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作者:von der Heyde, Benjamin; Srinivasan, Anand; Birwa, Sumit Kumar; von der Heyde, Eva Laura; Hoehn, Steph S. M. H.; Coldstein, Raymond E.; Hallmann, Armin
作者单位:University of Bielefeld; University of Cambridge
摘要:The evolution of multicellularity involved the transformation of a simple cell wall of unicellular ancestors into a complex, multifunctional extracellular matrix (ECM). A suitable model organism to study the formation and expansion of an ECM during ontogenesis is the multicellular green alga Volvox carteri, which, along with the related volvocine algae, produces a complex, self-organized ECM composed of multiple substructures. These self-assembled structures primarily consist of hydroxyproline...
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作者:Papikian, Ashot; Rattner, Rachel J.; Kao, Jenni; Hauser, Neil; Allsing, Nicholas; Mamerto, Allen; Hartwick, Nolan T.; Colt, Kelly; Michael, Todd P.
作者单位:Salk Institute; University of California System; University of California San Diego; University of California System; University of California San Diego
摘要:Plant genomes have undergone multiple rounds of whole-genome duplication (WGD) throughout their evolutionary history. As a result, many species, including Arabidopsis thaliana, retain duplicated genomic segments, or syntenic regions, which harbor large numbers of paralogous genes preserved from these ancient WGD events. We deleted four large, duplicated blocks, ranging from similar to 115 kb to similar to 684 kb using Staphylococcus aureus Cas9 to explore the effects of knocking out these bloc...
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作者:Jaishankar, Jananee; Yang, Hyojik; O'Keefe, Ian P.; Tenaglia, Brandon M.; Kinch, Lisa N.; Ernst, Robert K.; Orth, Kim
作者单位:University of Texas System; University of Texas Southwestern Medical Center; Howard Hughes Medical Institute; University System of Maryland; University of Maryland Baltimore; University System of Maryland; University of Maryland Baltimore; University of Texas System; University of Texas Southwestern Medical Center
摘要:Vibrio parahaemolyticus (V. para), a Gram-negative halophilic bacterium, is the leading cause of seafood-borne gastroenteritis. While the cytotoxic and enterotoxic capabilities of this bacterium have been previously investigated, the strategies it employs to circumvent innate immune detection by the host remain poorly understood. Bacterial lipopolysaccharide (LPS) serves as the major pathogen-associated molecular pattern that triggers host inflammatory responses, and its lipid A structure cont...
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作者:Xie, Yuyang; Shen, Zehao; Camarero, J. Julio; Penuelas, Josep; Wang, Xuejing; Li, Jitang; Rao, Wenge; Chen, Xiangwu; Zhao, Fu; Feng, Xiao
作者单位:Peking University; Peking University; University of North Carolina; University of North Carolina Chapel Hill; University of North Carolina School of Medicine; Yunnan University; Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Instituto Pirenaico de Ecologia (IPE); Centro de Investigacion Ecologica y Aplicaciones Forestales (CREAF-CERCA); Autonomous University of Barcelona; Centro de Investigacion Ecologica y Aplicaciones Forestales (CREAF-CERCA)
摘要:Alpine treeline is a prominent biogeographic feature worldwide, determined by the physiological limit of tree life form. There are considerable variations in the various dimensions of physiological limit among tree taxa; thus, varied environmental drivers and spatial patterns are expected for different tree taxa at treelines. However, such taxonomic variability of treeline is often overlooked in large-scale studies. Here, we assembled, to our knowledge, the most comprehensive dataset of tree s...
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作者:Zhang, Zhuquan; Ning, Honglie; Liu, Zi-Jie; Hou, Jin; Mohite, Aditya D.; Baldini, Edoardo; Gedik, Nuh; Nelson, Keith A.
作者单位:Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); Rice University; Rice University; University of Texas System; University of Texas Austin
摘要:In 1964, Keldysh laid the groundwork for strong-field physics in atomic, molecular, and solid-state systems by delineating a ubiquitous transition from multiphoton absorption to classical field-driven electron tunneling under intense electromagnetic waves. While both processes in semiconductors can generate carriers and result photon emission through electron-hole recombination, the low quantum yields most materials have hindered direct observation of the Keldysh crossover. Leveraging the larg...
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作者:Jaijyan, Dabbu Kumar; Selariu, Anca; Cosme, Ruth Cruz -; Tong, Mingming; Yang, Shaomin; Stefa, Alketa; Kekich, David; Sadoshima, Junichi; Herbig, Utz; Tang, Qiyi; Church, George; Parrish, Elizabeth L.; Zhu, Hua
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作者:Lehmann, Johannes; Barrios, Edmundo; Devault, Mariana; Li, Lucinda; Nelson, Rebecca; Six, Johan; Trimmer, John
作者单位:Cornell University; Cornell University; Cornell University; Food & Agriculture Organization of the United Nations (FAO); Cornell University; Swiss Federal Institutes of Technology Domain; ETH Zurich; Syracuse University
摘要:The circular bionutrient economy is defined here as the circular economy of nutrients in managed organic residues. Here, we posit that biochar technology can stimulate the circular bionutrient economy by meeting the following three requirements: 1) nutrients are captured in a dry form, increasing market value and lowering transportation cost; 2) individual nutrients can be captured separately and combined as needed for particular plants and soils; 3) all pathogens and most pollutants can be re...
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作者:Obradovich, Nick; Lawrance, Emma L.; Minor, Kelton
作者单位:Laureate Institute for Brain Research, Inc.; Massachusetts Institute of Technology (MIT); University of Tulsa; Imperial College London; Imperial College London; Columbia University; University of Copenhagen