-
作者：Nobakht, Jahangir; Pscherer, Andre; Renger, Jan; Goetzinger, Stephan; Sandoghdar, Vahid
作者单位：Max Planck Society; University of Erlangen Nuremberg; University of Erlangen Nuremberg
摘要：Atoms and molecules usually hybridize and form bonds when they come in very close proximity of each other. In this work, we show that molecules can hybridize even through far-field electromagnetic interactions mediated by the shared mode of an optical microcavity. We discuss a collective enhancement of the vacuum Rabi splitting and study super-and subradiant states that arise from the cavity-mediated coupling both in the resonant and dispersive regimes. Moreover, we demonstrate a two-photon tr...
-
作者：Pupulewatte, Heshani; Gorbunov, Maxim Y.; Moore, C. Mark; Selden, Corday R.; Keogh, Thomas J.; Furby, Joe; Hawley, Ruth; Lohan, Maeve C.; Bibby, Thomas S.; Falkowski, Paul G.
作者单位：Rutgers University System; Rutgers University New Brunswick; Rutgers University System; Rutgers University New Brunswick; NERC National Oceanography Centre; University of Southampton; Council for Scientific & Industrial Research (CSIR) - South Africa
摘要：Oxygenic photosynthesis requires excitation energy transfer from light- harvesting complexes (LHCs) to reaction centers (RCs) to drive photochemical redox chemistry. The effective absorption cross section of RCs dynamically responds to the light environment on time scales of seconds to days, allowing rapid acclimations to changes in spectral irradiance and photoprotection under high light, thereby optimizing light absorption for photochemistry. Although energy coupling between LHC-RCs has been...
-
作者：Sgarlata, Gabriele Maria; Maie, Tiago; de Zoeten, Tiago; Salmona, Jordi; Rasteiro, Rita; Chikhi, Lounes
作者单位：Instituto Gulbenkian de Ciencia; University of California System; University of California Davis; University of California System; University of California Davis; RWTH Aachen University; RWTH Aachen University Hospital; Universite Federale Toulouse Midi-Pyrenees (ComUE); Universite de Toulouse; Institut National Polytechnique de Toulouse; Centre National de la Recherche Scientifique (CNRS); Universite Toulouse III - Paul Sabatier; University of Bristol; Universidade de Lisboa
摘要：Natural habitats have undergone drastic changes in quality, continuity, and extent during the Pleistocene, influencing the distribution of many species. More recently, human activities have converted continuous habitats into fragmented and isolated patches. Recent meta-analyses suggest that habitat loss and fragmentation (HL&F) have negatively impacted the genetic diversity of species but very few studies have analyzed the consequences of HL&F on the spatial distribution of genetic diversity a...
-
作者：Chau, Ho Yin; Miller, Kenneth D.; Palmigiano, Agostina
作者单位：Columbia University; Columbia University; Columbia University; Columbia University; University of London; University College London
摘要：What are the principles that govern the responses of cortical networks to their inputs and the emergence of these responses from recurrent connectivity? Recent experiments have probed these questions by measuring cortical responses to two-photon optogenetic perturbations of single cells in the mouse primary visual cortex. A robust theoretical framework is needed to determine the implications of these responses for cortical recurrence. Here, we propose a formulation of the dependence of cell-ty...
-
作者：Park, Seung Kuk; Guo, Mo; Stamos, Jennifer L.; Kim, Wantae; Lee, Sidae; Zhang, Y. Jessie; Lambowitz, Alan M.
作者单位：Stanford Cancer Institute; Stanford University; University of Texas System; University of Texas Austin; University of Texas System; University of Texas Austin
摘要：A previous study found that a bacterial group II intron-like reverse transcriptase (G2L4 RT) evolved to function in double-strand break repair (DSBR) via microhomology-mediated end-joining (MMEJ) and that a mobile group II intron-encoded RT has a basal DSBR activity that uses conserved structural features of non-long terminal repeat (non-LTR)-retroelement RTs. Here, we determined G2L4 RT apoenzyme and snap-back DNA synthesis structures revealing unique structural adaptations that optimized its...
-
作者：Chen, Xuemin; Yao, Liangrui; Li, Wenwen; Ma, Shanshan; Yuan, Xingyun; Yang, Yang; Yuan, Yuan; Liu, Yumei; Liu, Lan; Wang, Huaibin; Gellert, Martin; Yang, Wei
作者单位：Anhui University; National Institutes of Health (NIH) - USA; NIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK)
摘要：The recombination activating genes 1 and 2 (RAG1/2) recombinase, which initiates V(D)J recombination in jawed vertebrates, evolved from RNaseH-like transposases such as Transib and ProtoRAG. However, its postcleavage transposase activity is strictly suppressed. Previous structural studies have focused only on the conserved core domains of RAG1/2, leaving the regulatory mechanisms of the noncore regions unclear. To investigate how RAG1/2 suppresses transposition and regulates DNA cleavage, we d...
-
作者：Yang, Siyan; Ji, Bingqiang; Feng, Yawei; Jin, Yuankai; Xu, Wanghuai; Lu, Jingyi; Qin, Xuezhi; Zhang, Huanhuan; Li, Mingyu; Xu, Zhenyu; Liu, Xiaonan; Xu, Luqing; Wang, Dehui; Wen, Rongfu; Wang, Zhenying; Wang, Steven; Ma, Xuehu; Wang, Zuankai
-
作者：Dubilier, Nicole
作者单位：Max Planck Society
-
作者：Lafuma, Fabien; Renvoise, Elodie; Clavel, Julien; Corfe, Ian J.; Escarguel, Gilles
作者单位：University of Helsinki; Universite PSL; Ecole Normale Superieure (ENS); Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); Institut National de la Sante et de la Recherche Medicale (Inserm); Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Ecology & Environment (INEE); Universite Claude Bernard Lyon 1; Geological Survey of Finland (GTK)
摘要：Morphological change occurs over macroevolutionary timescales under the action of natural selection and genetic drift combined with developmental processes shaping organogenesis. Although determining their relative weight is made difficult by discrepancies between paleontological and neontological data, mammalian tooth morphology may bridge the gap between fossil record and laboratory observations. Fossils indicate that mammals have frequently diversified after evolving molars bearing more cus...
-
作者：van der Heijden, Eva S. M.; Nasvall, Karin; Seixas, Fernando A.; Nobre, Carlos Eduardo Beserra; Maia, Artur Campos D.; Salazar-Carrion, Patricio; Walker, Jonah M.; Szczerbowski, Daiane; Schulz, Stefan; Warren, Ian A.; Cordova, Kimberly Gabriela Gavilanes; Sanchez-Carvajal, Maria Jose; Chandi, Franz; Arias-Cruz, Alex P.; Rueda-M, Nicol; Salazar, Camilo; Dasmahapatra, Kanchon K.; Montgomery, Stephen H.; McClure, Melanie; Absolon, Dominic E.; Mathers, Thomas C.; Santos, Camilla A.; McCarthy, Shane; Wood, Jonathan M. D.; Lamas, Gerardo; Bacquet, Caroline; Freitas, Andre Victor Lucci; Willmott, Keith R.; Iggins, Chris D. J.; Elias, Marianne; Meier, Joana I.
作者单位：Wellcome Trust Sanger Institute; University of Cambridge; Harvard University; Universidade Federal de Pernambuco; Universidade Federal de Pernambuco; Braunschweig University of Technology; Universidad del Rosario; University of York - UK; University of Bristol; Ifremer; Centre National de la Recherche Scientifique (CNRS); Universidad Nacional Mayor de San Marcos; Smithsonian Institution; Smithsonian Tropical Research Institute; Universidade Estadual de Campinas; State University System of Florida; University of Florida; Sorbonne Universite; Universite PSL; Ecole Pratique des Hautes Etudes (EPHE); Museum National d'Histoire Naturelle (MNHN); Centre National de la Recherche Scientifique (CNRS); Centre National de la Recherche Scientifique (CNRS); Institut National de la Sante et de la Recherche Medicale (Inserm); Universite PSL; College de France
摘要：A central question in evolutionary biology is what drives the diversification of lineages. Rapid, recent radiations are ideal systems for this question because they still show key morphological and ecological adaptations associated with speciation. While most research on recent radiations focuses on those occurring in insular environments, less attention has been given to continental radiations with complex species interactions. Here, we study the drivers of continental radiations of Melinaea ...
