2024

最新文章

• Identifying outbreaks in sewer networks: An adaptive sampling scheme under network's uncertainty AI翻译
  作者：Baboun, Jose; Beaudry, Isabelle S.; Castro, Luis M.; Gutierrez, Felipe; Jara, Alejandro; Rubioa, Benjamin; Verschaea, Jose
  作者单位：Pontificia Universidad Catolica de Chile; Pontificia Universidad Catolica de Chile; Mount Holyoke College; Pontificia Universidad Catolica de Chile; Pontificia Universidad Catolica de Chile; Pontificia Universidad Catolica de Chile
  摘要：Motivated by the implementation of a SARS-Cov-2 sewer surveillance system in Chile during the COVID-19 pandemic, we propose a set of mathematical and algorithmic tools that aim to identify the location of an outbreak under uncertainty in the network structure. Given an upper bound on the number of samples we can take on any given day, our framework allows us to detect an unknown infected node by adaptively sampling different network nodes on different days. Crucially, despite the uncertainty o...
• Multiple forces facilitate the aquatic acrobatics of grasshopper and bioinspired robot AI翻译
  作者：Song, Yi; Wang, Huan; Dai, Zhendong; Ji, Aihong; Wu, Huaping; Gorb, Stanislav N.
  作者单位：Zhejiang University of Technology; Nanjing University of Aeronautics & Astronautics; University of Kiel; Southeast University - China
  摘要：Aquatic locomotion is challenging for land-dwelling creatures because of the high degree of fluidity with which the water yields to loads. We surprisingly found that the Chinese rice grasshopper Oxya chinensis, known for its terrestrial acrobatics, could swiftly launch itself off the water's surface in around 25 ms and seamlessly transition into flight. Biological observations showed that jumping grasshoppers use their front and middle legs to tilt up bodies first and then lift off by propelli...
• Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport AI翻译
  作者：Boytsov, Danila; Madej, Gregor M.; Horn, Georg; Blaha, Nadine; Koecher, Thomas; Sitte, Harald H.; Siekhaus, Daria; Ziegler, Christine; Sandtner, Walter; Roblek, Marko
  作者单位：University of California System; University of California Los Angeles; Medical University of Vienna; University of Regensburg; Vienna Biocenter (VBC); Al-Ahliyya Amman University; Medical University of Vienna; Institute of Science & Technology - Austria
  摘要：Orphan solute carrier (SLC) represents a group of membrane transporters whose exact functions and substrate specificities are not known. Elucidating the function and regulation of orphan SLC transporters is not only crucial for advancing our knowledge of cellular and molecular biology but can potentially lead to the development of new therapeutic strategies. Here, we provide evidence for the biological function of a ubiquitous orphan lysosomal SLC, the Major Facilitator Superfamily Domain- con...
• The evolutionary genomics of adaptation to stress in wild rhizobium bacteria AI翻译
  作者：Delgado, Hanna Kehlet -; Montoya, Angeliqua P.; Jensen, Kyson T.; Wendlandt, Camille E.; Dexheimer, Christopher; Roberts, Miles; Martinez, Lorena Torres; Friesen, Maren L.; Griffitts, Joel S.; Porter, Stephanie S.
  作者单位：Washington State University; Washington State University; Brigham Young University; St. Marys College of Maryland; Washington State University
  摘要：Microbiota comprise the bulk of life's diversity, yet we know little about how populations of microbes accumulate adaptive diversity across natural landscapes. Adaptation to stressful soil conditions in plants provides seminal examples of adaptation in response to natural selection via allelic substitution. For microbes symbiotic with plants however, horizontal gene transfer allows for adaptation via gene gain and loss, which could generate fundamentally different evolutionary dynamics. We use...
• Positive effects of public breeding on US rice yields under future climate scenarios AI翻译
  作者：Wang, Diane R.; Jamshidi, Sajad; Han, Rongkui; Edwards, Jeremy D.; Mcclung, Anna M.; Mccouch, Susan R.
  作者单位：Purdue University System; Purdue University; University of California System; University of California Davis; United States Department of Agriculture (USDA); Cornell University; Bayer AG; Bayer CropScience
  摘要：In this study, we model and predict rice yields by integrating molecular marker variation, varietal productivity, and climate, focusing on the Southern U.S. ricegrowing region. This region spans the states of Arkansas, Louisiana, Texas, Mississippi, and Missouri and accounts for 85% of total U.S. rice production. By digitizing and combining four decades of county -level variety acreage data (1970 to 2015) with varietal information from genotyping-by-sequencing data, we estimate annual historic...
• Climate change is poised to alter mountain stream ecosystem processes via organismal phenological shifts AI翻译
  作者：Leathers, Kyle; Herbst, David; de Mendoza, Guillermo; Doerschlag, Gabriella; Ruhi, Albert
  作者单位：University of California System; University of California Berkeley; University of California System; University of California Santa Barbara
  摘要：Climate change is affecting the phenology of organisms and ecosystem processes across a wide range of environments. However, the links between organismal and ecosystem process change in complex communities remain uncertain. In snow- dominated watersheds, snowmelt in the spring and early summer, followed by a long low- flow period, characterizes the natural flow regime of streams and rivers. Here, we examined how earlier snowmelt will alter the phenology of mountain stream organisms and ecosyst...
• The Arabidopsis BUB1/MAD3 family protein BMF3 requires BUB3.3 to recruit CDC20 to kinetochores in spindle assembly checkpoint signaling AI翻译
  作者：Deng, Xingguang; Peng, Felicia Lei; Tang, Xiaoya; Lee, Yuh-Ru Julie; Lin, Hong-Hui; Liu, Bo
  作者单位：Sichuan University; University of California System; University of California Davis; University of Pennsylvania
  摘要：The spindle assembly checkpoint (SAC) ensures faithful chromosome segregation during cell division by monitoring kinetochore- microtubule attachment. Plants produce both sequence- conserved and diverged SAC components, and it has been largely unknown how SAC activation leads to the assembly of these proteins at unattached kinetochores to prevent cells from entering anaphase. In Arabidopsis thaliana, the noncanonical BUB3.3 protein was detected at kinetochores throughout mitosis, unlike MAD1 an...
• Large nonlinear optical magnetoelectric response in a noncentrosymmetric magnetic Weyl semimetal AI翻译
  作者：Shoriki, Kentaro; Moriishi, Keigo; Okamura, Yoshihiro; Yokoi, Kohei; Usui, Hidetomo; Murakawa, Hiroshi; Sakai, Hideaki; Hanasaki, Noriaki; Tokura, Yoshinori; Takahashi, Youtarou
  作者单位：University of Tokyo; University of Tokyo; Gakushuin University; Shimane University; University of Osaka; RIKEN; University of Tokyo
  摘要：Weyl semimetals resulting from either inversion (P) or time- reversal (T) symmetry breaking have been revealed to show the record- breaking large optical response due to intense Berry curvature of Weyl-node pairs. Different classes of Weyl semimetals with both P and T symmetry breaking potentially exhibit optical magnetoelectric (ME) responses, which are essentially distinct from the previously observed optical responses in conventional Weyl semimetals, leading to the versatile functions such ...
• OSGN-1 is a conserved flavin- containing monooxygenase required to stabilize the intercellular bridge in late cytokinesis AI翻译
  作者：Goupil, Eugenie; Lacroix, Lea; Briere, Jonathan; Guga, Sandra; Saba-El-Leila, Marc K.; Melochea, Sylvain; Labbe, Jean-Claude
  作者单位：Universite de Montreal; Universite de Montreal; Universite de Montreal
  摘要：Cytokinesis is the last step of cell division and is regulated by the small GTPase RhoA. RhoA activity is required for all steps of cytokinesis, including prior to abscission when daughter cells are ultimately physically separated. Like germ cells in all animals, the Caenorhabditis elegans embryonic germline founder cell initiates cytokinesis but does not complete abscission, leaving a stable intercellular bridge between the two daughter cells. Here, we identify and characterize C. elegans OSG...
• The structure of PSI- LHCI from Cyanidium caldarium provides evolutionary insights into conservation and diversity of red- lineage LHCs AI翻译
  作者：Kato, Koji; Hamaguchi, Tasuku; Kumazawa, Minoru; Nakajima, Yoshiki; Ifuku, Kentaro; Hirooka, Shunsuke; Hirose, Yuu; Miyagishima, Shin-ya; Suzuki, Takehiro; Kawakami, Keisuke; Dohmae, Naoshi; Yonekura, Koji; Shen, Jian- Ren; Nagao, Ryo
  作者单位：Okayama University; Okayama University; Tohoku University; RIKEN; Kyoto University; Research Organization of Information & Systems (ROIS); National Institute of Genetics (NIG) - Japan; Toyohashi University of Technology; Graduate University for Advanced Studies - Japan; RIKEN; Shizuoka University
  摘要：Light- harvesting complexes (LHCs) are diversified among photosynthetic organisms, and the structure of the photosystem I-LHC (PSI-LHCI) supercomplex has been shown to be variable depending on the species of organisms. However, the structural and evolutionary correlations of red- lineage LHCs are unknown. Here, we determined a 1.92- & Aring; resolution cryoelectron microscopic structure of a PSI-LHCI supercomplex isolated from the red alga Cyanidium caldarium RK - 1 (NIES- 2137), which is an i...