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作者:Pernet, Fabrice; Boyd, Philip W.; Dupont, Sam; Gattuso, Jean-Pierre; Gazeau, Frederic; Gobler, Christopher J.; Metian, Marc; Tomasetti, Stephen; Williamson, Phillip
作者单位:Universite de Bretagne Occidentale; Ifremer; Institut de Recherche pour le Developpement (IRD); Centre National de la Recherche Scientifique (CNRS); University of Tasmania; University of Gothenburg; Marine & Freshwater Research Institute (MFRI); Sorbonne Universite; Centre National de la Recherche Scientifique (CNRS); State University of New York (SUNY) System; Stony Brook University; University System of Maryland; University of Maryland Eastern Shore; University of East Anglia
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作者:Walsh, Wes; Figueroa, Laura L.
作者单位:University of Massachusetts System; University of Massachusetts Amherst; University of Massachusetts System; University of Massachusetts Amherst
摘要:Earth is experiencing a biodiversity crisis. Among the declining taxa are insects and arachnids, which account for most of the world's animal species, and are ecologically and economically vital. Thus, understanding the factors influencing insect and arachnid conservation policies is urgently needed. Here, we review conservation assessments for 46,257 North American insect and arachnid species and examine the factors that affect state and federal legal protections for species in the United Sta...
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作者:Yang, Hong; Feng, Qi; Xiao, Jianhua; Li, Guoshuai; Thompson, Julian R.
作者单位:Chinese Academy of Sciences; Northwest Institute of Eco-Environment & Resources, CAS; University of Reading; University of London; University College London
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作者:Cho, Frankie H. T.; Agnolucci, Paolo; Bateman, Ian J.; Lee, Christopher F.; Lovett, Andrew; Mancini, Mattia C.; Rapti, Chrysanthi; Day, Brett H.
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作者:Cornell, Rebecca; Handley, Ava; Pocock, Roger
作者单位:Monash University; Monash University
摘要:The mitochondrial unfolded protein response (UPRmt) is triggered by cells to alleviate proteotoxicity in response to metabolic stress. The ability to anticipate and prime cells against mitochondrial stress, by sensing potentially toxic changes in the external or internal environment, would provide a survival advantage. Yet, whether and how animals anticipate mitochondrial stress remains unclear. Here, we show that the Caenorhabditis elegans receptor guanylyl cyclase GCY-9 regulates neuropeptid...
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作者:Li, Yaowei; Santer, Benjamin D.; Solomon, Susan; Thompson, David W. J.; Fu, Qiang
作者单位:Massachusetts Institute of Technology (MIT); University of East Anglia; Colorado State University System; Colorado State University Fort Collins; University of Washington; University of Washington Seattle
摘要:Large volcanic eruptions and intense wildfires perturb Earth's atmospheric temperature. Understanding the climate response to such natural forcings is essential for obtaining reliable estimates of its response to anthropogenic greenhouse gas emissions. While the climate impacts of volcanic sulfate aerosols are well documented, other natural forcings-including wildfire smoke reaching the stratosphere and water vapor injections from a submarine eruption-pose new challenges for detecting and attr...
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作者:Lihm, Jae-Mo; Kiese, Dominik; Lee, Seung-Sup B.; Kugler, Fabian B.
作者单位:European Theoretical Spectroscopy Facility (ETSF); Universite Catholique Louvain; Seoul National University (SNU); Seoul National University (SNU); Simons Foundation; Flatiron Institute; Seoul National University (SNU); University of Cologne
摘要:We present the finite-difference parquet method that greatly improves the applicability and accuracy of two-particle correlation approaches to interacting electron systems. This method incorporates the nonperturbative local physics from a reference solution and builds all parquet diagrams while circumventing potentially divergent irreducible vertices. Its unbiased treatment of different fluctuations is crucial for reproducing the strong-coupling pseudogap in the underdoped Hubbard model, consi...
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作者:Orr, Nicholas H. P.; Le Gof, Magali; Yiming, Burebi; Barrat, Jean-Louis; Bouzid, Mehdi; Ramos, Laurence; Creton, Costantino; Martens, Kirsten; Cipelletti, Luca
作者单位:Universite de Montpellier; Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Universite PSL; Centre National de la Recherche Scientifique (CNRS); Ecole Normale Superieure (ENS); Communaute Universite Grenoble Alpes; Centre National de la Recherche Scientifique (CNRS); Universite Grenoble Alpes (UGA); University of Innsbruck; Sorbonne Universite; Universite PSL; Centre National de la Recherche Scientifique (CNRS); Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI); CNRS - Institute of Chemistry (INC); Centre National de la Recherche Scientifique (CNRS); Communaute Universite Grenoble Alpes; Universite Grenoble Alpes (UGA); Institut National Polytechnique de Grenoble; Institut Universitaire de France
摘要:Multiple polymer networks, such as double-network elastomers comprising a sacrificial and a matrix network, exhibit exceptional mechanical resilience, commonly attributed to the formation of an extended damage zone before a crack can grow. However, the microscopic mechanisms underlying their toughness remain poorly understood. Here, we combine advanced light scattering methods and molecular dynamics simulations to explore the microscopic relaxation dynamics and stress redistribution at the pol...
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作者:Szewczyk, Paul; Greene, Nicholas P.; Symmons, Martyn F.; Hardwick, Steven W.; Koronakis, Vassilis
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作者:Wang, Jian; V. Dokholyan, Nikolay
作者单位:University of Virginia; University of Virginia (UVA) Health System; University of Virginia (UVA) Health System; University of Virginia; University of Virginia
摘要:Predicting small molecule binding sites on proteins remains a key challenge in structure-based drug discovery. While AlphaFold3 has transformed protein structure prediction, accurate identification of functional sites such as ligand binding pockets remains a distinct and unresolved problem. Graph neural networks have emerged as promising tools for this task, but most current approaches focus on local structural features and are trained on relatively small datasets, limiting their ability to mo...