18期

最新文章

• Evolution of homologous recombination rates across bacteria AI翻译
  作者：Torrance, Ellis L.; Burton, Corey; Diop, Awa; Bobay, Louis-Marie
  作者单位：University of North Carolina; University of North Carolina Greensboro; North Carolina State University
  摘要：Bacteria are nonsexual organisms but are capable of exchanging DNA at diverse degrees through homologous recombination. Intriguingly, the rates of recombination vary immensely across lineages where some species have been described as purely clonal and others as quasi-sexual. However, estimating recombination rates has proven a difficult endeavor and estimates often vary substantially across studies. It is unclear whether these variations reflect natural variations across populations or are due...
• Low-latency gravitational wave alert products and their performance at the time of the fourth LIGO-Virgo-KAGRA observing run AI翻译
  作者：Chaudhary, Sushant Sharma; Toivonen, Andrew; Waratkar, Gaurav; Mo, Geoffrey; Chatterjee, Deep; Antier, Sarah; Brockill, Patrick; Coughlin, Michael W.; Essick, Reed; Ghosh, Shaon; Morisaki, Soichiro; Baral, Pratyusava; Baylor, Amanda; Adhikari, Naresh; Brady, Patrick; Davies, Gareth Cabourn; Dal Canton, Tito; Cavaglia, Marco; Creighton, Jolien; Choudhary, Sunil; Chu, Yu-Kuang; Clearwater, Patrick; Davis, Luke; Dent, Thomas; Drago, Marco; Ewing, Becca; Godwin, Patrick; Guo, Weichangfeng; Hanna, Chad; Huxford, Rachael; Harry, Ian; Katsavounidis, Erik; Kovalam, Manoj; Li, Alvin K. Y.; Magee, Ryan; Marx, Ethan; Meacher, Duncan; Messick, Cody; Atkinson, Xan Morice; Pace, Alexander; De Pietri, Roberto; Piotrzkowski, Brandon; Roy, Soumen; Sachdev, Surabhi; Singer, Leo P.; Singh, Divya; Bahcall, Neta; Szczepanczyk, Marek; Tang, Daniel; Trevor, Max; Tsukada, Leo; Villa-Ortega, Veronica; Wen, Linqing; Wysocki, Daniel
  作者单位：University of Missouri System; Missouri University of Science & Technology; University of Minnesota System; University of Minnesota Twin Cities; Indian Institute of Technology System (IIT System); Indian Institute of Technology (IIT) - Bombay; Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); Universite Cote d'Azur; Observatoire de la Cote d'Azur; University of Wisconsin System; University of Wisconsin Milwaukee; University of Toronto; University of Toronto; University of Toronto; Montclair State University; University of Tokyo; University of Portsmouth; Universite Paris Cite; Universite Paris Saclay; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute of Nuclear and Particle Physics (IN2P3); University of Wisconsin System; University of Wisconsin Milwaukee; University of Western Australia; Universidade de Santiago de Compostela; Sapienza University Rome; Istituto Nazionale di Fisica Nucleare (INFN); Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; California Institute of Technology; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; University of Portsmouth; University of Parma; Istituto Nazionale di Fisica Nucleare (INFN); FOM National Institute for Subatomic Physics; Utrecht University; University System of Georgia; Georgia Institute of Technology; National Aeronautics & Space Administration (NASA); NASA Goddard Space Flight Center; University System of Maryland; University of Maryland College Park; State University System of Florida; University of Florida; University System of Maryland; University of Maryland College Park
  摘要：Multimessenger searches for binary neutron star (BNS) and neutron star-black hole (NSBH) mergers are currently one of the most exciting areas of astronomy. The search for joint electromagnetic and neutrino counterparts to gravitational wave (GW)s has support this effort, public semiautomated data products are sent in near real-time and include localization and source properties to guide complementary observations. In preparation for O4, we have conducted a study using a simulated population of...
• Machine learning enables identification of an alternative yeast galactose utilization pathway AI翻译
  作者：Harrison, Marie-Claire; Ubbelohde, Emily J.; LaBella, Abigail L.; Opulente, Dana A.; Wolters, John F.; Zhou, Xiaofan; Shen, Xing-Xing; Groenewald, Marizeth; Hittinger, Chris Todd; Rokas, Antonis
  作者单位：Vanderbilt University; Vanderbilt University; United States Department of Energy (DOE); University of Wisconsin System; University of Wisconsin Madison; University of North Carolina; University of North Carolina Charlotte; Villanova University; South China Agricultural University; Zhejiang University
  摘要：How genomic differences contribute to phenotypic differences is a major question in biology. The recently characterized genomes, isolation environments, and qualitative species (nearly all known) in the yeast subphylum Saccharomycotina provide a powerful, yet complex, dataset for addressing this question. We used a random forest algorithm trained on these genomic, metabolic, and environmental data to predict growth on several carbon sources with high accuracy. Known structural genes involved i...
• Mapping seasonal migration in a songbird hybrid zone --heritability, genetic correlations, and genomic patterns linked to speciation AI翻译
  作者：Justen, Hannah C.; Easton, Wendy E.; Delmore, Kira E.
  作者单位：Environment & Climate Change Canada
  摘要：Seasonal migration is a widespread behavior relevant for adaptation and speciation, yet knowledge of its genetic basis is limited. We leveraged advances in tracking and sequencing technologies to bridge this gap in a well - characterized hybrid zone between songbirds that differ in migratory behavior. Migration requires the coordinated action of many traits, including orientation, timing, and wing morphology. We used genetic mapping to show these traits are highly heritable and genetically cor...
• Sustainable, low- cost, high- contrast electrochromic displays via host-guest interactions AI翻译
  作者：Wang, Yuyang; Lei, Chuxin; Guan, Weixin; Shi, Wen; Shen, Ruipeng; Zhang, Sean Xiao- An; Yu, Guihua
  作者单位：University of Texas System; University of Texas Austin; University of Texas System; University of Texas Austin; Jilin University
  摘要：Electrochromic (EC) displays with electronically regulating the transmittance of solar radiation offer the opportunity to increase the energy efficiency of the building and electronic products and improve the comfort and lifestyle of people. Despite the unique merit and vast application potential of EC technologies, long - awaited EC windows and related visual content displays have not been fully commercialized due to unsatisfactory production cost, durability, color, and complex fabrication p...
• Maximum entropy determination of mammalian proteome dynamics AI翻译
  作者：Dear, Alexander J.; Garcia, Gonzalo A.; Meisl, Georg; Collins, Galen A.; Knowles, Tuomas P. J.; Goldberg, Alfred L.
  作者单位：Harvard University; Harvard Medical School; University of Cambridge; Mississippi State University; University of Cambridge
  摘要：Full understanding of proteostasis and energy utilization in cells will require knowledge of the fraction of cell proteins being degraded with different half-lives and their rates of synthesis. We therefore developed a method to determine such information that combines mathematical analysis of protein degradation kinetics obtained in pulse-chase experiments with Bayesian data fitting using the maximum entropy principle. This approach will enable rapid analyses of whole-cell protein dynamics in...
• Individual transcription factors modulate both the micromovement of chromatin and its long- range structure AI翻译
  作者：Shaban, Haitham A.; Friman, Elias T.; Deluz, Cedric; Tollenaere, Armelle; Katanayeva, Natalya; Suter, David M.
  作者单位：Swiss School of Public Health (SSPH+); Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Egyptian Knowledge Bank (EKB); National Research Centre (NRC); UK Research & Innovation (UKRI); Medical Research Council UK (MRC); University of Edinburgh; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Swiss Institute Experimental Cancer Research; Swiss School of Public Health (SSPH+); University of Geneva
  摘要：The control of eukaryotic gene expression is intimately connected to highly dynamic chromatin structures. Gene regulation relies on activator and repressor transcription factors (TFs) that induce local chromatin opening and closing. However, it is unclear how nucleuswide chromatin organization responds dynamically to the activity of specific TFs. Here, we examined how two TFs with opposite effects on local chromatin accessibility modulate chromatin dynamics nucleuswide. We combine high - resol...
• Enriching surface- ordered defects on WO3 for photocatalytic CO2-to-CH4 conversion by water AI翻译
  作者：Xue, Sikang; Wei, Changgeng; Shen, Min; Liang, Xiaocong; Wang, Jiali; Yang, Can; Xing, Wandong; Wang, Sibo; Lin, Wei; Yu, Zhiyang; Hou, Yidong; Yu, Jimmy C.; Wang, Xinchen
  作者单位：Fuzhou University; Fuzhou University; Chinese University of Hong Kong
  摘要：Defect engineering has been widely applied in semiconductors to improve photocatalytic properties by altering the surface structures. This study is about the transformation of inactive WO 3 nanosheets to a highly effective CO 2 - to - CH 4 conversion photocatalyst by introducing surface - ordered defects in abundance. The nonstoichiometric WO 3 - x samples were examined by using aberration - corrected electron microscopy. Results unveil abundant surface - ordered terminations derived from the ...
• AI model disgorgement: Methods and choices AI翻译
  作者：Achille, Alessandro; Kearns, Michael; Klingenberg, Carson; Soatto, Stefano
  作者单位：University of Pennsylvania; University of California System; University of California Los Angeles
  摘要：Over the past few years, machine learning models have significantly increased in size and complexity, especially in the area of generative AI such as large language models. These models require massive amounts of data and compute capacity to train, to the extent that concerns over the training data (such as protected or private content) cannot be practically addressed by retraining the model from scratch with the questionable data removed or altered. Furthermore, despite significant efforts an...
• Mortality and morbidity ramifications of proposed retractions in healthcare coverage for the United States AI翻译
  作者：Pandey, Abhishek; Fitzpatrick, Meagan C.; Singer, Burton H.; Galvani, Alison P.
  作者单位：Yale University; University System of Maryland; University of Maryland Baltimore; State University System of Florida; University of Florida
  摘要：In the absence of universal healthcare in the United States, federal programs of Medicaid and Medicare are vital to providing healthcare coverage for low - income households and elderly individuals, respectively. However, both programs are under threat, with either enacted or proposed retractions. Specifically, raising Medicare age eligibility and the addition of work requirements for Medicaid qualification have been proposed, while termination of continuous enrollment for Medicaid was recentl...