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作者:Sun, Wenxiang; Hughes, Erik P.; Kim, Heejoo; Perovanovic, Jelena; Charley, Krystal R.; Perkins, Bryant; Du, Junhong; Ibarra, Andrea; Syage, Amber R.; Hale, J. Scot; Williams, Matthew A.; Tantin, Dean
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作者:Michimori, Yuta; Izaki, Rikihisa; Su, Yu; Fukuyama, Yuto; Shimamura, Shigeru; Nishimura, Karin; Miwa, Yuya; Hamakita, Sotaro; Shimosaka, Takahiro; Makino, Yuki; Takeno, Ryo; Sato, Takaaki; Beppu, Haruki; Cann, Isaac; Kanai, Tamotsu; Nunoura, Takuro; Atomi, Haruyuki
作者单位:Kyoto University; Kyoto University; Japan Agency for Marine-Earth Science & Technology (JAMSTEC); Japan Agency for Marine-Earth Science & Technology (JAMSTEC); Kyoto University; University of Illinois System; University of Illinois Urbana-Champaign
摘要:Many organisms that utilize the Calvin-Benson-Bassham (CBB) cycle for autotrophic growth harbor metabolic pathways to remove and/or salvage 2- phosphoglycolate, the product of the oxygenase activity of ribulose-1,5- bisphosphate carboxylase/oxygenase (Rubisco). It has been presumed that the occurrence of 2- phosphoglycolate salvage is linked to the CBB cycle, and in particular, the C2 pathway to the CBB cycle and oxygenic photosynthesis. Here, we examined 2- phosphoglycolate salvage in the hyp...
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作者:Weaver, Davis T.; King, Eshan S.; Maltas, Jeff; Scott, Jacob G.
作者单位:University System of Ohio; Case Western Reserve University; Cleveland Clinic Foundation; University System of Ohio; Case Western Reserve University
摘要:Antimicrobial resistance was estimated to be associated with 4.95 million deaths worldwide in 2019. It is possible to frame the antimicrobial resistance problem as a feedback -control problem. If we could optimize this feedback -control problem and translate our findings to the clinic, we could slow, prevent, or reverse the development of high-level drug resistance. Prior work on this topic has relied on systems where the exact dynamics and parameters were known a priori. In this study, we ext...
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作者:Michaeli, Tal Falick; Sabag, Ofra; Azria, Batia; Fok, Rimma; Abudi, Nathalie; Abramovitch, Rinat; Monin, Jonathan; Gielchinsky, Yuval; Cedar, Howard; Bergman, Yehudit
作者单位:Hebrew University of Jerusalem; Hadassah University Medical Center; Hebrew University of Jerusalem; Hadassah University Medical Center; Hebrew University of Jerusalem; Hadassah University Medical Center; Hebrew University of Jerusalem; Hadassah University Medical Center; Hebrew University of Jerusalem; Hebrew University of Jerusalem; Hadassah University Medical Center; Tel Aviv University; Rabin Medical Center
摘要:As a result of partial hepatectomy, the remaining liver tissue undergoes a process of renewed proliferation that leads to rapid regeneration of the liver. By following the early stages of this process, we observed dramatic programmed changes in the DNA methylation profile, characterized by both de novo and demethylation events, with a subsequent return to the original adult pattern as the liver matures. Strikingly, these transient alterations partially mimic the DNA methylation state of embryo...
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作者:Qu, Wei; Tang, Zhuoyun; Tang, Su; Zhong, Tao; Zhao, Huinan; Tian, Shuanghong; Shu, Dong; He, Chun
作者单位:Sun Yat Sen University; South China Normal University
摘要:The advancement of atomically precise dinuclear heterogeneous catalysts holds great potential in achieving efficient catalytic ozonation performance and contributes to the understanding of synergy mechanisms during reaction conditions. Herein, we demonstrate a ship - in - a- bottle and pyrolysis strategy that utilizes Fe2(CO)9 dinuclear- cluster to precisely construct Fe2 site, consisting of two Fe1-N3 units connected by Fe - Fe bonds and firmly bonded to N - doped carbon. Systematic character...
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作者:van Brussel, Leonard D.; Boksem, Maarten A. S.; Dietvorst, Roeland C.; Smidts, Ale
作者单位:Erasmus University Rotterdam; Erasmus University Rotterdam - Excl Erasmus MC
摘要:A major aspiration of investors is to better forecast stock performance. Interestingly, emerging neuroforecasting research suggests that brain activity associated with anticipatory reward relates to market behavior and population - wide preferences, including stock price dynamics. In this study, we extend these findings to professional investors processing comprehensive real - world information on stock investment options while making predictions of long - term stock performance. Using functio...