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作者:Hendrick, Martin; Rinaldo, Andrea; Manoli, Gabriele
作者单位:Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Centro Euro-Mediterraneo sui Cambiamenti Climatici (CMCC)
摘要:A current tenet in the science of cities is the emergence of power-law relations between population size and a variety of urban indicators, echoing allometric scaling in living organisms akin to Kleiber's law. However fascinating, existing scaling theories suffer from biases related to the ad-hoc definition of city boundaries and to their neglect of intraurban variability of city properties. Here, to deal rigorously with biases, we explore the hypothesis that the empirical statistics of intrac...
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作者:Bassiouni, Maoya; Smith, Nicholas G.; Reu, Jacqueline C.; Penuelas, Josep; Keenan, Trevor F.
作者单位:University of California System; University of California Berkeley; Texas Tech University System; Texas Tech University; Autonomous University of Barcelona; Consejo Superior de Investigaciones Cientificas (CSIC); Centro de Investigacion Ecologica y Aplicaciones Forestales (CREAF-CERCA); Centro de Investigacion Ecologica y Aplicaciones Forestales (CREAF-CERCA); United States Department of Energy (DOE); Lawrence Berkeley National Laboratory
摘要:Widespread evidence of decreasing leaf nutrients has raised concerns about ecosystem productivity under global change. Interpreting trends in leaf nutrients has important implications for the fate of ecosystem services, particularly the role of forests in mitigating climate change and sustaining quality food sources. Here, we challenge the common interpretation that decreasing leaf nitrogen concentration (LNC) is evidence of increasing nutrient limitations on ecosystem primary productivity.Ins...
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作者:Georgiou, Dimitrios; Sun, Danqi; Liu, Xing; Athanasiou, Christos E.
作者单位:University System of Georgia; Georgia Institute of Technology; New Jersey Institute of Technology
摘要:Over 350 million metric tons of plastic waste are generated annually, with most ending up in landfills, dumps, or the environment, posing significant risks. Mechanical recycling remains underutilized, largely due to the high variability in the mechanical properties of recycled plastics (recyclates). This variability undermines performance reliability and hinders the adoption of recyclates in demanding industrial applications. Inspired by natural materials, known for their mechanical robustness...
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作者:Pederson, Thoru
作者单位:University of Massachusetts System; UMass Chan Medical School; University of Massachusetts Worcester
摘要:Having trained as a physician, & Eacute;tienne-& Eacute;mile Baulieu soon turned his focus to research, as early as his medical internship. He went on to make major contributions on ketosteroids and other steroids, such as estrogen, and how they act on target organs through receptors to which the hormones bind and activate physiological responses. Later, he consulted with a French pharmaceutical company, encouraging them to pursue his concept for an antigestational agent, which became the icon...
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作者:Zhao, Zihe; Li, Ao; Zhu, Yan; Cen, Shaoqin; Liu, Qing; Zhang, Yuan; Fan, Hanqi; Hou, Zhenxing; Ma, Dengbin; Liu, Dingding; Duan, Maoli; Qian, Xiaoyun; Chai, Renjie; Wan, Guoqiang; Gao, Xia
作者单位:Nanjing University; Nanjing University; Nanjing Medical University; Nanjing University; Nanjing University; Nanjing University; Karolinska Institutet; Karolinska University Hospital; Karolinska Institutet; Southeast University - China
摘要:Hearing loss (HL) in patients with systemic lupus erythematosus (SLE) has been widely reported, though the underlying mechanisms remain unclear. In this study, we demonstrate significant HL in an imiquimod-induced mouse model of SLE, accompanied by CD8+ T lymphocytes and natural killer cells mediate BLB disruption, with granzyme b (Gzmb) acting as the primary factor inducing cell death of the cochlear capillary endotheof hearing thresholds in imiquimod-induced SLE model mice, suggesting a ther...
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作者:Agrawal, Rachana; Seager, Sara; Iakubivskyi, Iaroslav; Buchanan, Weston P.; Glidden, Ana; Seager, Maxwell D.; Bains, William; Huang, Jingcheng; Petkowski, Janusz J.
作者单位:Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); University of Tartu; Tartu Observatory; Cardiff University; Wroclaw University of Science & Technology
摘要:The discovery of thousands of exoplanets and the emergence of telescopes capable of exoplanet atmospheric characterization have intensified the search for habitable worlds. Due to selection biases, many exoplanets under study are planets deemed inhospitable because their surfaces are too warm to support liquid water. We propose that such planets could still support life through ionic liquids: Liquid salts with negligible vapor pressure that can persist on warm planets with thin atmospheres, wh...
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作者:Cai, Xun; Han, Zhaoyu; Li, Zi-Xiang; Kivelson, Steven A.; Yao, Hong
作者单位:Chinese Academy of Sciences; Institute of Physics, CAS; Stanford University; Tsinghua University
摘要:A quantum spin liquid (QSL) is an exotic insulating phase with emergent gauge fields and fractionalized excitations. However, the unambiguous demonstration of the existence of a QSL in a nonengineered microscopic model (or in any material) remains challenging. Here, using numerically exact sign-problem-free quantum Monte Carlo simulations, we show that a QSL arises in a nonengineered electron-phonon model. Specifically, we investigate the ground-state phase diagram of the bond Su-Schrieffer-He...
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作者:Constant-Varlet, Charlotte; Nakai, Tomoya; Longo, Lea; Bouchet, Honorine; Prado, Jerome
作者单位:Institut National de la Sante et de la Recherche Medicale (Inserm); Universite Jean Monnet; Universite Lyon 1; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); Universite Paris Cite; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute for Humanities & Social Sciences (INSHS)
摘要:Parental skills are among the most powerful predictors of children's outcomes. While distal genetic and environmental pathways likely contribute to skill transmission within families, much less is known about the proximal neural markers that support the transmission of cognitive functioning from parents to children. It is also unclear whether brain similarity between parents and children predicts similarity in cognitive skills. In this study, we used fMRI to measure brain activity associated w...
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作者:Brumfield, Kyle D.; Usmani, Moiz; Long, Daniel M.; Lupari, Henry A.; Pope, Robert K.; Jutla, Antarpreet S.; Huq, Anwar; Colwell, Rita R.
作者单位:University System of Maryland; University of Maryland College Park; University System of Maryland; University of Maryland College Park; University of Alabama System; University of Alabama Birmingham; National Biodefense Analysis & Countermeasures Center; State University System of Florida; University of Florida; University System of Maryland; University of Maryland College Park
摘要:Climate change significantly impacts the incidence and abundance of microorganisms, including those essential for environmental cycles and those pathogenic to humans and animals. Shifts in conditions favorable for microbial growth have expanded the geographic range of many pathogens, contributing to the emergence and reemergence of infectious diseases. Waterborne diseases pose severe risks in regions where adverse climate conditions intersect with population vulnerabilities, especially inadequ...
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作者:Nelson, Rachel S.; Grossman, Margaret G.; Klug, Zasu M.; Calamari, Mia; Donayre, Alvaro; Cybulski, Thaddeus; Schooley, Jared; Griffith, Garett J.; Corcos, Daniel M.; Wright, Donald E.; Wallace, Jessica C.; Yang, Da Som; Wright Jr, John A.; Rogers, John A.; Lee, Stephen P.; Ghaffari, Roozbeh; Aranyosi, A. J.; Jain, Manu
作者单位:Northwestern University; Feinberg School of Medicine; Northwestern University; Northwestern University; Chung Ang University; Northwestern University; Northwestern University; Northwestern University; US Department of Veterans Affairs; Veterans Health Administration (VHA); Jesse Brown VA Medical Center; Northwestern University
摘要:Sweat parameters such as volume and chloride concentration may offer invaluable clinical insights for people with CF (PwCF). Pilocarpine-induced sweat collection for chloridometry measurement is the gold standard for a CF diagnosis, but this technique is cumbersome and not suitable for remote settings or repeat measurements. We have previously reported the utility of a skin-interfaced microfluidic device (CF Patch) in conjunction with a smartphone image processing platform that enables real-ti...