33期

最新文章

• Supporting Information for Rei et al., Basolateral amygdala bidirectionally modulates stress-induced hippocampal learning and memory deficits through a p25/Cdk5-dependent pathway ( vol 112 , pg 7291-7296 , 2015 ) AI翻译
  作者：Rei, Damien; Mason, Xenos; Seo, Jinsoo; Rudenko, Andrii; Wang, Jun; Rueda, Richard; Siegert, Sandra; Cho, Sukhee; Canter, Rebecca G.; Mungenast, Alison E.; Deisseroth, Karl; Tsai, Li - Huei
• Increased microbial carbon use efficiency upon abrupt permafrost thaw AI翻译
  作者：Qin, Shuqi; Wang, Guanqin; Zhang, Dianye; Yang, Yuanhe
  作者单位：Chinese Academy of Sciences; Nanjing Institute of Geology & Paleontology, CAS; Institute of Botany, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS
  摘要：Soil carbon (C) dynamics upon permafrost thaw represents a major uncertainty in climate projections. Both soil C loss and formation in permafrost regions are mediated by microorganisms, and the balance of these two processes could be characterized by a synthetic metric termed microbial carbon use efficiency (CUE, defined as the ratio of C used for growth over C uptake). However, how microbial CUE responds to permafrost thaw remains unclear due to the lack of direct experimental evidence. Here,...
• Trends in coastal storm impacts are not only about changes in hurricanes AI翻译
  作者：Broccoli, Anthony J.
  作者单位：Rutgers University System; Rutgers University New Brunswick
• Evolutionarily divergent nidovirus with an exceptionally large genome identified in Pacific oysters undergoing mass mortality AI翻译
  作者：Zhong, Kevin Xu; Chan, Amy M.; Miller, Kristina M.; Saunders, Rob; Suttle, Curtis A.
  作者单位：University of British Columbia; Fisheries & Oceans Canada; University of British Columbia; University of British Columbia; University of British Columbia
  摘要：Metatranscriptomic data from a mass-mortality event of adult Pacific Oysters, Crassostrea (Magallana) gigas, the most widely cultivated shellfish globally, revealed a nidovirus shown to replicate in a bivalve, Pacific Oyster Nidovirus 1 (PONV1). At 64,331 bp of linear bisegmented, positive-sense single-stranded RNA, PONV1 has one of the largest genomes reported for an RNA virus. Moreover, transcriptomic data reveal that many conspecific viruses of PONV1 occur in Pacific oysters from Europe and...
• Geographical diversity of peer reviewers shapes author success AI翻译
  作者：Dumlao, James M. Zumel; Teplitskiy, Misha
  作者单位：University of Michigan System; University of Michigan
  摘要：Scientific institutions like funding agencies and journals rely on peer reviewers to select among competing submissions. How does the geographical diversity of reviewers affect which authors are selected? If reviewers typically favor submissions from their own countries, but reviewers from only some countries are well represented in the reviewer pool, this can create a geographical representation bias favoring authors from those well-represented countries. Using administrative data on 204,718 ...
• Tumor-promoting UBR4 coordinates impaired mitophagy-associated senescence and lung adenocarcinoma pathogenesis (vol 122 , e2425015122, 2025) AI翻译
  作者：Jeong, Dawon; Park, Seo Hyeong; Kim, Jiwon; Kim, Hyeyoon; Jang, Yejin; Koh, Jaemoon; Jeon, Yoon Kyung; Tasaki, Takafumi; Kwon, Yong Tae; Han, Dohyun; Cho, Sung-Yup; Lee, Min Jae
• Gene regulatory logic of the interferon-β enhancer is characterized by two selectively deployed modes of transcription factor synergy AI翻译
  作者：Schiffman, Allison; Cheng, Zhang; Ourthiague, Diana; Hoffmann, Alexander
  作者单位：University of California System; University of California Los Angeles; University of California System; University of California Los Angeles
  摘要：Type I interferon IFN beta is a key immune response cytokine, and when its expression is dysregulated, it causes disease. The regulation of IFN beta enhancer has been a touchpoint of mammalian gene control research since the discovery of functional synergy between two stimulus-responsive transcription factors (TFs), nuclear factor kappa B (NF kappa B) and interferon regulatory factors (IRF). However, subsequent gene knockout studies revealed that in some conditions either NF kappa B or IRF act...
• A proteomic signature of healthspan ( vol 122 , e2414086122, 2025) AI翻译
  作者：Kuo, Chia-Ling; Liu, Peiran; Drouard, Gabin; Vuoksimaa, Eero; Kaprio, Jaakko; Ollikainen, Miina; Chen, Zhiduo; Pilling, Luke C.; Atkins, Janice L.; Fortinsky, Richard H.; Kuchel, George A.; Diniz, Breno S.
  作者单位：University of Connecticut; University of Connecticut; University of Helsinki; University of Exeter; University of Connecticut
• Analytical solutions for light propagation of LED AI翻译
  作者：Zhang, Haohui; Zhang, Kaiqing; Wu, Mingzheng; Li, Shupeng; Bodkin, Kevin L.; Kozorovitskiy, Yevgenia; Rogers, John A.; Huang, Yonggang
  作者单位：Northwestern University; Dalian University of Technology; Northwestern University; Northwestern University; Northwestern University; Northwestern University; Northwestern University; Northwestern University; Feinberg School of Medicine
  摘要：Analytical solutions of diffusion theory for light propagation in turbid media are essential for optical diagnostics and therapeutic applications, including cerebral oximetry, hemodynamic monitoring, and photostimulation. While existing solutions work reasonably well for collimated light sources-lasers and optical fibers-analytical solutions for LEDs remain missing, despite the growing use of LEDs in wearable and implantable bioelectronics. We present a method to solve the diffusion theory and...
• Maintenance suppression enhances subsequent associative learning AI翻译
  作者：Zhang, Ziyao; Lewis-Peacock, Jarrod A.
  作者单位：University of Texas System; University of Texas Austin
  摘要：Removing irrelevant information from working memory (WM) can free cognitive resources and reduce interference with current task goals. Beyond these immediate benefits, removal may also support long-term memory processes. We tested this hypothesis using an associative memory paradigm with directed forgetting instructions and characterized the underlying neural mechanisms. In complementary behavioral (N = 22) and fMRI (N = 17) experiments, participants completed an ABC associative memory task us...