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作者:He, Ye; Dai, Sheng; Sheng, Jianping; Ren, Qin; Lv, Yao; Sun, Yanjuan; Dong, Fan
作者单位:University of Electronic Science & Technology of China; University of Electronic Science & Technology of China; East China University of Science & Technology
摘要:The photocatalytic CO2- to- CH4 conversion involves multiple consecutive proton- electron coupling transfer processes. Achieving high CH4 selectivity with satisfactory conversion efficiency remains challenging since the inefficient proton and electron delivery path results in sluggish proton-electron transfer kinetics. Herein, we propose the fabrication of atomically adjacent anion-cation vacancy as paired redox active sites that could maximally promote the proton- and electron- donating effic...
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作者:Salgado, Magdiel; Marquez-Miranda, Valeria; Ferrada, Luciano; Rojas, Maximiliano; Poblete-Flores, Gonzalo; Gonzalez-Nilo, Fernando D.; Ardiles, Alvaro O.; Saez, Juan C.
作者单位:Universidad de Valparaiso; Universidad Andres Bello; Universidad de Concepcion; Universidad de Valparaiso
摘要:Pannexin1 hemichannels (Panx1 HCs) are found in the membrane of most mammalian cells and communicate the intracellular and extracellular spaces, enabling the passive transfer of ions and small molecules. They are involved in physiological and pathophysiological conditions. During apoptosis, the C-terminal tail of Panx1 is proteolytically cleaved, but the permeability features of hemichannels and their role in cell death remain elusive. To address these topics, HeLa cells transfected with full-...
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作者:Vernet, Marlone; Fauve, Stephan; Gissinger, Christophe
作者单位:Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Ecole Normale Superieure de Lyon (ENS de LYON); Universite PSL; Ecole Normale Superieure (ENS); Universite Paris Cite; Institut Universitaire de France
摘要:We present experimental evidence of a thermoelectric effect at the interface between two liquid metals. Using superimposed layers of mercury and gallium in a cylindrical vessel operating at room temperature, we provide a direct measurement of the electric current generated by the presence of a thermal gradient along a liquid-liquid interface. At the interface between two liquids, temperature gradients induced by thermal convection lead to a complex geometry of electric currents, ultimately gen...
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作者:Boffi, Nicholas M.; Vanden-Eijnden, Eric
作者单位:New York University
摘要:Active matter systems, from self-propelled colloids to motile bacteria, are characterized by the conversion of free energy into useful work at the microscopic scale. They involve physics beyond the reach of equilibrium statistical mechanics, and a persistent challenge has been to understand the nature of their nonequilibrium states. The entropy production rate and the probability current provide quantitative ways to do so by measuring the breakdown of time -reversal symmetry. Yet, their effici...
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作者:Greenwich, Jennifer L.; Eagan, Justin L.; Feirer, Nathan; Boswinkle, Kaleb; Minasov, George; Shuvalova, Ludmilla; Inniss, Nicole L.; Raghavaiah, Jakka; Ghosh, Arun K.; Satchell, Karla J. F.; Allen, Kylie D.; Fuqua, Clay
作者单位:Indiana University System; Indiana University Bloomington; Virginia Polytechnic Institute & State University; Northwestern University; Feinberg School of Medicine; Northwestern University; Feinberg School of Medicine; Northwestern University; Feinberg School of Medicine; Purdue University System; Purdue University; Purdue University System; Purdue University
摘要:Biofilm formation and surface attachment in multiple Alphaproteobacteria is driven by unipolar polysaccharide (UPP) adhesins. The pathogen Agrobacterium tumefaciens produces a UPP adhesin, which is regulated by the intracellular second messenger cyclic diguanylate monophosphate (c- di- GMP). Prior studies revealed that DcpA, a diguanylate cyclase- phosphodiesterase, is crucial in control of UPP production and surface attachment. DcpA is regulated by PruR, a protein with distant similarity to e...
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作者:Ravindran, Sandeep
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作者:Liu, Bing-Qi; Bao, Xi-Yu; Yan, Jin-Yang; Zhang, Dan; Sun, Xiang; Li, Chu-Qiao; Chen, Zhan-Bo; Luan, Jun-Bo
作者单位:Shenyang Agricultural University
摘要:Heritable symbionts are common among animals in nature, but the molecular mechanisms underpinning symbiont invasions of host populations have been elusive. In this study, we demonstrate the spread of Rickettsia in an invasive agricultural pest, the whitefly Bemisia tabaci Mediterranean (MED), across northeastern China from 2018 to 2023. Here, we show that the beneficial symbiont Rickettsia spreads by manipulating host hormone signals. Our analyses suggest that Rickettsia have been horizontally...
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作者:Bienvenu, Arthur; Burette, Melanie; Cantet, Franck; Gourdelier, Manon; Swain, Jitendriya; Cazevieille, Chantal; Clemente, Tatiana; Sadi, Arif; Dupont, Claire; Le Fe, Manon; Bonetto, Nicolas; Bordignon, Benoit; Muriaux, Delphine; Gilk, Stacey; Bonazzi, Matteo; Martinez, Eric
作者单位:Centre National de la Recherche Scientifique (CNRS); Universite de Montpellier; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite de Montpellier; University of Nebraska System; University of Nebraska Medical Center; Universite de Montpellier; Institut National de la Sante et de la Recherche Medicale (Inserm); Centre National de la Recherche Scientifique (CNRS)
摘要:Intracellular bacterial pathogens divert multiple cellular pathways to establish their niche and persist inside their host. Coxiella burnetii , the causative agent of Q fever, secretes bacterial effector proteins via its Type 4 secretion system to generate a Coxiella - containing vacuole (CCV). Manipulation of lipid and protein trafficking by these effectors is essential for bacterial replication and virulence. Here, we have characterized the lipid composition of CCVs and found that the effect...
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作者:Chen, Ming; Wang, Yekai; Dalal, Roopa; Du, Jianhai; Vollrath, Douglas
作者单位:Stanford University; West Virginia University; West Virginia University; Stanford University
摘要:Loss of mitochondrial electron transport complex (ETC) function in the retinal pigment epithelium (RPE) in vivo results in RPE dedifferentiation and progressive photoreceptor degeneration, and has been implicated in the pathogenesis of age - related macular degeneration. Xenogenic expression of alternative oxidases in mammalian cells and tissues mitigates phenotypes arising from some mitochondrial electron transport defects, but can exacerbate others. We expressed an alternative oxidase from C...
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作者:Costigliola, Lorenzo; Hecksher, Tina; Dyre, Jeppe C.
作者单位:Roskilde University