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作者：Thibodeau, Patricia S.; Puggioni, Gavino; Strock, Jacob; Borkman, David G.; Rynearson, Tatiana A.
作者单位：University of Rhode Island; University of Rhode Island; University of New England - Maine
摘要：Long - term ecological time series provide a unique perspective on the emergent properties of ecosystems. In aquatic systems, phytoplankton form the base of the food web and their biomass, measured as the concentration of the photosynthetic pigment chlorophyll a (chl a ), is an indicator of ecosystem quality. We analyzed temporal trends in chl a from the Long - Term Plankton Time Series in Narragansett Bay, Rhode Island, USA, a temperate estuary experiencing long - term warming and changing an...
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作者：Wendt, Kathleen A.; Nehrbass-Ahles, Christoph; Niezgoda, Kyle; Noone, David; Kalk, Michael; Menviel, Laurie; Gottschalk, Julia; Rae, James W. B.; Schmitt, Jochen; Fischer, Hubertus; Stocker, Thomas F.; Muglia, Juan; Ferreira, David; Marcott, Shaun A.; Brook, Edward; Buizert, Christo
作者单位：Oregon State University; University of Bern; University of Bern; National Physical Laboratory - UK; University of New South Wales Sydney; University of Kiel; University of St Andrews; Centro Nacional Patagonico (CENPAT); Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET); University of Reading; University of Wisconsin System; University of Wisconsin Madison
摘要：The last glacial period was punctuated by cold intervals in the North Atlantic region that culminated in extensive iceberg discharge events. These cold intervals, known as Heinrich Stadials, are associated with abrupt climate shifts worldwide. Here, we present CO 2 measurements from the West Antarctic Ice Sheet Divide ice core across Heinrich Stadials 2 to 5 at decadal - scale resolution. Our results reveal multi - decadal - scale jumps in atmospheric CO 2 concentrations within each Heinrich S...
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作者：Calabrese, Ludovico; Ciandrini, Luca; Lagomarsino, Marco Cosentino
作者单位：IFOM - FIRC Institute of Molecular Oncology; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite de Montpellier; Centre National de la Recherche Scientifique (CNRS); Institut Universitaire de France; University of Milan; Istituto Nazionale di Fisica Nucleare (INFN)
摘要：Experimental observations tracing back to the 1960s imply that ribosome quantities play a prominent role in determining a cell's growth. Nevertheless, in biologically relevant scenarios, growth can also be influenced by the levels of mRNA and RNA polymerase. Here, we construct a quantitative model of biosynthesis providing testable scenarios for these situations. The model explores a theoretically motivated regime where RNA polymerases compete for genes and ribosomes for transcripts and gives ...
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作者：Shankar, Suraj; Scharrer, Luca V. D.; Bowick, Mark J.; Marchetti, M. Cristina
作者单位：Harvard University; University of Michigan System; University of Michigan; University of California System; University of California Santa Barbara; University of Chicago; University of California System; University of California Santa Barbara
摘要：Topological defects play a central role in the physics of many materials, including magnets, superconductors, and liquid crystals. In active fluids, defects become autonomous particles that spontaneously propel from internal active stresses and drive chaotic flows stirring the fluid. The intimate connection between defect textures and active flow suggests that properties of active materials can be engineered by controlling defects, but design principles for their spatiotemporal control remain ...
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作者：Fu, Haochen; Fei, Chenyi; Ouyang, Qi; Tu, Yuhai
作者单位：University of California System; University of California San Diego; Massachusetts Institute of Technology (MIT); Peking University; International Business Machines (IBM); IBM USA
摘要：Nearly all circadian clocks maintain a period that is insensitive to temperature changes, a phenomenon known as temperature compensation (TC). Yet, it is unclear whether there is any common feature among different systems that exhibit TC. From a general timescale invariance, we show that TC relies on the existence of certain periodlengthening reactions wherein the period of the system increases strongly with the rates in these reactions. By studying several generic oscillator models, we show t...
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作者：Mizera, Jiri; Strunga, Vladimir
作者单位：Czech Academy of Sciences; Nuclear Physics Institute of the Czech Academy of Sciences; Czech Academy of Sciences; Institute of Rock Structure & Mechanics of the Czech Academy of Sciences
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作者：Li, Heyang; Tessone, Claudio J.; Zeng, An
作者单位：Beijing Normal University; University of Zurich; University of Zurich
摘要：While scientific researchers often aim for high productivity, prioritizing the quantity of publications may come at the cost of time and effort dedicated to individual research. It is thus important to examine the relationship between productivity and disruption for individual researchers. Here, we show that with the increase in the number of published papers, the average citation per paper will be higher yet the mean disruption of papers will be lower. In addition, we find that the disruption...
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作者：Chan, Brian; Rubinstein, Michael
作者单位：Duke University; Duke University; Duke University; Duke University; Hokkaido University
摘要：In mammalian cells, the cohesin protein complex is believed to translocate along chromatin during interphase to form dynamic loops through a process called active loop extrusion. Chromosome conformation capture and imaging experiments have suggested that chromatin adopts a compact structure with limited interpenetration between chromosomes and between chromosomal sections. We developed a theory demonstrating that active loop extrusion causes the apparent fractal dimension of chromatin to cross...
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作者：Darlow, Ben; Gray, Ben
作者单位：University of Otago
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作者：Fagin, Ronald; Riegel, Ryan; Gray, Alexander
作者单位：International Business Machines (IBM); IBM USA; International Business Machines (IBM); IBM USA
摘要：Interest in logics with some notion of real -valued truths has existed since at least Boole and has been increasing in AI due to the emergence of neuro-symbolic approaches, though often their logical inference capabilities are characterized only qualitatively. We provide foundations for establishing the correctness and power of such systems. We introduce a rich class of multidimensional sentences, with a sound and complete axiomatization that can be parameterized to cover many real -valued log...
