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作者:Wiseglass, Gil; Boni, Nadir; Smorodinsky-Atias, Karina; Rubinstein, Rotem
作者单位:Tel Aviv University; Tel Aviv University
摘要:In the developing human brain, only 53 stochastically expressed clustered protocadherin (cPcdh) isoforms enable neurites from individual neurons to recognize and self- avoid while simultaneously maintaining contact with neurites from other neurons. Cell assays have demonstrated that self-- recognition occurs only when all cPcdh isoforms perfectly match across the cell boundary, with a single mismatch in the cPcdh expression profile interfering with recognition. It remains unclear, however, how...
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作者:Zomer, Aldert; Ingham, Colin J.; von Meijenfeldt, F. A. Bastiaan; Doncel, alvaro Escobar; van de Kerkhof, Gea T.; Hamidjaja, Raditijo; Schouten, Sanne; Schertel, Lukas; Mueller, Karin H.; Caton, Laura; Hahnke, Richard L.; Bolhuis, Henk; Vignolini, Silvia; Dutilh, Bas E.
作者单位:Utrecht University; Utrecht University; Utrecht University; Royal Netherlands Institute for Sea Research (NIOZ); University of Cambridge; University of Fribourg; University of Cambridge; Leibniz Association; Leibniz Institut fur Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ); Max Planck Society; Friedrich Schiller University of Jena
摘要:Structural color is an optical phenomenon resulting from light interacting with nanostructured materials. Although structural color (SC) is widespread in the tree of life, the underlying genetics and genomics are not well understood. Here, we collected and sequenced a set of 87 structurally colored bacterial isolates and 30 related strains lacking SC. Optical analysis of colonies indicated that diverse bacteria from at least two different phyla ( Bacteroidetes and Proteobacteria) ) can create ...
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作者:Denny, Sean; Englander, Gabriel; Hunnicutt, Patrick
作者单位:University of California System; University of California Santa Barbara; The World Bank; Chapman University System; Chapman University; University of Oregon
摘要:Protected areas can conserve wildlife and benefit people when managed effectively. African governments increasingly delegate the management of protected areas to private, nongovernmental organizations, hoping that private organizations' significant resources and technical capacities actualize protected areas' potential. Does private sector management improve outcomes compared to a counterfactual of government management? We leverage the transfer of management authority from governments to Afri...
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作者:Lin, Yu- Wei; Yang, Shiyu; Han, Wencui; Lu, Jackson G.
作者单位:Santa Clara University; California State University System; San Francisco State University; State University of New York (SUNY) System; Stony Brook University; Massachusetts Institute of Technology (MIT)
摘要:Watching movies is among the most popular entertainment and cultural activities. How do viewers react when a movie sequel increases racial minority actors in the main cast (minority increase)? On the one hand, such sequels may receive better evaluations if viewers appreciate racially inclusive casting for its novel elements (the value- in-- diversity perspective) and moral appeal (the fairness perspective on diversity). On the other hand, discrimination research suggests that if viewers harbor...
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作者:Driver, Justin G.; Bernard, Ellina; Patrizio, Piera; Fennell, Paul S.; Scrivener, Karen; Myers, Rupert J.
作者单位:Imperial College London; Imperial College London; Swiss Federal Institutes of Technology Domain; Swiss Federal Laboratories for Materials Science & Technology (EMPA); Imperial College London; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne
摘要:CO2 2 mineralization products are often heralded as having outstanding potentials to reduce CO2- eq. 2- eq. emissions. However, these claims are generally undermined by incomplete consideration of the life cycle climate change impacts, material properties, supply and demand constraints, and economic viability of CO2 2 mineralization products. We investigate these factors in detail for ten concrete-- related CO2 2 mineralization products to quantify their individual and global CO2- eq. 2- eq. e...
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作者:Bensel, Brandon M.; Previs, Samantha Beck; Bookwalter, Carol; Trybus, Kathleen M.; Walcott, Sam; Warshaw, David M.
作者单位:University of Vermont; Worcester Polytechnic Institute
摘要:Kinesin-1 ensembles maneuver vesicular cargoes through the three-dimensional (3D) intracellular microtubule (MT) network. To define how such cargoes navigate MT intersections, we first determined how many kinesins from an ensemble on a lipid-based cargo simultaneously engage a MT, and then determined the directional outcomes (straight, turn, terminate) for liposome cargoes at perpendicular MT intersections. Run lengths of 350-nm diameter liposomes decorated with up to 20, constitutively active...
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作者:Manna, Liberato; Odom, Teri W.
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作者:Zukowski, Stanislaw; Cornelissen, Annemiek Johanna Maria; Osselin, Florian; Douady, Stephane; Szymczak, Piotr
作者单位:University of Warsaw; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute for Engineering & Systems Sciences (INSIS); Universite Paris Cite; Universite Paris Cite; Bureau de Recherches Geologiques et Minieres (BRGM); Centre National de la Recherche Scientifique (CNRS); Universite de Orleans; CNRS - National Institute for Earth Sciences & Astronomy (INSU); Bureau de Recherches Geologiques et Minieres (BRGM); Universite de Orleans; Universite de Orleans
摘要:Transport networks, such as vasculature or river networks, provide key functions in organisms and the environment. They usually contain loops whose significance for the stability and robustness of the network is well documented. However, the dynamics of their formation is usually not considered. Such structures often grow in response to the gradient of an external field. During evolution, extending branches compete for the available flux of the field, which leads to effective repulsion between...
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作者:Bayones, Lucas; Zainos, Antonio; Alvarez, Manuel; Romo, Ranulfo; Franci, Alessio; Rossi-Poo, Roman
作者单位:Universidad Nacional Autonoma de Mexico; Universidad Nacional Autonoma de Mexico; University of Liege; Universidad Nacional Autonoma de Mexico
摘要:How does the brain simultaneously process signals that bring complementary information, like raw sensory signals and their transformed counterparts, without any disruptive interference? Contemporary research underscores the brain's adeptness in using decorrelated responses to reduce such interference. Both neurophysiological findings and artificial neural networks support the notion of orthogonal representation for signal differentiation and parallel processing. Yet, where, and how raw sensory...
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作者:Melogno, Isaty; Takatani, Shogo; Llanos, Paula; Goncalves, Coralie; Kodera, Chie; Martin, Marjolaine; Lionnet, Claire; Uyttewaal, Magalie; Pastuglia, Martine; Trehin, Christophe; Bouchez, David; Dumais, Jacques; Hamant, Olivier
作者单位:INRAE; Centre National de la Recherche Scientifique (CNRS); Ecole Normale Superieure de Lyon (ENS de LYON); Universite Claude Bernard Lyon 1; Nagoya University; Universidad Adolfo Ibanez; Universite Paris Saclay; INRAE; AgroParisTech
摘要:Although the formation of new walls during plant cell division tends to follow maximal tensile stress direction, analyses of individual cells over time reveal a much more variable behavior. The origin of such variability as well as the exact role of interphasic micro- tubule behavior before cell division have remained mysterious so far. To approach this question, we took advantage of the Arabidopsis stem, where the tensile stress pattern is both highly anisotropic and stable. Although cortical...