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作者：Takeshita, Rafaela S. C.
作者单位：University System of Ohio; Kent State University; Kent State University Salem; Kent State University Kent; University System of Ohio; Kent State University; Kent State University Salem; Kent State University Kent
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作者：Kroning, Kayla; Gannot, Noam; Li, Xingyu; Putansu, Aubrey; Zhou, Guanwei; Sescil, Jennifer; Shen, Jiaqi; Wilson, Avery; Fiel, Hailey; Li, Peng; Wang, Wenjing
作者单位：University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan
摘要：G protein - coupled receptors (GPCRs) transduce the effects of many neuromodulators including dopamine, serotonin, epinephrine, acetylcholine, and opioids. The localization of synthetic or endogenous GPCR agonists impacts their action on specific neuronal pathways. In this paper, we show a series of single - protein chain integrator sensors that are highly modular and could potentially be used to determine GPCR agonist localization across the brain. We previously engineered integrator sensors ...
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作者：Xu, Qicheng; Zhang, He; Vandenkoornhuyse, Philippe; Guo, Shiwei; Kuzyakov, Yakov; Shen, Qirong; Ling, Ning
作者单位：Nanjing Agricultural University; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Ecology & Environment (INEE); Universite de Rennes; Lanzhou University; University of Gottingen; University of Gottingen
摘要：Organic carbon availability in soil is crucial for shaping microbial communities, yet, uncertainties persist concerning microbial adaptations to carbon levels and the ensuing ecological and evolutionary consequences. We investigated organic carbon metabolism, antibiotic resistance, and virus-host interactions in soils subjected to 40 y of chemical and organic fertilization that led to contrasting carbon availability: carbonpoor and carbonrich soils, respectively. Carbon - poor soils drove the ...
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作者：Emanuel, Kerry
作者单位：Massachusetts Institute of Technology (MIT)
摘要：Cyclone Jasper struck northern Queensland in mid- December, 2023, causing extensive flooding stemming from torrential rain. Many stations reported rainfall totals exceeding 1 m, and a few surpassed 2 m, possibly making Jasper the wettest tropical cyclone in Australian history. To be better prepared for events like Jasper, it is useful to estimate the probability of rainfall events of Jasper's magnitude and how that probability is likely to evolve as climate warms. To make such estimates, we ap...
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作者：Yang, Bin; Intoy, Janis; Rucci, Michele
作者单位：University of Rochester; University of Rochester
摘要：Humans blink their eyes frequently during normal viewing, more often than it seems necessary for keeping the cornea well lubricated. Since the closure of the eyelid disrupts the image on the retina, eye blinks are commonly assumed to be detrimental to visual processing. However, blinks also provide luminance transients rich in spatial information to neural pathways highly sensitive to temporal changes. Here, we report that the luminance modulations from blinks enhance visual sensitivity. By co...
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作者：Seas, Andreas; Noor, M. Sohail; Choi, Ki Sueng; Veerakumar, Ashan; Obatusin, Mosadoluwa; Dahill-Fuchel, Jacob; Tiruvadi, Vineet; Xu, Elisa; Riva-Posse, Patricio; Rozell, Christopher J.; Mayberg, Helen S.; Mcintyre, Cameron C.; Waters, Allison C.; Howell, Bryan
作者单位：Duke University; Duke University; University System of Ohio; Case Western Reserve University; Icahn School of Medicine at Mount Sinai; Emory University; University System of Georgia; Georgia Institute of Technology
摘要：Subcallosal cingulate (SCC) deep brain stimulation (DBS) is an emerging therapy for responsible for driving this response. Individualized biophysical models were built to achieve selective engagement of two target bundles: either the forceps minor (FM) or cingulum bundle (CB). Unilateral 2 Hz stimulation was performed in seven patients with treatment- resistant depression who responded to SCC DBS, and EPs were recorded using 256- sensor scalp electroencephalography. Two distinct EPs were obser...
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作者：Kim, Hong Ji; Lux, Byeol Kim; Lee, Eunjin; Finn, Emily S.; Woo, Choong- Wan
作者单位：Institute for Basic Science - Korea (IBS); Sungkyunkwan University (SKKU); Sungkyunkwan University (SKKU); Dartmouth College
摘要：The contents and dynamics of spontaneous thought are important factors for personality traits and mental health. However, assessing spontaneous thoughts is challenging due to their unconstrained nature, and directing participants' attention to report their thoughts may fundamentally alter them. Here, we aimed to decode two key content dimensions of spontaneous thought-self- relevance and valence-directly from brain activity. To train functional MRI-based predictive models, we used individually...
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作者：Long, Benedict Michael; Matsuda, Yusuke; Moroney, James V.
作者单位：University of Newcastle; Kwansei Gakuin University; Louisiana State University System; Louisiana State University
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作者：Mantilla, Alexander B. C.; Wang, Chih-Feng; Krayev, Andrey; Gu, Yi; Schultz, Zachary D.; El-Khoury, Patrick Z.
作者单位：Washington State University; United States Department of Energy (DOE); Pacific Northwest National Laboratory; University System of Ohio; Ohio State University
摘要：Chemical transformations near plasmonic metals have attracted increasing attention in the past few years. Specifically, reactions occurring within plasmonic nanojunctions that can be detected via surface and tip- enhanced Raman (SER and TER) scattering were the focus of numerous reports. In this context, even though the transition between localized and nonlocal (quantum) plasmons at nanojunctions is documented, its implications on plasmonic chemistry remain poorly understood. We explore the la...
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作者：Mao, Li; Quan, Zhuo; Liu, Zhi- Sheng; Huang, Chun- Hua; Wang, Zi- Han; Tang, Tian- Shu; Li, Pei- Lin; Shao, Jie; Liu, Ya- Jun; Zhu, Ben- Zhan
作者单位：Chinese Academy of Sciences; Research Center for Eco-Environmental Sciences (RCEES), CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Beijing Normal University; Beijing Normal University; Beijing University of Chemical Technology
摘要：It is well-known that highly reactive hydroxyl radicals (HO center dot) can be produced by the classic Fenton system and our recently discovered haloquinone/H2O2 system, but rarely from thiol- derivatives. Here, we found, unexpectedly, that HO center dot can be generated from H2O2 and thiourea dioxide (TUO2), a widely used and environmentally friendly bleaching agent. A carbon- centered radical and sulfite were detected and identified as the transient intermediates, and urea and sulfate as the...
