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作者：Li, Yanxiao; Zhang, Dongpeng; Wang, Pengfei; Qu, Jinyong; Zhan, Sihui
作者单位：Nankai University
摘要：Water resources are indispensable basic resources and important environmental carriers; the presence of organic contaminants in wastewater poses considerable risks to the health of both humans and ecosystems. Although the Fenton- like reactions using H2O2 as the oxidant to destroy organic pollutants are attractive, there are still challenges in improving reaction activity under neutral or even alkaline conditions. Herein, we designed a H2O2 activation pathway with O 2 center dot- as the main a...
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作者：Ross, Stephen L.; Jiang, Shangyue; Young, Michael F.; Meyer, Joanna L.; Strambler, Michael J.
作者单位：University of Connecticut; National Bureau of Economic Research; University of Connecticut; Yale University
摘要：While studies have examined the effects of schools offering in- person learning during the pandemic, this study provides analysis of student enrollment decisions (remote versus in- person) in response to schools providing in- person learning opportunities. In Connecticut during the 2020-21 school year, we find that student take- up of in- person learning opportunities was low with students on average enrolled in- person for only half of the days offered, and take- up was even lower in schools ...
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作者：Valentino, Isabella M.; Llivicota-Guaman, Jeniffer G.; Dao, Thuy P.; Mulvey, Erin O.; Lehman, Andrew M.; Galagedera, Sarasi K. K.; Mallon, Erica L.; Castaneda, Carlos A.; Kraut, Daniel A.
作者单位：Villanova University; Syracuse University
摘要：Ubiquitination is one of the most common posttranslational modifications in eukaryotic cells. Depending on the architecture of polyubiquitin chains, substrate proteins can meet different cellular fates, but our understanding of how chain linkage controls protein fate proteins and to the proteasome or other protein quality control machinery elements and play a role in substrate fate determination. Under physiological conditions, UBQLN2 forms biomolecular condensates through phase separation, a ...
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作者：Zhang, Oumeng; Alcalde, Reinaldo E.; Zhou, Haowen; Yin, Siyuan; Newman, Dianne K.; Yang, Changhuei
作者单位：California Institute of Technology; California Institute of Technology; California Institute of Technology
摘要：Microbial interactions in the rhizosphere contribute to soil health, making understanding these interactions crucial for sustainable agriculture and ecosystem management. Yet it is difficult to understand what we cannot see; among the limitations in rhizosphere imaging are challenges associated with rapidly and noninvasively imaging microbial cells over field depths relevant to plant roots. Here, we present a bimodal imaging technique called complex- field and fluorescence microscopy using the...
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作者：Guzikevits, Mika; Gordon-Hecker, Tom; Rekhtman, David; Salameh, Shaden; Israel, Salomon; Shayo, Moses; Gozal, David; Perry, Anat; Gileles-Hillel, Alex; Choshen-Hillel, Shoham
作者单位：Hebrew University of Jerusalem; Hebrew University of Jerusalem; Ben-Gurion University of the Negev; Hebrew University of Jerusalem; Hadassah University Hospital; Hebrew University of Jerusalem; Hebrew University of Jerusalem; University of London; King's College London; University of Missouri System; University of Missouri Columbia; Marshall University; Hebrew University of Jerusalem; Hadassah University Hospital; Hebrew University of Jerusalem
摘要：In the pursuit of mental and physical health, effective pain management stands as a cornerstone. Here, we examine a potential sex bias in pain management. Leveraging insights from psychological research showing that females' pain is stereotypically judged as less intense than males' pain, we hypothesize that there may be tangible differences in pain management decisions based on patients' sex. Our investigation spans emergency department (ED) datasets from two countries, including discharge no...
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作者：von Hohenberg, Bernhard Clemm; Hager, Anselm
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作者：Wolf, Harald
作者单位：Ulm University
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作者：Dorfschmidt, Lena; Vasa, Frantisek; White, Simon R.; Romero-Garcia, Rafael; Kitzbichler, Manfred G.; Alexander-Bloch, Aaron; Cieslak, Matthew; Mehta, Kahini; Satterthwaite, Theodore D.; Bethlehem, Richard A. I.; Seidlitz, Jakob; Vertes, Petra E.; Bullmore, Edward T.
作者单位：University of Cambridge; University of Pennsylvania; University of Pennsylvania; Pennsylvania Medicine; Childrens Hospital of Philadelphia; University of Pennsylvania; Pennsylvania Medicine; University of London; King's College London; Consejo Superior de Investigaciones Cientificas (CSIC); CIBER - Centro de Investigacion Biomedica en Red; CIBERSAM; University of Sevilla; Virgen del Rocio University Hospital; University of Cambridge; University of Cambridge; University of Pennsylvania; Pennsylvania Medicine; Childrens Hospital of Philadelphia; University of Pennsylvania; University of Cambridge
摘要：Adolescent development of human brain structural and functional networks is increasingly recognized as fundamental to emergence of typical and atypical adult cognitive and emotional processes. We analysed multimodal magnetic resonance imaging (MRI) data collected from N similar to 300 healthy adolescents (51%; female; 14 to 26 y) each scanned repeatedly in an accelerated longitudinal design, to provide an analyzable dataset of 469 structural scans and 448 functional MRI scans. We estimated the...
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作者：Rockey, Nicole C.; Le Sage, Valerie; Shephard, Meredith; Vargas-Maldonado, Nahara; Vu, Michelle N.; Brown, Cambria A.; Patel, Krishna; French, Andrea J.; Merrbach, Grace A.; Walter, Sydney; Ferreri, Lucas M.; Holmes, Katie E.; Vaninsberghe, David; Clack, Herek L.; Prussin II, Aaron J.; Lowen, Anice C.; Marr, Linsey C.; Lakdawala, Seema S.
作者单位：Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Emory University; University of Michigan System; University of Michigan; Virginia Polytechnic Institute & State University; Duke University
摘要：Sustained community spread of influenza viruses relies on efficient person-to-person transmission. Current experimental transmission systems do not mimic environmental conditions (e.g., air exchange rates, flow patterns), host behaviors, or exposure durations relevant to real- world settings. Therefore, results from these traditional systems may not be representative of influenza virus transmission in humans. To address this pitfall, we developed a close-range transmission setup that implement...
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作者：Yuan, Xueying; Yan, Lu; Chen, Qinfu; Zhu, Shukai; Zhou, Xinyu; Zeng, Ling - Hui; Liu, Mingjie; He, Xiaojing; Huang, Jun; Lu, Weiguo; Zhang, Long; Yan, Haiyan; Wang, Fangwei
作者单位：Zhejiang University; Zhejiang University; Hangzhou City University; Huazhong University of Science & Technology; Zhejiang University; Zhejiang University; Zhejiang University; Zhejiang University; Zhejiang University; Zhejiang University; Zhejiang University
摘要：The ring- shaped Cohesin complex, consisting of core subunits Smc1, Smc3, Scc1, and SA2 (or its paralog SA1), topologically entraps two duplicated sister DNA molecules to establish sister chromatid cohesion in S- phase. It remains largely elusive how the Cohesin release factor Wapl binds the Cohesin complex, thereby inducing Cohesin disassociation from mitotic chromosomes to allow proper resolution and separation of sister chromatids. Here, we show that Wapl uses two structural modules contain...
