2024

最新文章

• Thermally stable high- loading single Cu sites on ZSM-5 for selective catalytic oxidation of NH3 AI翻译
  作者：Chen, Lu; Guan, Xuze; Wu, Xinbang; Asakura, Hiroyuki; Hopkinson, David G.; Allen, Christopher; Callison, June; Dyson, Paul J.; Wang, Feng Ryan
  作者单位：University of London; University College London; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Kindai University (Kinki University); Diamond Light Source; University of Oxford; UK Research & Innovation (UKRI); Science & Technology Facilities Council (STFC); STFC Rutherford Appleton Laboratory
  摘要：Rigorous comparisons between single site- and nanoparticle (NP)- dispersed catalysts featuring the same composition, in terms of activity, selectivity, and reaction mechanism, are limited. This limitation is partly due to the tendency of single metal atoms to sinter into aggregated NPs at high loadings and elevated temperatures, driven by a decrease in metal surface free energy. Here, we have developed a unique two- step method for the synthesis of single Cu sites on ZSM-5 (termed CuS/ZSM-5) w...
• Transport coefficient approach for characterizing nonequilibrium dynamics in soft matter AI翻译
  作者：He, HongRui; Liang, Heyi; Chu, Miaoqi; Jiang, Zhang; de Pablo, Juan J.; Tirrell, Matthew, V; Narayanan, Suresh; Chen, Wei
  作者单位：United States Department of Energy (DOE); Argonne National Laboratory; United States Department of Energy (DOE); Argonne National Laboratory; University of Chicago; United States Department of Energy (DOE); Argonne National Laboratory
  摘要：Nonequilibrium states in soft condensed matter require a systematic approach to characterize and model materials, enhancing predictability and applications. Among the tools, X-ray photon correlation spectroscopy (XPCS) provides exceptional temporal and spatial resolution to extract dynamic insight into the properties of the material. However, existing models might overlook intricate details. We introduce an approach for extracting the transport coefficient, denoted as J(t), from the XPCS studi...
• Reply to Moore et al.: Manipulation adherence and baseline AI attitudes as moderators of the effect of God salience on algorithm aversion AI翻译
  作者：Karatas, Mustafa; Cutright, Keisha M.
  作者单位：Nazarbayev University; Duke University
• Dietary supplementation of vitamin B1 prevents the pathogenesis of osteoarthritis AI翻译
  作者：Shen, Shuying; Liang, Yi; Zhao, Yuening; Hu, Ziang; Huang, Youling; Wu, Yizheng; Liu, Yufei; Fan, Shunwu; Wang, Qingqing; Xiao, Peng
  作者单位：Zhejiang University; Zhejiang University; Zhejiang University
  摘要：As the primary cause for chronic pain and disability in elderly individuals, osteoarthritis (OA) is one of the fastest- growing diseases due to the aging world population. To date, the impact of microenvironmental changes on the pathogenesis of OA remains poorly understood, greatly hindering the development of effective therapeutic approaches against OA. In this study, we profiled the differential metabolites in the synovial fluid from OA patients and identified the downregulation of vitamin B...
• STING trafficking activates MAPK-CREB signaling to trigger regulatory T cell differentiation AI翻译
  作者：Lin, Wei; Szaboa, Claudia; Liu, Tao; Tao, Huangheng; Wu, Xianfang; Wu, Jianjun
  作者单位：Cleveland Clinic Foundation; Cleveland Clinic Foundation
  摘要：The Type- I interferon (IFN-I)- I) response is the major outcome of stimulator of interferon genes (STING) activation in innate cells. STING is more abundantly expressed in adaptive T cells; nevertheless, its intrinsic function in T cells remains unclear. Intriguingly, we previously demonstrated that STING activation in T cells activates widespread IFN-- independent activities, which stands in contrast to the well- known STING-- mediated IFN response. Here, we have identified that STING activa...
• Pia- FLOW: Deciphering hemodynamic maps of the pial vascular connectome and its to arterial occlusion AI翻译
  作者：Gluck, Chaim; Zhou, Quanyu; Droux, Jeanne; Chen, Zhenyue; Glandorf, Lukas; Wegener, Susanne; Razansky, Daniel; Weber, Bruno; El Amki, Mohamad
  作者单位：University of Zurich; University of Zurich; Swiss Federal Institutes of Technology Domain; ETH Zurich; Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Zurich; University Zurich Hospital; University of Zurich
  摘要：The pial vasculature is the sole source of blood supply to the neocortex. The brain is contained within the skull, a vascularized bone marrow with a unique anatomical connection to the brain meninges. Recent developments in tissue clearing have enabled detailed mapping of the entire pial and calvarial vasculature. However, what are the absolute flow rate values of those vascular networks? This information cannot accurately be retrieved with the commonly used bioimaging methods. Here, we introd...
• Activity of DNA polymerase κ across the genome in human fibroblasts AI翻译
  作者：Torres, Mariela C.; Rebok, Abbey; Sun, Dongxiao; Spratt, Thomas E.
  作者单位：Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Penn State Health; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Penn State Health; University of North Carolina; University of North Carolina Chapel Hill
  摘要：DNA polymerase kappa (Pol kappa ) is a specialized polymerase that has multiple cellular roles such as translesion DNA synthesis, replication of repetitive sequences, and nucleotide excision repair. We have developed a method for capturing DNA synthesized by Pol kappa utilizing a Pol kappa -specific substrate, N 2- (4- ethynylbenzyl)- 2 '- deoxyguanosine (EBndG). After shearing of the DNA into 200 to 500 bp lengths, the EBndG- containing DNA was covalently bound to biotin using the Cu(I)- cata...
• The causal effect of mental health on labor market outcomes: The case of stress- related mental disorders following a human- made disaster AI翻译
  作者：Andersen, Signe Hald; Richmond-Rakerd, Leah S.; Moffitt, Terrie E.; Caspi, Avshalom; Glymour, Medellena M.
  作者单位：University of Michigan System; University of Michigan; Duke University; Duke University; University of London; King's College London; University of Oslo
  摘要：As disasters increase due to climate change, population density, epidemics, and technology, information is needed about postdisaster consequences for people's mental health and how stress- related mental disorders affect multiple spheres of life, including labor- market attachment. We tested the causal hypothesis that individuals who developed stress- related mental disorders as a consequence of their disaster exposure experienced subsequent weak labor- market attachment and poor work- related...
• Superior sodiophilicity and molecule crowding of crown ether boost the electrochemical performance of all- climate sodium- ion batteries AI翻译
  作者：Yao, Qian; Zheng, Cheng; Ji, Deluo; Du, Yingzhe; Su, Jie; Wang, Nana; Yang, Jian; Dou, Shixue; Qian, Yitai
  作者单位：Shandong University; University of Wollongong; University of Shanghai for Science & Technology
  摘要：Sodium - ion batteries (SIBs) as one of the promising alternatives to lithium - ion batteries have achieved remarkable progress in the past. However, the all - climate performance is still very challenging for SIBs. Herein, 15 - Crown - 5 (15 - C - 5) is screened as an electrolyte additive from a number of ether molecules theoretically. The good sodiophilicity, high molecule rigidity, and bulky size enable it to reshape the solvation sheath and promote the anion engagement in the solvated stru...
• CaMKII autophosphorylation is the only enzymatic event required for synaptic memory AI翻译
  作者：Chen, Xiumin; Cai, Qixu; Zhou, Jing; Pleasure, Samuel J.; Schulman, Howard; Zhang, Mingjie; Nicoll, Roger A.
  作者单位：Soochow University - China; Soochow University - China; University of California System; University of California San Francisco; Hong Kong University of Science & Technology; Xiamen University; University of California System; University of California San Francisco; Stanford University; Southern University of Science & Technology
  摘要：Ca 2+ /calmodulin (CaM) - dependent kinase II (CaMKII) plays a critical role in long - term potentiation (LTP), a well - established model for learning and memory through the enhancement of synaptic transmission. Biochemical studies indicate that CaMKII catalyzes a phosphotransferase (kinase) reaction of both itself (autophosphorylation) and of multiple downstream target proteins. However, whether either type of phosphorylation plays any role in the synaptic enhancing action of CaMKII remains ...