3期

最新文章

• Soil microbiome bacteria protect plants against filamentous fungal infections via intercellular contacts AI翻译
  作者：Lin, Long; Shen, Danyu; Shao, Xiaolong; Yang, Yicheng; Li, Li; Zhong, Caihong; Jiang, Jiandong; Wang, Mengcen; Qian, Guoliang
  作者单位：Nanjing Agricultural University; Chinese Academy of Sciences; Wuhan Botanical Garden, CAS; Nanjing Agricultural University; Zhejiang University; Zhejiang University
  摘要：Bacterial-fungal interaction (BFI) has significant implications for the health of host plants. While the diffusible antibiotic metabolite- mediated competition in BFI has been extensively characterized, the impact of intercellular contact remains largely elusive. Here, we demonstrate that the intercellular contact is a prevalent mode of interaction between beneficial soil bacteria and pathogenic filamentous fungi. By generating antibiotics- deficient mutants in two common soil bacteria, Lysoba...
• Discrepancies between subjective and objective sleep assessments revealed by in- home electroencephalography during real- world sleep AI翻译
  作者：Masaki, Minori; Tsumoto, Saki; Tani, Akihiro; Tominaga, Morie; Seol, Jaehoon; Chiba, Shigeru; Miyanishi, Kazuya; Nishida, Kei; Kawana, Fusae; Amemiya, Takashi; Hiei, Tetsuro; Kanbayashi, Takashi; Yanagisawa, Masashi
  作者单位：University of Tsukuba; University of Tsukuba; University of Tsukuba; National Center for Geriatrics & Gerontology; Tokyo Metropolitan Institute of Gerontology
  摘要：Sleep insufficiency and sleep disorders pose serious health challenges. This study aimed to determine the potential discrepancy between subjective and objective sleep assessments, including the latter made by physicians, by analyzing a 421- participant dataset in Japan comprising multiple nights of in- home sleep electroencephalogram (EEG) data and questionnaire responses on sleep habits or subjective experiences. We employed logistic regression models to examine which subjective and objective...
• A divergent two- domain structure of the anti- Müllerian hormone prodomain AI翻译
  作者：Howard, James A.; Hok, Lucija; Cate, Richard L.; Sanford, Nathaniel J.; Hart, Kaitlin N.; Leach, Edmund A. E.; Bruening, Alena S.; Nagykery, Nicholas; Donahoe, Patricia K.; Thompson, Thomas B.
  作者单位：University System of Ohio; University of Cincinnati; University System of Ohio; University of Cincinnati; Boston University; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital
  摘要：TGFf3 family ligands are synthesized as precursors consisting of an N- terminal prodomain and C- terminal growth factor (GF) signaling domain. After proteolytic processing, the prodomain typically remains noncovalently associated with the GF, sometimes forming a high- affinity latent procomplex that requires activation. For the TGFf3 family ligand anti- M & uuml;llerian hormone (AMH), the prodomain maintains a high- affinity interaction with its GF that does not render it latent. While the pro...
• State shifts in the deep Critical Zone drive landscape evolution in volcanic terrains AI翻译
  作者：Karlstrom, Leif; Klema, Nathaniel; Grant, Gordon E.; Finn, Carol; Sullivan, Pamela L.; Cooley, Sarah; Simpson, Alex; Fasth, Becky; Cashman, Katharine; Ferrier, Ken; Ball, Lyndsay; Mckay, Daniele
  作者单位：University of Oregon; Fort Lewis College; United States Department of Agriculture (USDA); United States Forest Service; Oregon State University; United States Department of the Interior; United States Geological Survey; Duke University; University of Oregon; University of Wisconsin System; University of Wisconsin Madison
  摘要：Volcanic provinces are among the most active but least well understood landscapes on Earth. Here, we show that the central Cascade arc, USA, exhibits systematic spatial covariation of topography and hydrology that are linked to aging volcanic bedrock, suggesting systematic controls on landscape evolution. At the Cascade crest, a locus of Quaternary volcanism, water circulates deeply through the upper similar to 1 km of crust but transitions to shallow and dominantly horizontal flow as rocks ag...
• Tuning the electronic structure and SMSI by integrating trimetallic sites with defective ceria for the CO2 reduction reaction AI翻译
  作者：Singhvi, Charvi; Sharma, Gunjan; Verma, Rishi; Paidi, Vinod K.; Glatzel, Pieter; Paciok, Paul; Patel, Vashishtha B.; Mohan, Ojus; Polshettiwar, Vivek
  作者单位：Tata Institute of Fundamental Research (TIFR); European Synchrotron Radiation Facility (ESRF); Helmholtz Association; Research Center Julich; Indian Institute of Technology System (IIT System); Indian Institute of Technology (IIT) - Bombay
  摘要：Heterogeneous catalysts have emerged as a potential key for closing the carbon cycle by converting carbon dioxide (CO2) into value- added chemicals. In this work, we report a highly active and stable ceria (CeO2)-based electronically tuned trimetallic catalyst for CO2 to CO conversion. A unique distribution of electron density between the defective ceria support and the trimetallic nanoparticles (of Ni, Cu, Zn) was established by creating the strong metal support interaction (SMSI) between the...
• The Aedes aegypti mosquito evolves two types of prophenoloxidases with diversified functions AI翻译
  作者：Zhu, Xiaojing; Zhang, Lei; Jiang, Linlong; Chen, Huaqing; Tang, Yu; Yang, Xiaoyun; Bao, Pengkun; Liao, Chenghong; Li, Jianyong; Vavricka, Christopher J.; Ren, Delin; Chen, Zhaohui; Guo, Yingying; Han, Qian
  作者单位：Hainan University; Hainan University; Hainan Vocational University of Science & Technology; Virginia Polytechnic Institute & State University; Tokyo University of Agriculture & Technology
  摘要：Insect phenoloxidase, presented as an inactive precursor prophenoloxidase (PPO) in hemolymph, catalyzes melanin formation, which is involved in wound healing, pathogen killing, reversible oxygen collection during insect respiration, and cuticle and eggshell formation. Mosquitoes possess 9 to 16 PPO members across different genera, a number that is more than that found in other dipteran insects. However, the reasons for the redundancy of these PPOs and whether they have distinct biochemical pro...
• Random noise promotes slow heterogeneous synaptic dynamics important for robust working memory computation AI翻译
  作者：Rungratsameetaweemana, Nuttida; Kim, Robert; Chotibut, Thiparat; Sejnowski, Terrence J.
  作者单位：Columbia University; Salk Institute; Cedars Sinai Medical Center; Chulalongkorn University; University of California System; University of California San Diego; University of California System; University of California San Diego
  摘要：Recurrent neural networks (RNNs) based on model neurons that communicate via continuous signals have been widely used to study how cortical neural circuits perform cognitive tasks. Training such networks to perform tasks that require information maintenance over a brief period (i.e., working memory tasks) remains a challenge. Inspired by the robust information maintenance observed in higher cortical areas such as the prefrontal cortex, despite substantial inherent noise, we investigated the ef...
• A distributed subcortical circuit linked to instrumental information- seeking about threat AI翻译
  作者：Trier, Hailey A.; Khalighinejad, Nima; Hamilton, Sorcha; Harbison, Caroline; Priestley, Luke; Laubach, Mark; Klein-Fluegge, Miriam; Scholl, Jacqueline; Rushworth, Matthew F. S.
  作者单位：University of Oxford; American University; University of Oxford; Universite Claude Bernard Lyon 1; Centre National de la Recherche Scientifique (CNRS); Institut National de la Sante et de la Recherche Medicale (Inserm); University of Oxford
  摘要：Daily life for humans and other animals requires switching between periods of threatand reward- oriented behavior. We investigated neural activity associated with spontaneous switching, in a naturalistic task, between foraging for rewards and seeking information about potential threats with 7T fMRI in healthy humans. Switching was driven by estimates of likelihood of threat and reward. Both tracking of threat and switching to a vigilant mode in which people sought more information about potent...
• Starch- rich plant foods 780,000 y ago: Evidence from Acheulian percussive stone tools AI翻译
  作者：Ahituv, Hadar; Henry, Amanda G.; Melamed, Yoel; Inbar, Naama Goren-; Bakels, Corrie; Shumilovskikh, Lyudmila; Cabanes, Dan; Stone, Jeffery R.; Rowe, Walter F.; Alperson-Afil, Nira
  作者单位：Bar Ilan University; University of Haifa; Leiden University - Excl LUMC; Leiden University; Naturalis Biodiversity Center; Bar Ilan University; Bar Ilan University; Hebrew University of Jerusalem; University of Gottingen; Rutgers University System; Rutgers University New Brunswick; Indiana State University; George Washington University
  摘要：In contrast to animal foods, wild plants often require long, multistep processing techniques that involve significant cognitive skills and advanced toolkits to perform. These costs are thought to have hindered how hominins used these foods and delayed their adoption into our diets. Through the analysis of starch grains preserved on basalt anvils and percussors, we demonstrate that a wide variety of plants were processed by Middle Pleistocene hominins at the site of Gesher Benot Ya'aqov in Isra...
• The chromatin remodeler ADNP regulates neurodevelopmental disorder risk genes and neocortical neurogenesis AI翻译
  作者：Clemot-Dupont, Samuel; Fernandes, Jose Alex Lourenco; Larrigan, Sarah; Sun, Xiaoqi; Medisetti, Suma; Stanley, Rory; El Hankouri, Ziyad; Joshi, Shrilaxmi V.; Picketts, David J.; Shekhar, Karthik; Mattar, Pierre
  作者单位：University of Ottawa; Ottawa Hospital Research Institute; University of Ottawa; University of California System; University of California Berkeley; University of California System; University of California Berkeley; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; Massachusetts Institute of Technology (MIT)
  摘要：Although chromatin remodelers are among the most important risk genes associated with neurodevelopmental disorders (NDDs), the roles of these complexes during brain development are in many cases unclear. Here, we focused on the recently discovered ChAHP chromatin remodeling complex. The zinc finger and homeodomain transcription factor ADNP is a core subunit of this complex, and de novo ADNP mutations lead to intellectual disability and autism spectrum disorder. However, germline Adnp knockout ...