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作者：Agarwal, Akshay; Kasaei, Leila; He, Xinglin; Kitichotkul, Ruangrawee; Hitit, Oguz Kagan; Peng, Minxu; Schultz, J. Albert; Feldman, Leonard C.; Goyal, Vivek K.
作者单位：Boston University; Rutgers University System; Rutgers University New Brunswick
摘要：Modern science is dependent on imaging on the nanoscale, often achieved through processes that detect secondary electrons created by a highly focused incident charged particle beam. Multiple types of measurement noise limit the ultimate trade-off between the image quality and the incident particle dose, which can preclude useful imaging of dose-sensitive samples. Existing methods to improve image quality do not fundamentally mitigate the noise sources. Furthermore, barriers to assigning a phys...
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作者：McDermott, Amy
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作者：Shah, Osama Shiraz; Nasrazadani, Azadeh; Foldi, Julia; Atkinson, Jennifer M.; Kleer, Celina G.; McAuliffe, Priscilla F.; Johnston, Tyler J.; Stallaert, Wayne; da Silva, Edaise M.; Selenica, Pier; Dopeso, Higinio; Pareja, Fresia; Mandelker, Diana; Weigelt, Britta; Reis-Filho, Jorge S.; Bhargava, Rohit; Lucas, Peter C.; Lee, Adrian V.; Oesterreich, Steffi
作者单位：Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Magee-Womens Research Institute; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Memorial Sloan Kettering Cancer Center; Mayo Clinic
摘要：Mixed invasive ductal and lobular carcinoma (MDLC) is a rare histologic subtype of breast cancer displaying both E-cadherin positive ductal and E-cadherin negative lobular morphologies within the same tumor, posing challenges with regard to anticipated clinical management. It remains unclear whether these distinct morphologies also have distinct biology and risk of recurrence. Our spatially resolved transcriptomic, genomic, and single- cell profiling revealed clinically significant differences...
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作者：Chawla, Aashna; Kumar, Deepak
作者单位：Indian Institute of Technology System (IIT System); Indian Institute of Technology (IIT) - Delhi
摘要：Soft and biological matter come in a variety of shapes and geometries. When soft surfaces that do not fit into each other due to a mismatch in Gaussian curvatures form an interface, beautiful geometry-induced patterns are known to emerge. In this paper, we study the effect of geometry on the dynamical response of soft surfaces moving relative to each other. Using a simple experimental scheme, we measure friction between a highly bendable thin polymer sheet and a hydrogel substrate. At this sof...
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作者：Garg, Akash; Yang, Feimo; Ozdoganlar, O. Burak; LeDuc, Philip R.
作者单位：Carnegie Mellon University; Carnegie Mellon University; Carnegie Mellon University; Carnegie Mellon University; Carnegie Mellon University; Carnegie Mellon University
摘要：Ice is emerging as a promising sacrificial material in the rapidly expanding area of advanced manufacturing for creating precise 3D internal geometries. Freeform 3D printing of ice (3D-ICE) can produce microscale ice structures with smooth walls, hierarchical transitions, and curved and overhang features. However, controlling 3D-ICE is challenging due to an incomplete understanding of its complex physics involving heat transfer, fluid dynamics, and phase changes. This work aims to advance our ...
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作者：Madeira, Lucas; Garcia-Orozco, ArnolD.; Moreno-Armijos, Michelle A.; Fritsch, Amilson R.; Bagnato, Vanderlei S.
作者单位：Universidade de Sao Paulo; Texas A&M University System; Texas A&M University College Station; Texas A&M University System; Texas A&M University College Station
摘要：Recent progress in out-of-equilibrium closed quantum systems has significantly advanced the understanding of mechanisms behind their evolution toward thermalization. Notably, the concept of nonthermal fixed points (NTFPs)-responsible for the emergence of spatiotemporal universal scaling in far-from-equilibrium systems- has played a crucial role in both theoretical and experimental investigations. In this work, we introduce a differential equation that has the universal scaling associated with ...
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作者：Lettermanna, Leon; Zieberta, Falko; Schwarz, Ulrich S.
作者单位：Ruprecht Karls University Heidelberg; Ruprecht Karls University Heidelberg
摘要：Gliding motility proceeds with little changes in cell shape and often results from actively driven surface flows of adhesins binding to the extracellular environment. It allows for fast movement over surfaces or through tissue, especially for the eukaryotic parasites from the phylum apicomplexa, which includes the causative agents of the widespread diseases malaria and toxoplasmosis. We have developed a fully three-dimensional active particle theory which connects the self-organized, actively ...
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作者：McDonald, Gavin; Bone, Jennifer; Costello, Christopher; Englander, Gabriel; Raynor, Jennifer
作者单位：University of California System; University of California Santa Barbara; University of California System; University of California Santa Barbara; University of California System; University of California Santa Barbara; The World Bank; University of Wisconsin System; University of Wisconsin Madison
摘要：The expansion of marine protected areas (MPAs) is a core focus of global conservation efforts, with the 30x30 initiative to protect 30% of the ocean by 2030 serving as a prominent example of this trend. We consider a series of proposed MPA network expansions of various sizes, and we forecast the impact this increase in protection would have on global patterns of fishing effort. We do so by building a predictive machine learning model trained on a global dataset of satellite-based fishing vesse...
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作者：Gewurz, Benjamin E.; Mosialos, George; Rickinson, Alan B.; Swaminathan, Sankar
作者单位：Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Aristotle University of Thessaloniki; University of Birmingham; Utah System of Higher Education; University of Utah
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作者：Zhang, Deyi; Shao, Yi; Zhou, Jiayi; Zhan, Qiangwei; Wen, Ziyang; Mao, Sheng; Wei, Jingjing; Qi, Limin; Shao, Yuanhua; Wang, Huan
作者单位：Peking University; Peking University; Shandong University
摘要：Liquid- phase electron microscopy (LP- EM) imaging has revolutionized our understanding sion that requires only standard microscopes. Depending on the imaging condition, the open geometry of the nanopipette allows the imaging of evaporation- induced pattern formation, but it can also function as an ordinary closed- geometry liquid cell where evaporation is negligible despite the nano opening. The nano coffee- ring phenomenon was observed by tracking individual nanoparticles in an evaporating n...
