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作者:Reardon, Sara
摘要:A system that edits RNA rather than DNA can give new life to exhausted CAR T cells.
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作者:Gewin, Virginia
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作者:Konkel, Miriam K.; Casanova, Emily L.
作者单位:Clemson University; Loyola University New Orleans
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作者:Ghafari, Mahan; Hall, Matthew; Golubchik, Tanya; Ayoubkhani, Daniel; House, Thomas; MacIntyre-Cockett, George; Fryer, Helen R.; Thomson, Laura; Nurtay, Anel; Kemp, Steven A.; Ferretti, Luca; Buck, David; Green, Angie; Trebes, Amy; Piazza, Paolo; Lonie, Lorne J.; Studley, Ruth; Rourke, Emma; Smith, Darren L.; Bashton, Matthew; Nelson, Andrew; Crown, Matthew; McCann, Clare; Young, Gregory R.; dos Santos, Rui Andre Nunes; Richards, Zack; Tariq, Mohammad Adnan; Cahuantzi, Roberto; Barrett, Jeff; Fraser, Christophe; Bonsall, David; Walker, Ann Sarah; Lythgoe, Katrina
作者单位:University of Oxford; University of Oxford; University of Oxford; University of Sydney; University of Leicester; University of Manchester; University of Oxford; Wellcome Centre for Human Genetics; Northumbria University; Northumbria University; Wellcome Trust Sanger Institute; Oxford University Hospitals NHS Foundation Trust; University of Oxford; University of Oxford; University of Oxford; University of Oxford; University of London; University College London; Medical Research Council Clinical Trials Unit
摘要:Persistent SARS-CoV-2 infections may act as viral reservoirs that could seed future outbreaks(1-5), give rise to highly divergent lineages(6-8) and contribute to cases with post-acute COVID-19 sequelae (long COVID)(9,10). However, the population prevalence of persistent infections, their viral load kinetics and evolutionary dynamics over the course of infections remain largely unknown. Here, using viral sequence data collected as part of a national infection survey, we identified 381 individua...
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作者:Dolgin, Elie
摘要:Imaging and molecular manipulation reveal how biomolecular condensates form and offer clues to the role of phase separation in health and disease.
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作者:Seo, Jaemin; Kim, Sangkyeun; Jalalvand, Azarakhsh; Conlin, Rory; Rothstein, Andrew; Abbate, Joseph; Erickson, Keith; Wai, Josiah; Shousha, Ricardo; Kolemen, Egemen
作者单位:Princeton University; Chung Ang University; Princeton University; United States Department of Energy (DOE); Princeton Plasma Physics Laboratory; Princeton University
摘要:For stable and efficient fusion energy production using a tokamak reactor, it is essential to maintain a high-pressure hydrogenic plasma without plasma disruption. Therefore, it is necessary to actively control the tokamak based on the observed plasma state, to manoeuvre high-pressure plasma while avoiding tearing instability, the leading cause of disruptions. This presents an obstacle-avoidance problem for which artificial intelligence based on reinforcement learning has recently shown remark...
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作者:Yang, Yu-Han; Troja, Eleonora; O'Connor, Brendan; Fryer, Chris L.; Im, Myungshin; Durbak, Joe; Paek, Gregory S. H.; Ricci, Roberto; Bom, Clecio R.; Gillanders, James H.; Castro-Tirado, Alberto J.; Peng, Zong-Kai; Dichiara, Simone; Ryan, Geoffrey; van Eerten, Hendrik; Dai, Zi-Gao; Chang, Seo-Won; Choi, Hyeonho; De, Kishalay; Hu, Youdong; Kilpatrick, Charles D.; Kutyrev, Alexander; Jeong, Mankeun; Lee, Chung-Uk; Makler, Martin; Navarete, Felipe; Perez-Garcia, Ignacio
作者单位:University of Rome Tor Vergata; Istituto Nazionale Astrofisica (INAF); George Washington University; University System of Maryland; University of Maryland College Park; National Aeronautics & Space Administration (NASA); NASA Goddard Space Flight Center; United States Department of Energy (DOE); Los Alamos National Laboratory; United States Department of Energy (DOE); Los Alamos National Laboratory; University of Arizona; University of New Mexico; George Washington University; Seoul National University (SNU); Istituto Nazionale di Ricerca Metrologica (INRIM); Istituto Nazionale Astrofisica (INAF); Centro Brasileiro de Pesquisas Fisicas; Centro Federal de Educacao Tecnologica Celso Suckow da Fonseca (CEFET-RJ); Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Instituto de Astrofisica de Andalucia (IAA); Consejo Superior de Investigaciones Cientificas (CSIC); Universidad de Malaga; Beijing Normal University; Beijing Normal University; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Perimeter Institute for Theoretical Physics; University of Bath; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Massachusetts Institute of Technology (MIT); Northwestern University; Northwestern University; Korea Astronomy & Space Science Institute (KASI); Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET)
摘要:Observationally, kilonovae are astrophysical transients powered by the radioactive decay of nuclei heavier than iron, thought to be synthesized in the merger of two compact objects1-4. Over the first few days, the kilonova evolution is dominated by a large number of radioactive isotopes contributing to the heating rate2,5. On timescales of weeks to months, its behaviour is predicted to differ depending on the ejecta composition and the merger remnant6-8. Previous work has shown that the kilono...
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作者:[Anonymous]
摘要:The engine of a microscopic motor can be coupled or uncoupled from the rotor by means of DNA coatings that respond to a variety of stimuli.
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作者:Coleman, Jude
摘要:The laboratory-grown food uses rice as a scaffold for cultured meat.
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作者:[Anonymous]
摘要:The animals' shenanigans hint that mischievous play evolved well before Homo sapiens did.