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作者:Pires, Peter Mussells; Zhang, Lingwei; Parache, Victoria; Abbott, L. F.; Maimon, Gaby
作者单位:Rockefeller University; Rockefeller University; Howard Hughes Medical Institute; Columbia University
摘要:Neuronal signals that are relevant for spatial navigation have been described in many species1-10. However, a circuit-level understanding of how such signals interact to guide navigational behaviour is lacking. Here we characterize a neuronal circuit in the Drosophila central complex that compares internally generated estimates of the heading and goal angles of the fly-both of which are encoded in world-centred (allocentric) coordinates-to generate a body-centred (egocentric) steering signal. ...
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作者:Liu, Haimeng; Liu, Jianguo
作者单位:Chinese Academy of Sciences; Institute of Geographic Sciences & Natural Resources Research, CAS; Michigan State University
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作者:Miles, Bertie W. J.; Bingham, Robert G.
作者单位:University of Edinburgh
摘要:Mass loss of the Antarctic Ice Sheet has been driven primarily by the thinning of the floating ice shelves that fringe the ice sheet1, reducing their buttressing potential and causing land ice to accelerate into the ocean2. Observations of ice-shelf thickness change by satellite altimetry stretch back only to 1992 (refs. 1,3-5) and previous information about thinning remains unquantified. However, extending the record of ice-shelf thickness change is possible by proxy, by measuring the change ...
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作者:Ciceri, Gabriele; Baggiolini, Arianna; Cho, Hyein S.; Kshirsagar, Meghana; Benito-Kwiecinski, Silvia; Walsh, Ryan M.; Aromolaran, Kelly A.; Gonzalez-Hernandez, Alberto J.; Munguba, Hermany; Koo, So Yeon; Xu, Nan; Sevilla, Kaylin J.; Goldstein, Peter A.; Levitz, Joshua; Leslie, Christina S.; Koche, Richard P.; Studer, Lorenz
作者单位:Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; Universita della Svizzera Italiana; Institute of Oncology Research (IOR); Universita della Svizzera Italiana
摘要:The pace of human brain development is highly protracted compared with most other species1-7. The maturation of cortical neurons is particularly slow, taking months to years to develop adult functions3-5. Remarkably, such protracted timing is retained in cortical neurons derived from human pluripotent stem cells (hPSCs) during in vitro differentiation or upon transplantation into the mouse brain4,8,9. Those findings suggest the presence of a cell-intrinsic clock setting the pace of neuronal ma...
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作者:Naddaf, Miryam
摘要:Implants and other technologies that decode neural activity can restore people's abilities to move and speak - and help researchers to understand how the brain works.
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作者:Brkic, Dejan
作者单位:University of Nis
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作者:Crawford, Kate
摘要:First-of-its-kind US bill would address the environmental costs of the technology, but there's a long way to go.
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作者:Barends, Thomas R. M.; Gorel, Alexander; Bhattacharyya, Swarnendu; Schiro, Giorgio; Bacellar, Camila; Cirelli, Claudio; Colletier, Jacques-Philippe; Foucar, Lutz; Gruenbein, Marie Luise; Hartmann, Elisabeth; Hilpert, Mario; Holton, James M.; Johnson, Philip J. M.; Kloos, Marco; Knopp, Gregor; Marekha, Bogdan; Nass, Karol; Nass Kovacs, Gabriela; Ozerov, Dmitry; Stricker, Miriam; Weik, Martin; Doak, R. Bruce; Shoeman, Robert L.; Milne, Christopher J.; Huix-Rotllant, Miquel; Cammarata, Marco; Schlichting, Ilme
作者单位:Max Planck Society; Centre National de la Recherche Scientifique (CNRS); Aix-Marseille Universite; Communaute Universite Grenoble Alpes; Universite Grenoble Alpes (UGA); CEA; Centre National de la Recherche Scientifique (CNRS); Swiss Federal Institutes of Technology Domain; Paul Scherrer Institute; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; European XFEL; Ecole Normale Superieure de Lyon (ENS de LYON); Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Chemistry (INC); University of Oxford; European Synchrotron Radiation Facility (ESRF)
摘要:High-intensity femtosecond pulses from an X-ray free-electron laser enable pump-probe experiments for the investigation of electronic and nuclear changes during light-induced reactions. On timescales ranging from femtoseconds to milliseconds and for a variety of biological systems, time-resolved serial femtosecond crystallography (TR-SFX) has provided detailed structural data for light-induced isomerization, breakage or formation of chemical bonds and electron transfer(1,2). However, all ultra...
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作者:Bourzac, Katherine
摘要:Engineered petunia emits a continuous green glow thanks to genes from a light-up mushroom.
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作者:Tollefson, Jeff
摘要:Jury awards Mann more than US$1 million - raising hopes for scientists who are attacked politically because of their work.