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• Floodplain forests drive fruit- eating fish diversity at the Amazon Basin-scale AI翻译
  作者：[Anonymous]
  摘要：Unlike most rivers globally, nearly all lowland Amazonian rivers have unregulated flow, supporting seasonally flooded floodplain forests. Floodplain forests harbor a unique tree species assemblage adapted to flooding and specialized fauna, including fruit-eating fish that migrate seasonally into floodplains, favoring expansive floodplain areas. Frugivorous fish are forest-dependent fauna critical to forest regeneration via seed dispersal and support commercial and artisanal fisheries. We imple...
• Correction for Gadea et al., The smallest electrochemical bubbles (121, e2406956121, 2024) AI翻译
  作者：Gadea, Esteban D.; Sirkin, Yamila A. Perez; Molinero, Valeria; Scherlis, Damian A.
• A histochemical approach to activity- based copper sensing reveals cuproplasia- dependent vulnerabilities in cancer AI翻译
  作者：Messina, Marco S.; Torrente, Laura; Pezacki, Aidan T.; Humpel, Hanna I.; Li, Erin L.; Miller, Sophia G.; Verdejo-Torres, Odette; Padilla-Benavides, Teresita; Brady, Donita C.; Killilea, David W.; Killilea, Alison N.; Ralle, Martina; Ward, Nathan P.; Ohata, Jun; Denicola, Gina M.; Chang, Christopher J.
  作者单位：University of Delaware; H Lee Moffitt Cancer Center & Research Institute; University of California System; University of California Berkeley; Princeton University; Oregon Health & Science University; Wesleyan University; University of Pennsylvania; University of Pennsylvania; University of California System; University of California San Francisco; University of California System; University of California Berkeley; North Carolina State University; University of California System; University of California Berkeley
  摘要：Copper is an essential nutrient for sustaining vital cellular processes spanning respiration, metabolism, and proliferation. However, loss of copper homeostasis, particularly misregulation of loosely bound copper ions which are defined as the labile copper pool, occurs in major diseases such as cancer, where tumor growth and metastasis have heightened requirement for this metal. To help decipher the role of copper in the etiology of cancer, we report a histochemical activity- based sensing app...
• Expansion of a conserved architecture drives the evolution of the primate visual cortex AI翻译
  作者：Meyer, Emily E.; Martynek, Marcelina; Kastner, Sabine; Livingstone, Margaret S.; Arcaro, Michael J.
  作者单位：University of Pennsylvania; University of Pennsylvania; Princeton University; Harvard University; Harvard Medical School
  摘要：Human brain evolution is marked by a disproportionate expansion of cortical regions associated with advanced perceptual and cognitive functions. While this expansion is often attributed to the emergence of novel specialized brain areas, modifications to evolutionarily conserved cortical regions also have been linked to species- specific behaviors. Distinguishing between these two evolutionary outcomes has been limited by the ability to make direct comparisons between species. Here, we addresse...
• Dual modes of DNA N6-methyladenine maintenance by distinct methyltransferase complexes AI翻译
  作者：Wang, Yuanyuan; Nan, Bei; Ye, Fei; Zhang, Zhe; Yang, Wentao; Pan, Bo; Wei, Fan; Duan, Lili; Li, Haicheng; Niu, Junhua; Ju, Aili; Liu, Yongqiang; Wang, Dantong; Zhang, Wenxin; Liu, Yifan; Gao, Shan
  作者单位：Ocean University of China; Ocean University of China; University of Southern California; Yunnan University
  摘要：Stable inheritance of DNA N6- methyladenine (6mA) is crucial for its biological functions in eukaryotes. Here, we identify two distinct methyltransferase (MTase) complexes, both sharing the catalytic subunit AMT1, but featuring AMT6 and AMT7 as their unique components, respectively. While the two complexes are jointly responsible for 6mA maintenance methylation, they exhibit distinct enzy-mology, DNA/chromatin affinity, genomic distribution, and knockout phenotypes. AMT7 complex, featuring hig...
• Decoding the elite soccer player's psychological profile AI翻译
  作者：Bonettia, Leonardo; Vestberge, Torbjorn; Jafarie, Reza; Seghezzid, Debora; Ingvare, Martin; Kringelbacha, Morten L.; Filgueiras, Alberto; Petrovic, Predrag
  作者单位：Aarhus University; University of Oxford; University of Oxford; University of Bologna; Karolinska Institutet; Karolinska Institutet; Central Queensland University; Universidade do Estado do Rio de Janeiro
  摘要：Soccer is arguably the most widely followed sport worldwide, and many dream of becoming soccer players. However, only a few manage to achieve this dream, which has cast a significant spotlight on elite soccer players who possess exceptional skills to rise above the rest. Originally, such attention was focused on their great physical abilities. However, recently, a new perspective has emerged, suggesting that being an elite soccer player requires a deep understanding of the game, rapid informat...
• Facet- switching of rate- determining step on copper in CO2-to- ethylene electroreduction (vol 121, e2400546121, 2024) AI翻译
  作者：Zhang, Yu-Cai; Zhang, Xiao-Long; Wu, Zhi-Zheng; Niu, Zhuang-Zhuang; Chi, Li-Ping; Gao, Fei-Yue; Yang, Peng-Peng; Wang, Ye-Hua; Yu, Peng-Cheng; Duanmu, Jing-Wen; Sun, Shu-Ping; Gao, Min-Rui
• Direct lysine dimethylation of IRF3 by the methyltransferase SMYD3 attenuates antiviral innate immunity AI翻译
  作者：Wang, Zixuan; Chen, Xiaoyun; Zhu, Chunchun; Fan, Sijia; Tang, Jinhua; Deng, Hongyan; Sun, Xueyi; Liu, Xing; Xiao, Wuhan
  作者单位：Chinese Academy of Sciences; Institute of Hydrobiology, CAS; Hubei Hongshan Laboratory; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Chinese Academy of Sciences
  摘要：Interferon regulatory factor 3 (IRF3) is the key transcription factor in the type I IFN signaling pathway, whose activation is regulated by multiple posttranslational modifica-tions. Here, we identify SMYD3, a lysine methyltransferase, as a negative regulator of IRF3. SMYD3 interacts with IRF3 and catalyzes the dimethylation of IRF3 at lysine 39. This modification reduces IRF3 phosphorylation, dimerization, and subsequent nuclear translocation, leading to the inhibition of downstream type I in...
• Floodplain forests drive fruit-eating fish diversity at the Amazon Basin-scale AI翻译
  作者：Correa, Sandra Bibiana; Coronado-Franco, Karold V.; Jezequel, Celine; Rodrigues, Amanda Cantarute; Evans, Kristine O.; Granger, Joshua J.; Ter Steege, Hans; do Amaral, Ieda Leao; Coelho, Luiz de Souza; Wittmann, Florian; de Almeida Matos, Francisca Dionizia; Lima Filho, Diogenes de Andrade; Salomao, Rafael P.; Castilho, Carolina V.; Guevara, Juan Ernesto; Veiga Carim, Marcelo de Jesus; Phillips, Oliver L.; Fernandez Piedade, Maria Teresa; Demarchi, Layon O.; Schongart, Jochen; Cardenas Revilla, Juan David; Martins, Maria Pires; Irume, Mariana Victoria; da Silva Guimaraes, Jose Renan; Ramos, Jose Ferreira; Quaresma, Adriano Costa; Pitman, Nigel C. A.; Luize, Bruno Garcia; Moraes de Leao Novo, Evlyn Marcia; Venticinque, Eduardo Martins; Freire Silva, Thiago Sanna; Nunez Vargas, Percy; Manzatto, Angelo Gilberto; Costa Reis, Neidiane Farias; Terborgh, John; Casula, Katia Regina; Honorio Coronado, Euridice N.; Carlos Montero, Juan; Monteagudo Mendoza, Abel; Feldpausch, Ted R.; Durgante, Flavia Machado; Castano Arboleda, Nicolas; Marimon, Beatriz S.; Marimon-Junior, Ben Hur; Killeen, Timothy J.; Vasquez, Rodolfo; Mostacedo, Bonifacio; Assis, Rafael L.; do Amaral, Dario Dantas; Householder, John Ethan; Simon, Marcelo Fragomeni; de Medeiros, Marcelo Brilhante; de Queiroz, Helder Lima; Lopes, Maria Aparecida; Lima Magalhaes, Jose Leonardo; Stevenson, Pablo R.; Ladvocat Cintra, Bruno Barcante; Araujo-Murakami, Alejandro; Baker, Tim R.; Feitosa, Yuri Oliveira; Mogollon, Hugo F.; Duivenvoorden, Joost F.; Ferreira, Leandro Valle; de Toledo, Jose Julio; Comiskey, James A.; Lopes, Aline; Damasco, Gabriel; Vicentini, Alberto; Cornejo Valverde, Fernando; Gomes, Vitor H. F.; Alonso, Alfonso; Dallmeier, Francisco; de Aguiar, Daniel P. P.; Gribel, Rogerio; Carlos Licona, Juan; Villa Zegarra, Boris Eduardo; Guedes, Marcelino Carneiro; Ceron, Carlos; Thomas, Raquel; Milliken, William; Campelo, Wegliane; Albuquerque, Bianca Weiss; Klitgaard, Bente; Tello, J. Sebastian; Fuentes Claros, Alfredo; Rivas-Torres, Gonzalo; Fernando Phillips, Juan; von Hildebrand, Patricio; Gonzales, Therany; Vela, Cesar I. A.; Hoffman, Bruce; Flores, Bernardo Monteiro; Pombo, Maihyra Marina; Rocha, Maira; Holmgren, Milena; Cano, Angela; Umana, Maria Natalia; Fernanda Casas, Luisa; Balslev, Henrik; Urrego Giraldo, Ligia Estela; Bigorne, Remy; Oberdorff, Thierry; Maldonado-Ocampo, Javier A.; Ortega, Hernan; Hidalgo, Max; Martens, Koen; Torrente-Vilara, Gislene; Zuanon, Jansen; Acosta, Astrid; Agudelo, Edwin; Barrera Maure, Soraya; Bastos, Douglas A.; Bogota Gregory, Juan; Cabeceira, Fernando G.; Canto, Andre L. C.; Carvajal-Vallejos, Fernando M.; Carvalho, Lucelia N.; Cella-Ribeiro, Ariana; Covain, Raphael; Dias, Murilo S.; Donascimiento, Carlos; Doria, Carolina R. C.; Duarte, Cleber; Ferreira, Efrem J. G.; Galuch, Andre V.; Giarrizzo, Tommaso; Leitao, Rafael P.; Lundberg, John G.; Maldonado, Mabel; Mojica, Jose I.; Montag, Luciano F. A.; Ohara, William; Pires, Tiago H. S.; Pouilly, Marc; Prada-Pedreros, Saul; de Queiroz, Luiz J.; Py-Daniel, Lucia Rapp; Ribeiro, Frank R. V.; Herrera, Raul Rios; dos Anjos, Marcelo Rodrigues; Lourenco, Igor Hister; Sarmiento, Jaime; Sousa, Leandro M.; Stegmann, Lis F.; Valdiviezo-Rivera, Jonathan; Villa, Francisco; Yunoki, Takayuki; Tedesco, Pablo A.
  作者单位：Mississippi State University; Universite de Toulouse; Universite Toulouse III - Paul Sabatier; Universite Federale Toulouse Midi-Pyrenees (ComUE); Institut National Polytechnique de Toulouse; Institut de Recherche pour le Developpement (IRD); Mississippi State University; Naturalis Biodiversity Center; Utrecht University; Institute Nacional de Pesquisas da Amazonia; Helmholtz Association; Karlsruhe Institute of Technology; Institute Nacional de Pesquisas da Amazonia; Universidade Federal Rural da Amazonia (UFRA); Museu Paraense Emilio Goeldi; Empresa Brasileira de Pesquisa Agropecuaria (EMBRAPA); EMBRAPA Roraima; Universidad de Las Americas - Ecuador; University of Leeds; Field Museum of Natural History (Chicago); Universidade Estadual de Campinas; Universidade de Sao Paulo; Instituto Nacional de Pesquisas Espaciais (INPE); Universidade Federal do Rio Grande do Norte; University of Stirling; Universidad Nacional de San Antonio Abad del Cusco; Universidade Federal de Rondonia; Universidade Federal de Rondonia; State University System of Florida; University of Florida; State University System of Florida; University of Florida; James Cook University; James Cook University; University of St Andrews; University of Exeter; Universidade do Estado de Mato Grosso; Instituto Tecnologico Vale Desenvolvimento Sustentavel; Empresa Brasileira de Pesquisa Agropecuaria (EMBRAPA); EMBRAPA Genetic Resources & Biotechnology; Universidade Federal do Para; Universidade Federal do Para; Empresa Brasileira de Pesquisa Agropecuaria (EMBRAPA); EMBRAPA Amazonia Oriental; Universidad de los Andes (Colombia); University of Birmingham; Institute Nacional de Pesquisas da Amazonia; University of Amsterdam; Fundacao Universidade Federal do Amapa; United States Department of the Interior; US National Park Service; Smithsonian Institution; Smithsonian National Zoological Park & Conservation Biology Institute; University of Gothenburg; Institute Nacional de Pesquisas da Amazonia; Centro Universitario do Estado do Para (CESUPA); Universidade Federal do Para; Institute Nacional de Pesquisas da Amazonia; Empresa Brasileira de Pesquisa Agropecuaria (EMBRAPA); Universidad Central del Ecuador; Royal Botanic Gardens, Kew; Royal Botanic Gardens, Kew; Missouri Botanical Gardens; Universidad Mayor de San Andres; Universidad San Francisco de Quito; State University System of Florida; University of Florida; Universidad Nacional de San Antonio Abad del Cusco; Universidade Federal de Santa Catarina (UFSC); Wageningen University & Research; University of Cambridge; University of Michigan System; University of Michigan; Aarhus University; Universidad Nacional de Colombia; Universidad Nacional Mayor de San Marcos; Royal Belgian Institute of Natural Sciences; Universidade Federal de Sao Paulo (UNIFESP); Universidade Santa Cecilia; Universidad Mayor de San Andres; La Coleccion Boliviana de Fauna; Universidade Federal de Mato Grosso; Universidade de Cuiaba; Universidade Federal do Oeste do Para; Universidad Mayor de San Simon; Universidade Federal de Mato Grosso; Universidade de Brasilia; Universidad de Antioquia; Universidade Federal de Rondonia; Universidade Federal do Para; Universidade Federal de Minas Gerais; Drexel University; Drexel University; Universidade Federal do Para; Universidade Federal de Rondonia; Museum National d'Histoire Naturelle (MNHN); Sorbonne Universite; Institut de Recherche pour le Developpement (IRD); Universite de Caen Normandie; Pontificia Universidad Javeriana; University of Groningen; Universidade Federal de Amazonas; Universidade Federal do Para; Universidad del Tolima
  摘要：Unlike most rivers globally, nearly all lowland Amazonian rivers have unregulated flow, supporting seasonally flooded floodplain forests. Floodplain forests harbor a unique tree species assemblage adapted to flooding and specialized fauna, including fruit-eating fish that migrate seasonally into floodplains, favoring expansive floodplain areas. Frugivorous fish are forest-dependent fauna critical to forest regeneration via seed dispersal and support commercial and artisanal fisheries. We imple...
• High- resolution national radon maps based on massive indoor measurements in the United States AI翻译
  作者：Li, Longxiang; Coull, Brent A.; Vieira, Carolina L. Zilli; Koutrakis, Petros
  作者单位：Harvard University; Harvard T.H. Chan School of Public Health; Emory University; Rollins School Public Health; Harvard University; Harvard T.H. Chan School of Public Health
  摘要：Radon, a common radioactive indoor air pollutant, is the second leading cause of lung cancer in the United States. Knowledge about its distribution is essential for risk assessment and designing efficient protective regulations. However, the three current radon maps for the United States are unable to provide the up- to- date, high- resolution, and time- varying radon concentrations. Tens of millions of radon measurements have been conducted as parts of property inspections in the past two dec...