35期

最新文章

• Unveiling street art: A multimodal and multitechnique approach for analyzing and mapping painting materials on large murals AI翻译
  作者：Sabatinia, Francesca; Albertina, Fauzia; Dohertya, Brenda; Monicoa, Letizia; Rosia, Francesca; Butic, David; Romania, Aldo; Peccia, Antonio; Abated, Nicodemo; Sileod, Maria; Amodiod, Antonio Minervino; Masinid, Nicola; Pizzimentie, Silvia; Deganoe, Ilaria; Modugnoe, Francesca; Campanellaf, Beatrice; Legnaiolif, Stefano; Cartechinia, Laura
  作者单位：University of Milano-Bicocca; University of Basilicata; University of Naples Federico II; University of Perugia; University of Perugia; University of Pisa; Consiglio Nazionale delle Ricerche (CNR); Isituto di Chimica dei Composti Organometallici (ICCOM-CNR)
  摘要：Street art murals are increasingly recognized as valuable contemporary artworks, often attaining significant artistic, historical, and social importance. As these murals become integral parts of cultural heritage, finding efficient strategies for their conservation is crucial. However, their typical large surface areas, heterogeneous materials, and high variability in exposure to environmental and pollution factors pose significant challenges in establishing appropriate analytical strategies t...
• Nucleotide-and metalloid-driven conformational changes in the arsenite efflux ATPase ArsA AI翻译
  作者：Mahajan, Shivansh; Pall, Ashley E.; Li, Yancheng E.; Stemmler, Timothy L.; Rees, Douglas C.; Clemons Jr, William M.
  作者单位：California Institute of Technology; Wayne State University; Howard Hughes Medical Institute; Chan Zuckerberg Initiative (CZI); Medical University of South Carolina
  摘要：Arsenite (AsIII) is toxic to all organisms due to its ability to tightly bind exposed thiols within cells. An important AsIII resistance mechanism in prokaryotes involves proteins encoded by the ars operon. A central component of the ars operon in many bacteria is the cytoplasmic ATPase, ArsA, which orchestrates a series of nucleotide-dependent handoffs, starting with the capture of AsIII by the ArsD metallochaperone and culminating in its removal from the cell by the ArsB efflux pump. Althoug...
• Chants across seven traditions share acoustic traits that enhance subjective relaxation AI翻译
  作者：Canessa-Pollard, Valentina; Anikin, Andrey; Reby, David
  作者单位：University of Chichester; Lund University; Institut Universitaire de France
  摘要：For over 5,000 y, chanting has been practiced across many Western and Eastern traditions. However, there is hardly any empirical research on 1) whether chants from across the globe share common acoustic properties, 2) whether these acoustic features make them distinct from other human vocalizations, and 3) the extent to which they may positively impact listeners' well-being. Here, we collected 242 chants belonging to seven distinct traditions and associated with a wide range of language famili...
• Abiotic synthesis during the interaction of ferrous chloride-rich silicic fluids with marble under high-grade metamorphic conditions AI翻译
  作者：Fei, Chenhui; Guo, Shun; Li, Yibing; Liu, Jingbo
  作者单位：Chinese Academy of Sciences; Institute of Geology & Geophysics, CAS; Zhejiang Ocean University; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS
  摘要：Ferrous chloride-rich silicic fluid and melt infiltration led to the decarbonation of dolomitic marble in the Chinese Sulu ultrahigh-pressure metamorphic terrain under temperatures ranging from 670 to 800 degrees C, pressures from the aragonite + albite to calcite stability fields and the oxygen fugacities between the hematite-magnetite and pyrite-pyrrhotite-magnetite buffers, resulting in the formation of olivine marble and diopsidite. The inclusions in zircons trapped during the decarbonatio...
• Communication increases cooperation among students in a coordination game AI翻译
  作者：Hallers-Haalboom, Elizabeth T.; De Jaegher, Kris J. M.; Sterck, Elisabeth H. M.; Brosnan, Sarah F.; Vermande, Marjolijn M.
  作者单位：Tilburg University; Utrecht University; Utrecht University; University System of Georgia; Georgia State University; University System of Georgia; Georgia State University; Utrecht University
  摘要：Cooperation often requires individuals to balance personal risk with mutual gain. The Stag Hunt game provides a well- established paradigm for studying such decision- making. Prior research suggested that verbal communication about the game correlated with participants finding the optimal coordinated solution, but these studies either did not manipulate communication directly or informed participants of the payoff structure in advance. This study examined whether communication improves coopera...
• Cohort mortality forecasts indicate signs of deceleration in life expectancy gains AI翻译
  作者：Andrade, Jose; Camarda, Carlo Giovanni; Arolas, Hector Pifarre
  作者单位：Max Planck Society; University of Wisconsin System; University of Wisconsin Madison; University of Wisconsin System; University of Wisconsin Madison; University of Wisconsin System; University of Wisconsin Madison
  摘要：trend will continue or life expectancy gains will decelerate in the near future remains unclear. To answer this question, we apply multiple established and recently developed mortality forecasting methods to estimate cohort life expectancy for individuals born between 1939 and 2000 in 23 high-income countries. Across all forecasting methods, our results robustly and consistently indicate a deceleration in cohort life expectancy. The previously observed pace of improvement, 0.46 y per cohort, d...
• Shared metabolism between a bacterial and fungal species that reside in the human gut AI翻译
  作者：Gause, Haley; Johnson, Alexander D.
  作者单位：University of California System; University of California San Francisco; University of California System; University of California San Francisco
  摘要：The fungal species Candida albicans and the bacterium Enterococcus faecalis are members of the human gut microbiome. To explore the range of interactions between these two species, we utilized dual RNA- sequencing to transcriptionally profile both C. albicans and E. faecalis during coculture (compared with monoculture controls) under two conditions: 1) an in vitro setting that mimics certain features of the gut environment and 2) a gnotobiotic mouse gut model. RNA- seq analysis revealed a larg...
• Thermodynamics of calcium binding to heparin: Implications of solvation and water structuring for polysaccharide biofunctions AI翻译
  作者：Knight, Brenna M.; Gallagher, Connor M. B.; Schulz, Michael D.; Edgar, Kevin J.; McNaul, Caylyn D.; McCutchin, Christina A.; Dove, Patricia M.
  作者单位：Virginia Polytechnic Institute & State University; Virginia Polytechnic Institute & State University; Virginia Polytechnic Institute & State University; Virginia Polytechnic Institute & State University; Virginia Polytechnic Institute & State University; Virginia Polytechnic Institute & State University
  摘要：Heparan sulfates are found in all animal tissues and have essential roles in living systems. This family of biomacromolecules modulates binding to calcium ions (Ca2+) in low free energy reactions that influence biochemical processes from cell signaling and anticoagulant efficacy to biomineralization. Despite their ubiquity, the thermodynamic basis for how heparans and similarly functionalized biomolecules regulate Ca2+ interactions is not yet established. Using heparosan (Control) and heparins...
• Reconfigurable photothermal doping filament for selective spin manipulation and addressing AI翻译
  作者：Liu, Zhi-Wei; Ma, Meng-Qi; Sun, Bo-Wen; Li, Liang; Jiang, Wang; Zang, Han-Xiang; Bai, Zhe; Dong, Yang; Zhang, Shao-Chun; Chen, Xiang-Dong; Zou, Chong-Wen; Guo, Guang-Can; Sun, Fang-Wen
  作者单位：Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; CAS Center for Excellence in Quantum Information & Quantum Physics; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Hefei National Laboratory
  摘要：The room temperature manipulation of solid-state spins provides an opportunity to develop quantum applications under ambient conditions. Local electromagnetic fields, that usually produced by current in micro/nanoscale metal wires, have been employed for the coherent driving and addressing of spin qubit. However, the fixed distribution limits the spatial selectivity and efficiency of qubit manipulation, which is of central importance in a scaled-up quantum system. Here, we report a solution by...
• CRISPR with Transcriptional Readout reveals influenza transcription is modulated by NELF and can precipitate an interferon response AI翻译
  作者：Vicary, Alison C.; Jordan, Sydney N. Z.; Mendes, Marisa; Swaminath, Sharmada; Castro, Lennice K.; Porter, Justin S.; Vo, Kevin D.; Russell, Alistair B.
  作者单位：University of California System; University of California San Diego
  摘要：Transcription of interferons upon viral infection is critical for cell-intrinsic innate immunity. This process is influenced by many host and viral factors. To identify host factors that modulate interferon induction within cells infected by influenza A virus, we developed CRISPR with Transcriptional Readout using sequencing (CRITR-seq). CRITR-seq is a method linking CRISPR guide sequence to activity at a promoter of interest. Employing this method, we find that depletion of the Negative Elong...