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最新文章

• Reply to Yang et al.: Synergies between photovoltaic development and innovative agricultural practices for combating desertification AI翻译
  作者：Wang, Xunming; Geng, Xin; Sun, Fubao; Han, Mengyao; Liu, Fa; Li, Chao
  作者单位：Chinese Academy of Sciences; Nanjing Institute of Geology & Paleontology, CAS; Institute of Geographic Sciences & Natural Resources Research, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS
• Disruption of a selective vesicle pool upon retrograde amnesia dissociates memory at presynaptic terminals AI翻译
  作者：Hiramatsu, Shun; Kabetani, Kaito; Kondo, Shu; Tanimoto, Hiromu
  作者单位：Tohoku University; Tokyo University of Science
  摘要：A single learning episode induces both labile and consolidated forms of aversive olfactory memory in Drosophila melanogaster. Retrograde amnesia triggered by post-learning perturbations specifically impairs the labile memory. However, synaptic mechanisms for this selectivity remain elusive. Here, we show that diverse amnestic treatments, such as concussion, commonly disrupt the presynaptic clustering of Synapsin, which is required for anesthesia-sensitive memory. Consistently, targeted knockou...
• Agile legged locomotion in reconfigurable modular robots AI翻译
  作者：Yu, Chen; Matthews, David; Wang, Jingxian; Gu, Jing; Blackiston, Douglas; Rubenstein, Michael; Kriegman, Sam
  作者单位：Northwestern University; Tufts University; Harvard University
  摘要：Legged machines are becoming increasingly agile and adaptive, but they have so far lacked the morphological diversity of legged animals, which have been rearranged and reshaped to fill millions of niches. Unlike their biological counterparts, legged machines have largely converged over the past decade to canonical quadrupedal and bipedal architectures that cannot be easily reconfigured to meet new tasks or recover from injury. Here, we introduce autonomous modular legs: agile yet minimal, sing...
• Phosphatidylinositol 4,5-bisphosphate mediates Arl4D self-interaction to promote Pak1 signaling AI翻译
  作者：Chang, Ting -Wei; Lee, Fang-Jen S.
  作者单位：National Taiwan University; National Taiwan University; National Taiwan University; National Taiwan University Hospital
  摘要：Self-association by small GTPases on membrane is critical for their signaling output and cellular function. However, a mechanistic understanding of how membrane components regulate this process remains incompletely understood. Here, we show that phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] promotes Arl4D self-association to potentiate downstream Pak1 signaling. We first show that Arl4D self-association is GTP-dependent and occurs at the plasma membrane. Fibronectin stimulation increases t...
• GalNAc-T 13 maintains neurite architecture and memory retention via O-GalNAc glycosylation of seizure protein 6 AI翻译
  作者：Deng, Yao; Zou, Xia; Zhang, Han; Lu, Xiaoyan; Zhao, Xingming; Jia, Wenjuan; Xu, Yingjiao; Yang, Fang; Narimatsu, Hisashi; Zhang, Yan
  作者单位：Shanghai Jiao Tong University; Shanghai Jiao Tong University; National Institute of Advanced Industrial Science & Technology (AIST)
  摘要：Glycosylation, a key and prevalent modification in brain proteins and lipids, is essential for brain development and function. O-GalNAc glycosylation, initiated by the family of polypeptide N-acetylgalactosaminyltransferases (GalNAc-Ts, GALNTs), is the most abundant type of O-glycosylation in the brain. Despite growing evidence linking GALNT variations to neuropsychiatric disorders, the molecular roles and underlying mechanisms by which O-GalNAc glycosylation contributes to brain functions rem...
• Reply to Pernet et al.: Mesocosm experiment reveals the carbon removal mechanisms in oyster farming AI翻译
  作者：Dong, Shuang-Lin; Kao, Shuh-Ji; Tian, Xiang-Li; Chen, Xue-Wei-Jie; Zhang, Zhou; Pan, Miao-Jun; Dong, Yun-Wei
  作者单位：Ocean University of China; Hainan University
• Wild vegetables contribute to improving the diversity and sustainability of vegetable diets in China AI翻译
  作者：Huang, Li; Huang, Linlin; Jiang, Yajie; Tian, Lijuan; Chen, Jinlong; Hu, Siwei; Zhou, Lihua; Jin, Cheng; Ma, Suhui; Jim, C. Y.; Yang, Yongchuan; Zhang, Zhiming; Tang, Zhiyao
  作者单位：Yunnan University; Yunnan University; Chongqing University; Peking University; Peking University; Sun Yat Sen University; Education University of Hong Kong (EdUHK)
  摘要：Vegetables are vital to human diets, supplying essential micronutrients critical to overall health. Despite this, it remains unclear whether current supply systems effectively ensure equitable access to cultivated vegetables across regions or fully leverage the potential of wild vegetables to diversify diets. Here, we analyzed data from 2,983 supermarkets across 330 cities for cultivated vegetables, alongside a comprehensive database of 2,461 species of wild vegetables, to evaluate the current...
• Persistent adaptation through dual-timescale regulation of ion channel properties AI翻译
  作者：Mondal, Yugarshi; Calabrese, Ronald L.; Marder, Eve
  作者单位：Brandeis University; Brandeis University; Emory University
  摘要：Neurons are terminally differentiated cells that adapt to maintain stable function over years, despite encountering a wide range of environmental perturbations. In some cases, recovery from perturbation is not shaped by prior exposure; in others, recovery depends on the neuron's perturbation history. A particularly striking form of history-dependent recovery occurs when prior exposure enhances the neuron's ability to recover from future perturbations while leaving baseline activity largely unc...
• Five decades of seasonal phytoplankton succession examined with principal traits-An approach linking composition to function AI翻译
  作者：Pranger, Anton; Diehl, Sebastian; Peeters, Frank
  作者单位：University of Konstanz; Umea University; Umea University
  摘要：Understanding how changes in community composition and function are driven by environmental change remains a fundamental challenge-to which trait-based approaches offer a mechanistic perspective. To examine links between functional and compositional changes we introduce a metric-the principal trait-relating the mean traits of a community to principal components (PC) of community composition. We demonstrate the benefits of this approach by analyzing nearly five decades of phytoplankton monitori...
• Thirty years of glacier grounding line retreat in Antarctica AI翻译
  作者：Rignot, Eric; Scheuchl, Bernd; Barre, Jean Baptiste; Brancato, Virginia; Charrier, Laurane; Chen, Hanning; Ciraci, Enrico; Dinh, Andy; Herreid, Sam; Jeong, Seongsu; Li, Xin; Mitchell, Thomas; Mohajerani, Yara; Shamsian, Sina; Tolpekin, Valentyn; Velicogna, Isabella; Wollersheim, Michael
  作者单位：University of California System; University of California Irvine; California Institute of Technology; National Aeronautics & Space Administration (NASA); NASA Jet Propulsion Laboratory (JPL); University of California System; University of California Irvine; Communaute Universite Grenoble Alpes; Centre National de la Recherche Scientifique (CNRS); Universite Grenoble Alpes (UGA); University of Washington; University of Washington Seattle
  摘要：The Grounding Line (GL)-the transition from ice grounded on the continent and ice afloat in the ocean-is a sensitive indicator of glacier stability and mass balance. Using differential synthetic aperture radar interferometry from ERS-1/2, Sentinel-1, RADARSAT-1/2, RADARSAT Constellation Mission, ALOS PALSAR-2, COSMO-SkyMed, and ICEYE, we assemble a continental scale record of grounding line migration from 1992 to 2025. Over 77 +/- 10% of Antarctic coastal length, we detect no GL migration. Ret...