作者：Liang, Shuang; Wu, Qi; Wang, Changhua; Wang, Rui; Li, Dashuai; Xing, Yanmei; Jin, Dexin; Ma, He; Liu, Yichun; Zhang, Peng; Zhang, Xintong
作者单位：Northeast Normal University - China; Dalhousie University
摘要：Clean production of hydrogen peroxide (H2O2) with water, oxygen, and renewable energy is considered an important green synthesis route, offering a valuable substitute for the traditional anthraquinone method. Currently, renewable energy-driven production of H2O2 mostly relies on soluble additives, such as electrolytes and sacrificial agents, inevitably compromising the purity and sustainability of H2O2. Herein, we develop a solution plasma catalysis technique that eliminates the need for solub...
作者：Ryu, Eunjin; Yoo, Juyeong; Kang, Mi-Sun; Ha, Na Young; Jang, Yewon; Kim, Jinwoo; Kim, Yeongjae; Kim, Byung-Gyu; Kim, Shinseog; Myung, Kyungjae; Kang, Sukhyun
作者单位：Institute for Basic Science - Korea (IBS); Ulsan National Institute of Science & Technology (UNIST); Ulsan National Institute of Science & Technology (UNIST); Harvard University; Harvard Medical School
摘要：Ubiquitination status of proliferating cell nuclear antigen (PCNA) is crucial for regulating DNA lesion bypass. After the resolution of fork stalling, PCNA is subsequently deubiquitinated, but the underlying mechanism remains undefined. We found that the DNA- loaded Ub-PCNA through distinct DNA- binding and PCNA- binding motifs. facilitating the deubiquitination of DNA- loaded Ub-PCNA. ATAD5 also enhances the Ub-PCNA deubiquitination by USP7 and USP11 through specific interactions. had increas...
