-
作者:Soh, Won-Chang; Park, Sang-Moo; Park, Jeong-Su; Karabulut, Hatice; Kang, Hee-Tae; Kang, Sun-Kyoung; Kim, Min-Sang; Park, Jihwan; Lee, Sunjae; Kim, Hye-Ran; Jun, Chang-Duk
作者单位:Gwangju Institute of Science & Technology (GIST); Gwangju Institute of Science & Technology (GIST); National Cancer Center - Korea (NCC)
摘要:Microvilli on T cells differ from those on epithelial cells, exhibiting filopodia-like characteristics that facilitate the clustering of molecules essential for sensing and cell migration. Recently, they have also been recognized as the structures from which T cell immunological synaptosomes (TIS) are released. In this study, we examined a key determinant of microvilli organization during T cell development and explored the functional roles of these structures, particularly in relation to T ce...
-
作者:Bender, Andrew; Zhao, Chong; Vogel, Edward; Awh, Edward; Voytek, Bradley
作者单位:University of California System; University of California San Diego; University of Chicago; University of Chicago; University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California San Diego
摘要:Decades of research have shown working memory (WM) relies on sustained prefrontal cortical activity and visual extrastriate activity, particularly in the alpha (8 to 12 Hz) frequency range. This alpha activity tracks the spatial location of WM items, even when spatial position is task-irrelevant and no stimulus is currently being presented. Traditional analyses of putative oscillations using bandpass filters, however, conflate oscillations with nonoscillatory aperiodic activity. Here, we reana...
-
作者:Carey, John
-
作者:Salazar-Miranda, Arianna; Fan, Zhuangyuan; Baick, Michael; Hampton, Keith N.; Duarte, Fabio; Loo, Becky P. Y.; Glaeser, Edward; Ratti, Carlo
作者单位:Yale University; University of Hong Kong; Michigan State University; Massachusetts Institute of Technology (MIT); Harvard University; Polytechnic University of Milan
摘要:We analyze changes in pedestrian behavior over a 30-y period in four urban public spaces located in New York, Boston, and Philadelphia. Building on William Whyte's observational work, which involved manual video analysis of pedestrian behaviors, we employ computer vision and deep learning techniques to examine video footage from 1979-80 and 2008-10. Our analysis measures changes in walking speed, lingering behavior, group sizes, and group formation. We find that the average walking speed has i...
-
作者:Wilke, Claus O.; Vieira, Luiz C.
作者单位:University of Texas System; University of Texas Austin
-
作者:Yang, Bao; Wang, Xuelian
作者单位:Nanjing University; Chinese Academy of Sciences
-
作者:Cho, Yongick; Jacobs, William M.
作者单位:Princeton University
摘要:Coupling between chemical fuel consumption and phase separation can lead to condensation at a nonequilibrium steady state, resulting in phase behaviors that are not described by equilibrium thermodynamics. Theoretical models of such chemically driven fluids typically invoke near-equilibrium approximations at small length scales. However, because dissipation occurs due to both molecular-scale chemical reactions and mesoscale diffusive transport, it has remained unclear which properties of phase...
-
作者:Gozashti, Landen; Nakamoto, Anne; Russell, Shelbi; Corbett-Detig, Russell
-
作者:Mildenberger, Matto; Constantino, Sara M.; Mahdavi, Paasha; Bergquist, Parrish; De Roche, Gabriel; Franzblau, Emma; Martinez-Alvarez, Cesar; Sturm, Ingmar
作者单位:University of California System; University of California Santa Barbara; Stanford University; University of Pennsylvania; University of California System; University of California San Diego; University of California System; University of California Los Angeles
摘要:Climate change caused by carbon pollution from the world's largest economies poses an existential threat to small-island states and territories this century. These places bear virtually no responsibility for climate change but will face sea-level rise, fresh water resource degradation, and intensified storms that will kill or dislocate exposed publics, and damage local economies. To alleviate this crisis, the global community has begun discussing who is responsible for climate mitigation and a...
-
作者:Richardson, James A.; Engelstadter, Jan; Letten, Andrew D.