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作者：Eisinger-Mathason, T. S. Karin; Mucaj, Vera; Biju, Kevin M.; Nakazawa, Michael S.; Gohil, Mercy; Cash, Timothy P.; Yoon, Sam S.; Skuli, Nicolas; Park, Kyung Min; Gerecht, Sharon; Simon, M. Celeste
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作者：Nam, Shinjae; Riegel, Elisabeth; Hoermann, Lukas; Hofmann, Oliver T.; Gretz, Oliver; Weymouth, Alfred J.; Giessibl, Franz J.
作者单位：University of Regensburg; Graz University of Technology
摘要：Atomic force microscopy with a CO- functionalized tip can be used to directly image the internal structure of a planar molecule and to characterize chemical bonds. However, hydrogen atoms usually cannot be directly observed due to their small size. At the same time, these atoms are highly important, since they can direct on- surface chemical reactions. Measuring in-plane interactions at the sides of PTCDA (3,4,9,10- perylenetetracarboxylic dianhydride) molecules with lateral force microscopy a...
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作者：Kakuda, Keita; Ikenaka, Kensuke; Kuma, Akiko; Doi, Junko; Aguirre, Cesar; Wang, Nan; Ajiki, Takahiro; Choong, Chi- Jing; Kimura, Yasuyoshi; Badawy, Shaymaa Mohamed Mohamed; Shima, Takayuki; Nakamura, Shuhei; Baba, Kousuke; Nagano, Seiichi; Nagai, Yoshitaka; Yoshimori, Tamotsu; Mochizuki, Hideki
作者单位：University of Osaka; University of Osaka; Egyptian Knowledge Bank (EKB); Zagazig University; Nara Medical University; University of Osaka
摘要：The neuron - to- neuronpropagation of misfolded alpha-synuclein (alpha Syn) aggregates is thought to be key to the pathogenesis of synucleinopathies. Recent studies have shown that extracellular alpha Syn aggregates taken up by the endosomal-lysosomal system can rupture the lysosomal vesicular membrane; however, it remains unclear whether lysosomal rupture leads to the transmission of alpha Syn aggregation. Here, we applied cell -based alpha Syn propagation models to show that ruptured lysosom...
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作者：Bonetti, Pietro M.; Christos, Maine; Sachdev, Subir
作者单位：Harvard University
摘要：A long-standing problem in the study of the under-hole-doped cuprates has been the description of the Fermi surfaces underlying the high magnetic field quantum oscillations, and their connection to the higher temperature pseudogap metal. Harrison and Sebastian [ Phys. Rev. Lett. 106, 226402 (2011)] proposed that the pseudogap Fermi arcs are reconstructed into an electron pocket by field-induced charge density wave order. But computations on such a model [Zhang and Mei, Europhys. Lett. 114, 470...
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作者：Khalilian-Gourtani, Amirhossein; Wang, Ran; Chen, Xupeng; Yu, Leyao; Dugan, Patricia; Friedman, Daniel; Doyle, Werner; Devinsky, Orrin; Wang, Yao; Flinker, Adeen
作者单位：New York University; New York University; New York University; New York University
摘要：When we vocalize, our brain distinguishes self-generated sounds from external ones. A corollary discharge signal supports this function in animals; however, in humans, its exact origin and temporal dynamics remain unknown. We report electrocorticographic recordings in neurosurgical patients and a connectivity analysis framework based on Granger causality that reveals major neural communications. We find a reproducible source for corollary discharge across multiple speech production paradigms l...
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作者：Marquet, Pablo A.; Gaxiola, Aurora
作者单位：Pontificia Universidad Catolica de Chile; Universidad de Chile; Pontificia Universidad Catolica de Chile; The Santa Fe Institute
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作者：Chiba-Okab, Hiroaki; Plotkin, Joshua B.
作者单位：University of Pennsylvania; University of Pennsylvania; University of Pennsylvania
摘要：Traditional models of social learning by imitation are based on simple contagion- where an individual may imitate a more successful neighbor following a single interaction. But real-world contagion processes are often complex, meaning that multiple exposures may be required before an individual considers changing their type. We introduce a framework that combines the concepts of simple payoff-biased imitation with complex contagion, to describe how social behaviors spread through a population....
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作者：Barone, Benedetto
作者单位：University of Hawaii System; University of Hawaii Manoa; University of Hawaii System; University of Hawaii Manoa
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作者：Du, Samuel W.; Newby, Gregory A.; Salom, David; Gao, Fangyuan; Menezes, Carolline Rodrigues; Suh, Susie; Choi, Elliot H.; Chen, Paul Z.; Liu, David R.; Palczewski, Krzysztof
作者单位：University of California System; University of California Irvine; University of California System; University of California Irvine; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Harvard University; Harvard University; Johns Hopkins University; Johns Hopkins University; Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); University of California System; University of California Irvine; University of California System; University of California Irvine
摘要：Rhodopsin, the prototypical class- A G- protein coupled receptor, is a highly sensitive receptor for light that enables phototransduction in rod photoreceptors. Rhodopsin plays not only a sensory role but also a structural role as a major component of the rod outer segment disc, comprising over 90% of the protein content of the disc membrane. Mutations in RHO which lead to structural or functional abnormalities, including the autosomal recessive E150K mutation, result in rod dysfunction and de...
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作者：Hou, Qiang; Wei, Wei; Zhou, Xin; Liu, Wenhui; Wang, Ke; Xing, Xiangzhuo; Zhang, Yufeng; Zhou, Nan; Pan, Yongqiang; Sun, Yue; Shi, Zhixiang
作者单位：Southeast University - China; Qufu Normal University; Jiangsu University; Chinese Academy of Sciences; Hefei Institutes of Physical Science, CAS
摘要：Recent investigations of FeSe-based superconductors have revealed the presence of two superconducting domes and suggest possible distinct pairing mechanisms. Two superconducting domes are commonly found in unconventional superconductors and exhibit unique normal states and electronic structures. In this study, we conducted electromagnetic transport measurements to establish a complete phase diagram, successfully observing the two superconducting domes in FeSe1-xSx (0 <= x <= 0.25) and FeSe1-xT...
