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作者:Li, Dazhi; Rocha-Roa, Cristian; Schilling, Matthew A.; Reinisch, Karin M.; Vanni, Stefano
作者单位:Yale University; University of Fribourg; University of Fribourg
摘要:Glycerophospholipids are synthesized primarily in the cytosolic leaflet of the endoplasmic reticulum (ER) membrane and must be equilibrated between bilayer leaflets to allow the ER and membranes derived from it to grow. Lipid equilibration is facilitated by integral membrane proteins called scramblases. These proteins feature a hydrophilic groove allowing the polar heads of lipids to traverse the hydrophobic membrane interior, similar to a credit card moving through a reader. Nevertheless, des...
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作者:Que, Lanfang; Yu, Fuda; Wu, Jihuai; Lan, Zhang; Feng, Yutong; Zhao, Ruizheng; Sun, Zhihao; Yang, Zhuo; Luo, Hao; Chao, Dongliang
作者单位:Huaqiao University; Fudan University; Xiamen University of Technology
摘要:Voltage oscillation at subzero in sodium - ion batteries (SIBs) has been a common but overlooked scenario, almost yet to be understood. For example, the phenomenon seriously deteriorates the performance of Na3V2(PO4)3 (NVP) cathode in PC (propylene carbonate)/EC (ethylene carbonate) - based electrolyte at -20 degrees C. Here, the correlation between voltage oscillation, structural evolution, and electrolytes has been revealed based on theoretical calculations, in- /ex - situ techniques, and cr...
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作者:Bo, Yanan; Wang, Yongqiang
作者单位:Clemson University
摘要:Distributed nonconvex optimization underpins key functionalities of numerous distributed systems, ranging from power systems, smart buildings, cooperative robots, vehicle networks to sensor networks. Recently, it has also merged as a promising solution to handle the enormous growth in data and model sizes in deep learning. A fundamental problem in distributed nonconvex optimization is avoiding convergence to saddle points, which significantly degrade optimization accuracy. We find that the pro...
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作者:Chevee, Victoria; Hullahalli, Karthik; Dailey, Katherine G.; Guereca, Leslie; Zhang, Chenyu; Waldor, Matthew K.; Portnoy, Daniel A.
作者单位:University of California System; University of California Berkeley; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Harvard University; Harvard Medical School; Howard Hughes Medical Institute; University of California System; University of California Berkeley
摘要:Listeria monocytogenes is a bacterial pathogen that can cause life - threatening central nervous system (CNS) infections. While mechanisms by which L. monocytogenes and other pathogens traffic to the brain have been studied, a quantitative understanding of the underlying dynamics of colonization and replication within the brain is lacking. In this study, we used barcoded L. monocytogenes to quantify the bottlenecks and dissemination patterns that lead to cerebral infection. Following intraveno...
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作者:Lin, Qi; Zhang, Ke; Giguet- Covex, Charline; Arnaud, Fabien; McGowan, Suzanne; Gielly, Ludovic; Capo, Eric; Huang, Shixin; Ficetola, Gentile Francesco; Shen, Ji; Dearing, John A.; Meadows, Michael E.
作者单位:Chinese Academy of Sciences; Nanjing Institute of Geography & Limnology, CAS; Centre National de la Recherche Scientifique (CNRS); Universite Savoie Mont Blanc; Royal Netherlands Academy of Arts & Sciences; Netherlands Institute of Ecology (NIOO-KNAW); Communaute Universite Grenoble Alpes; Universite Grenoble Alpes (UGA); Centre National de la Recherche Scientifique (CNRS); Universite Savoie Mont Blanc; Umea University; University of Milan; Nanjing University; University of Southampton; University of Cape Town
摘要:Understanding the transient dynamics of interlinked social-ecological systems (SES) is imperative for assessing sustainability in the Anthropocene. However, how to identify critical transitions in real - world SES remains a formidable challenge. In this study, we present an evolutionary framework to characterize these dynamics over an extended historical timeline. Our approach leverages multidecadal rates of change in socioeconomic data, paleoenvironmental, and cutting - edge sedimentary ancie...
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作者:Wang, Zhongxuan; Wang, Qian; Gong, Weiyi; Chen, Amy; Islam, Abdullah; Quan, Lina; Woehl, Taylor J.; Yan, Qimin; Ren, Shenqiang
作者单位:University System of Maryland; University of Maryland College Park; Virginia Polytechnic Institute & State University; Northeastern University; Virginia Polytechnic Institute & State University; University System of Maryland; University of Maryland College Park
摘要:Growing crystallographically incommensurate and dissimilar organic materials is fundamentally intriguing but challenging for the prominent cross - correlation phenomenon enabling unique magnetic, electronic, and optical functionalities. Here, we report the growth of molecular layered magnetin - ferroelectric crystals, demonstrating photo manipulation of interfacial ferroic coupling. The heterocrystals exhibit striking photomagnetization and magnetoelectricity, resulting in photomultiferroic co...
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作者:Backholm, Matilda; Karki, Tytti; Nurmi, Heikki A.; Vuckovac, Maja; Turkki, Valtteri; Lepikko, Sakari; Jokinen, Ville; Quere, David; Timonen, Jaakko V. I.; Ras, Robin H. A.
作者单位:Aalto University; Aalto University; Aalto University; Universite PSL; Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI); Sorbonne Universite; Universite Paris Cite
摘要:Superhydrophobic surfaces are often seen as frictionless materials, on which water is highly mobile. Understanding the nature of friction for such water - repellent systems is central to further minimize resistance to motion and energy loss in applications. For slowly moving drops, contact - line friction has been generally considered dominant on slippery superhydrophobic surfaces. Here, we show that this general rule applies only at very low speed. Using a micropipette force sensor in an osci...
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作者:Koch, Alexander K.; Monster, Dan; Nafziger, Julia
作者单位:Aarhus University
摘要:We present an experiment on the immediate and lasting effects of reminder nudges in a complex environment. In the study, 1,542 subjects face a setting where, within a brief time frame, they have to pay attention to and perform multiple actions in a computer game. The experiment investigates i) the effect of reminders on the reminded actions and their spillovers on nonreminded actions; ii) spillovers between multiple nudges when the number of reminded actions is increased; and iii) intertempora...
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作者:Lee, Yuan; Dai, Wenhan; Towsley, Don; Englund, Dirk
作者单位:Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); University of Massachusetts System; University of Massachusetts Amherst; Massachusetts Institute of Technology (MIT)
摘要:The central aim of quantum networks is to facilitate user connectivity via quantum channels, but there is an open need for benchmarking metrics to compare diverse quantum networks. Here, we propose a general framework for quantifying the performance of a quantum network by estimating the value created by connecting users through quantum channels. In this framework, we define the quantum network utility metric U QN to capture the social and economic value of quantum networks. The proposed frame...
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作者:Muenzel, Dominic; Bani, Alessia; De Brauwer, Maarten; Stewart, Eleanor; Djakiman, Cilun; Halwi; Purnama, Ray; Yusuf, Syafyuddin; Santoso, Prakas; Hukom, Frensly D.; Struebig, Matthew; Jompa, Jamaluddin; Limmon, Gino; Dumbrell, Alex; Beger, Maria
作者单位:University of Leeds; University of Kent; University of Essex; University of Derby; Commonwealth Scientific & Industrial Research Organisation (CSIRO); Universitas Pattimura; Universitas Hasanuddin; Universitas Hasanuddin; Bogor Agricultural University; Universitas Pattimura; University of Queensland
摘要:Environmental DNA (eDNA) metabarcoding has the potential to revolutionize conservation planning by providing spatially and taxonomically comprehensive data on biodiversity and ecosystem conditions, but its utility to inform the design of protected areas remains untested. Here, we quantify whether and how identifying conservation priority areas within coral reef ecosystems differs when biodiversity information is collected via eDNA analyses or traditional visual census records. We focus on 147 ...