31期

最新文章

• Cryo-EM structure and polar assembly of the PS2 S-layer of Corynebacterium glutamicum AI翻译
  作者：Sogues, Adria; Sleutel, Mike; Petit, Julienne; Megrian, Daniela; Bayan, Nicolas; Wehenkel, Anne Marie; Remaut, Han
  作者单位：Flanders Institute for Biotechnology (VIB); Vrije Universiteit Brussel; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); Pasteur Network; Universite Paris Cite; Institut Pasteur Paris; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); Pasteur Network; Universite Paris Cite; Institut Pasteur Paris; Pasteur Network; Institut Pasteur de Montevideo; Universite Paris Saclay; Centre National de la Recherche Scientifique (CNRS); CEA
  摘要：The polar-growing Corynebactertales have a complex cell envelope architecture charac-terized by the presence of a specialized outer membrane composed of mycolic acids. In some Corynebacteriales, this mytomembrane is further supported by proteinaceous surface layer or S-layer, whost function, structure, and mode of assembly remain largely enigmatic. Here, we isolated ex vivo PS2 S-layers from the industrially impor-tant Corynebacterium glutamicuu and determined its atomic structure by 3D cryo-E...
• Translocations contribute to population rescue in an imperiled woodpecker AI翻译
  作者：Lewanski, Alexander L.; Linderoth, Tyler; Thompson, Greg; Tringali, Angela; Angell, Emily; Bowman, Reed; Fitzpatrick, Sarah W.
  作者单位：Michigan State University; Michigan State University; Michigan State University
  摘要：Anthropogenic destruction and fragmentation of habitat restrict many species to small, isolated populations, which often experience high extirpation risk. Restoring connectivity through translocations is one approach for mitigating the demographic and genetic perils faced by small populations. However, translocation interventions often lack substantial postrelease monitoring, and thus important information including the performance of translocated individuals, the long- term impacts on the rec...
• Suturing fragmented landscapes: Mosaic hybrid zones in plants may facilitate ecosystem resiliency AI翻译
  作者：Massatti, Rob; Faske, Trevor M.; Barnes, Ivana M.; Leger, Elizabeth A.; Parchman, Thomas L.; Richardson, Bryce A.; Knowles, L. Lacey
  作者单位：United States Department of the Interior; United States Geological Survey; University of Michigan System; University of Michigan; Nevada System of Higher Education (NSHE); University of Nevada Reno; United States Department of Agriculture (USDA); United States Forest Service
  摘要：Many widespread plant taxa of western North America have diversified into phenotypically and genetically divergent lineages due to complex biogeographic histories across heterogeneous landscapes. Mosaic hybrid zones can form when geographically co-occurring, yet environmentally distinct, lineages cross-pollinate and form hybrids that occupy unique environmental niches absent of a geographic cline. This expands the total environmental space across which parental and hybrid individuals grow, res...
• From science to impact: Conserving ecological connectivity in large conservation landscapes AI翻译
  作者：Naidoo, Robin; Aylward, Cody; Elliott, Wendy; Keeley, Annika; Kinnaird, Margaret; Knight, Michael; Papp, Cristian- Remus; Thapa, Kanchan; Antelo, Rafael
  作者单位：World Wildlife Fund; University of British Columbia; Nelson Mandela University; Babes Bolyai University from Cluj
  摘要：Implementing ecological connectivity conservation in large landscapes requires cutting- edge science combined with consideration of ecological, socioeconomic, and cultural factors that collectively shape the outcomes of conservation efforts. We outline a theory of change (ToC) for connectivity conservation to improve the ecological condition of landscapes and biodiversity and the ecosystem services upon which humans depend. We review connectivity conservation efforts on four continents in larg...
• QnAs with Blake C. Meyers AI翻译
  作者：Ravindran, Sandeep; Meyers, Blake C.
• Indigenous territories and protected areas are crucial for ecosystem connectivity in the Amazon basin AI翻译
  作者：Ritter, Camila Duarte; Munoz, Jesus; Machado, Arielli Fabricio; Albert, James S.; Ribas, Camila C.; Carnaval, Ana C.; Ulloa, Carmen Ulloa; Carrillo, Juan D.; Tuomisto, Hanna; Armenteras, Dolors; Guayasamin, Juan M.
  作者单位：Institute Nacional de Pesquisas da Amazonia; Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Real Jardin Botanico de Madrid; Universidade Federal do Pampa; Harvard University; University of Louisiana Lafayette; City University of New York (CUNY) System; City University of New York (CUNY) System; Missouri Botanical Gardens; University of Fribourg; Swiss Institute of Bioinformatics; University of Turku; Aarhus University; Universidad Nacional de Colombia; Universidad San Francisco de Quito
  摘要：Ecosystem connectivity-the uninterrupted flow of natural processes within and among ecosystems-is critical for maintaining healthy ecosystem functions. However, in the Amazon drainage basin, multiple anthropogenic activities are rapidly disrupting connectivity. To assess the severity of this problem, we analyzed the spatial distributions of six major anthropogenic activities: dam construction, deforestation, fire, mining, oil and gas exploitation, and roads. We examined their impacts across fo...
• Mycobacteriophage-mediated gene transfer enables in vitro drug screening and in vivo tracking of Mycobacterium leprae (vol 122,e2508271122,2025) AI翻译
  作者：Das, Lahari; Chen, Bing; Rajagopalan, Saranathan; Vilcheze, Catherine; Mullholland, Claire V.; Berney, Michael; Andrews, Patrick K.; Edwards, Ashley; Lahiri, Ramanuj; Jacobs Jr, William R.
• Prg4+ fibroadipogenic progenitors in muscle are crucial for bone fracture repair AI翻译
  作者：He, Qi; Lu, Jiawei; Liang, Qiushi; Yao, Lutian; Sun, Tingfang; Wang, Huan; Duffy, Michael; Jiang, Xi; Lin, Yuewei; Lee, Ji- Hyung; Ahn, Jaimo; Dyment, Nathaniel A.; Mourkioti, Foteini; Boerckel, Joel D.; Qin, Ling
  作者单位：University of Pennsylvania; Guangzhou University of Chinese Medicine; Tongji University; Emory University; University of Pennsylvania; University of Pennsylvania
  摘要：Clinically, compromised fracture healing often occurs at sites with less muscle coverage and muscle flaps can provide the necessary healing environment for appropriate healing in severe bone loss. However, the underlying mechanisms are largely unknown. Here, we established a mouse reporter model for studying muscle cell contribution to bone fracture repair. Analyzing skeletal muscle scRNA-seq datasets revealed that Prg4 marks a fibroadipogenic progenitor (FAP) subpopulation. In mice, Prg4+ cel...
• AI-AI bias: Large language models favor communications generated by large language models AI翻译
  作者：Laurito, Walter; Davis, Benjamin; Grietzer, Peli; Gavenciak, Tomas; Bohm, Ada; Kulveit, Jan
  作者单位：Charles University Prague
  摘要：Are large language models (LLMs) biased in favor of communications produced by LLMs, leading to possible antihuman discrimination? Using a classical experimental design inspired by employment discrimination studies, we tested widely used LLMs, including GPT-3.5, GPT-4 and a selection of recent open-weight models in binary choice scenarios. These involved LLM-based assistants selecting between goods (the goods we study include consumer products, academic papers, and film-viewings) described eit...
• Genomic origins and evolution of neo- sex chromosomes in Pacific Island birds AI翻译
  作者：Muirhead, Christina A.; Marti, Emiliano; Shogren, Elsie H.; Uy, J. Albert C.; Presgraves, Daven C.
  作者单位：University of Rochester
  摘要：The standard model of sex chromosome evolution is based on ancient XY or ZW systems. Young neo-sex chromosomes that form via the translocation of autosomal material to preexisting sex chromosomes provide materials to study early events in sex chromosome evolution. Neo-sex chromosomes are taxonomically widespread but, until recently, appeared to be rare in female-heterogametic taxa, including birds. Here, we report on the comparative evolutionary genomics of newly discovered neo-Z and neo-W sex...