spectroscopy was used to discern the atomic-scale metal apportionment in a series of bulk Mg1-xCox-MOF-74 samples via identification and quantification of eight distinct arrangements of Mg/Co ions la...
• A macrophage- collagen fragment axis mediates subcutaneous adipose tissue remodeling in mice AI翻译
  作者：Vujicic, Milica; Broderick, Isabella; Salmantabar, Pegah; Perian, Charlene; Nilsson, Jonas; Wallem, Carina Sihlbom; Asterholm, Ingrid Wernstedt
  作者单位：University of Gothenburg; University of Gothenburg
  摘要：Efficient removal of fibrillar collagen is essential for adaptive subcutaneous adipose tissue (SAT) expansion that protects against ectopic lipid deposition during weight gain. Here, we used mice to further define the mechanism for this collagenolytic process. We show that loss of collagen type- 1 (CT1) and increased CT1-fragment levels in expanding SAT are associated with proliferation of resident M2- like macrophages that display increased CD206- mediated engagement in collagen endocytosis c...
• Family ideals in an era of low fertility AI翻译
  作者：Aassve, Arnstein; Adsera, Alicia; Chang, Paul Y.; Mencarini, Letizia; Park, Hyunjoon; Peng, Chen; Plach, Samuel; Raymo, James M.; Wang, Senhu; Yeung, Wei-Jun Jean
  作者单位：Bocconi University; Bocconi University; Princeton University; Princeton University; Harvard University; University of Pennsylvania; Princeton University; University of Tokyo; National University of Singapore; National University of Singapore; Agency for Science Technology & Research (A*STAR)
  摘要：Taking stock of individuals' perceived family ideals is particularly important in the current moment given unprecedented fertility declines and the diversification of households in advanced industrial societies. Study participants in urban China, Japan, South Korea, Singapore, the United States, Italy, Spain, and Norway were asked to evaluate vignettes describing families whose characteristics vary on ten dimensions. In contrast to previous studies that focused on a single dimension, such as f...
• Decoupling particle-impact dissipation mechanisms in 3D architected materials AI翻译
  作者：Butruille, Thomas; Crone, Joshua C.; Portela, Carlos M.
  作者单位：Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT)
  摘要：Ultralight architected materials enabled by advanced manufacturing processes have achieved density-normalized strength and stiffness properties that are inaccessible to bulk materials. However, the majority of this work has focused on static loading and elastic-wave propagation. Fundamental understanding of the mechanical behavior of architected materials under large-deformation dynamic conditions remains limited, due to the complexity of mechanical responses and shortcomings of characterizati...
• The intrinsic twinning and enigmatic twisting of aragonite crystals AI翻译
  作者：Gavryushkin, Pavel N.; Recnik, Aleksander; Donskikh, Katerina G.; V. Banaev, Maksim; Sagatov, Nursultan E.; Rashchenko, Sergey; Volkov, Sergey; Aksenov, Sergey; Mikhailenko, Denis; Korsakov, Andrey; Daneu, Nina; Litasov, Konstantin D.
  作者单位：Russian Academy of Sciences; Siberian Branch of the Russian Academy of Sciences; Sobolev Institute of Geology & Mineralogy of the Russian Academy of Sciences; Novosibirsk State University; Slovenian Academy of Sciences & Arts (SASA); Jozef Stefan Institute; Russian Academy of Sciences; Kola Science Centre of the Russian Academy of Sciences; Russian Academy of Sciences; Slovenian Academy of Sciences & Arts (SASA); Jozef Stefan Institute; Vereshchagin Institute of High Pressure Physics, Russian Academy of Sciences; Russian Academy of Sciences
  摘要：It is generally accepted that aragonite crystals of biogenic origin are characterized by significantly higher twin densities compared to samples formed during geological processes. Based on our single crystal X-ray diffraction (SCXRD) and transmission electron microscopy (TEM) study of aragonite crystals from various localities, we show that in geological aragonites, the twin densities are comparable to those of the samples from crossed lamellar zones of molluscs shells. The high twin density ...
• Light controls mesophyll- specific posttranscriptional splicing of photoregulatory genes by AtPRMT5 AI翻译
  作者：Yan, Yan; Luo, Haofei; Qin, Yuwei; Yan, Tingting; Jia, Jinbu; Hou, Yifeng; Liu, Zhijian; Zhai, Jixian; Long, Yanping; Deng, Xian; Cao, Xiaofeng
  作者单位：Chinese Academy of Sciences; Institute of Genetics & Developmental Biology, CAS; Chinese Academy of Sciences; Institute of Genetics & Developmental Biology, CAS; Southern University of Science & Technology; Hainan Academy of Agricultural Sciences; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS
  摘要：Light plays a central role in plant growth and development, providing an energy source and governing various aspects of plant morphology. Previous study showed that many polyadenylated full- length RNA molecules within the nucleus contain unspliced introns (post- transcriptionally spliced introns, PTS introns), which may play a role in rapidly responding to changes in environmental signals. However, the mechanism underlying post- transcriptional regulation during initial light exposure of youn...
• Spatial configuration of Fe-Co dual- sites boosting catalytic intermediates coupling toward oxygen evolution reaction AI翻译
  作者：Zhang, Taiyan; Jiang, Jingjing; Sun, Wenming; Gong, Shuyan; Liu, Xiangwen; Tian, Yang; Wang, Dingsheng
  作者单位：Capital Normal University; Beijing Academy of Science & Technology; Tsinghua University
  摘要：Oxygen evolution reaction (OER) is the pivotal obstacle of water splitting for hydrogen production. Dual - sites catalysts (DSCs) are considered exceeding single - site catalysts due to the preternatural synergetic effects of two metals in OER. However, appointing the specific spatial configuration of dual - sites toward more efficient catalysis still remains a challenge. Herein, we constructed two configurations of Fe-Co dual- sites: stereo Fe-Co sites (stereo - Fe - Co DSC) and planar Fe-Co ...
• The ubiquitin E3 ligase BFAR promotes degradation of PNPLA3 AI翻译
  作者：Das, Avash; Cheng, Haili; Wang, Yang; Kinch, Lisa N.; Liang, Guosheng; Hong, Sen; Hobbs, Helen H.; Cohen, Jonathan C.
  作者单位：University of Texas System; University of Texas Southwestern Medical Center; Howard Hughes Medical Institute; University of Texas System; University of Texas Southwestern Medical Center; University of Texas System; University of Texas Southwestern Medical Center
  摘要：A missense variant in patatin-like phospholipase domain- containing protein 3 [PNPLA3(I148M)] is the most impactful genetic risk factor for fatty liver disease (FLD). We previously showed that PNPLA3 is ubiquitylated and subsequently degraded by proteasomes and autophagosomes and that the PNPLA3(148M) variant interferes with this process. To define the machinery responsible for PNPLA3 turnover, we used small interfering (si)RNAs to inactivate components of the ubiquitin proteasome system. Inac...
• Transfer learning to leverage larger datasets for improved prediction of protein stability changes AI翻译
  作者：Dieckhaus, Henry; Brocidiacono, Michael; Randolph, Nicholas Z.; Kuhlman, Brian
  作者单位：University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine
  摘要：Amino acid mutations that lower a protein's thermodynamic stability are implicated in numerous diseases, and engineered proteins with enhanced stability can be important in research and medicine. Computational methods for predicting how mutations perturb protein stability are, therefore, of great interest. Despite recent advancements in protein design using deep learning, in silico prediction of stability changes has remained challenging, in part due to a lack of large, high- quality training ...
• Improved atmospheric constraints on Southern Ocean CO2 exchange AI翻译
  作者：Jin, Yuming; Keeling, Ralph F.; Stephens, Britton B.; Long, Matthew C.; Patra, Prabir K.; Roedenbeck, Christian; Morgan, Eric J.; Kort, Eric A.; Sweeney, Colm
  作者单位：University of California System; University of California San Diego; Scripps Institution of Oceanography; National Center Atmospheric Research (NCAR) - USA; National Center Atmospheric Research (NCAR) - USA; Japan Agency for Marine-Earth Science & Technology (JAMSTEC); Max Planck Society; University of Michigan System; University of Michigan; National Oceanic Atmospheric Admin (NOAA) - USA
  摘要：We present improved estimates of air-sea CO2 exchange over three latitude bands of the Southern Ocean using atmospheric CO2 measurements from global airborne campaigns and an atmospheric 4 - box inverse model based on a mass- indexed isentropic coordinate (M theta e). These flux estimates show two features not clearly resolved in previous estimates based on inverting surface CO2 measurements: a weak winter - time outgassing in the polar region and a sharp phase transition of the seasonal flux ...