-
作者:Larkin, James; Beland, Chloe; Ramalingam, Sivatharshini; Lyon, Alexander R.
作者单位:Royal Marsden NHS Foundation Trust; Royal Brompton Hospital
-
作者:Collins, Pamela Y.; Sinha, Moitreyee; Concepcion, Tessa; Patton, George; Way, Thaisa; McCay, Layla; Mensa-Kwao, Augustina; Herrman, Helen; de Leeuw, Evelyne; Anand, Nalini; Atwoli, Lukoye; Bardikoff, Nicole; Booysen, Chantelle; Bustamante, Ines; Chen, Yajun; Davis, Kelly; Dua, Tarun; Foote, Nathaniel; Hughsam, Matthew; Juma, Damian; Khanal, Shisir; Kumar, Manasi; Lefkowitz, Bina; McDermott, Peter; Moitra, Modhurima; Ochieng, Yvonne; Omigbodun, Olayinka; Queen, Emily; Unuetzer, Juergen; Uribe-Restrepo, Jose Miguel; Wolpert, Miranda; Zeitz, Lian
作者单位:Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health; University of Washington; University of Washington Seattle; University of Melbourne; Harvard University; Orygen, The National Centre of Excellence in Youth Mental Health; University of Melbourne; Universite de Montreal; National Institutes of Health (NIH) - USA; NIH Fogarty International Center (FIC); Aga Khan University; Universidad Peruana Cayetano Heredia; Sun Yat Sen University; World Health Organization; New York University; University of Nairobi; Duke University; University of Ibadan; Pontificia Universidad Javeriana
摘要:Urban life shapes the mental health of city dwellers, and although cities provide access to health, education and economic gain, urban environments are often detrimental to mental health(1,2). Increasing urbanization over the next three decades will be accompanied by a growing population of children and adolescents living in cities(3). Shaping the aspects of urban life that influence youth mental health could have an enormous impact on adolescent well-being and adult trajectories(4). We invite...
-
作者:Ngo, Linh H.; Bert, Andrew G.; Dredge, B. Kate; Williams, Tobias; Murphy, Vincent; Li, Wanqiu; Hamilton, William B.; Carey, Kirstyn T.; Toubia, John; Pillman, Katherine A.; Liu, Dawei; Desogus, Jessica; Chao, Jeffrey A.; Deans, Andrew J.; Goodall, Gregory J.; Wickramasinghe, Vihandha O.
作者单位:University of Melbourne; Peter Maccallum Cancer Center; University of Melbourne; Peter Maccallum Cancer Center; University of South Australia; Centre for Cancer Biology; SA Pathology; St. Vincent's Institute of Medical Research; Southern University of Science & Technology; Southern University of Science & Technology; University of Adelaide; Friedrich Miescher Institute for Biomedical Research; University of Basel; University of Adelaide; University of Melbourne; University of Adelaide; University of Adelaide; Friedrich Miescher Institute for Biomedical Research
摘要:Circular RNAs (circRNAs), which are increasingly being implicated in a variety of functions in normal and cancerous cells(1-5), are formed by back-splicing of precursor mRNAs in the nucleus(6-10). circRNAs are predominantly localized in the cytoplasm, indicating that they must be exported from the nucleus. Here we identify a pathway that is specific for the nuclear export of circular RNA. This pathway requires Ran-GTP, exportin-2 and IGF2BP1. Enhancing the nuclear Ran-GTP gradient by depletion...
-
作者:Knights, Antony; Lemasson, Anaelle; Frost, Matthew; Somerfield, Paul
作者单位:University College Cork; University of Plymouth; Plymouth Marine Laboratory; Plymouth Marine Laboratory
-
作者:Stenzinger, Albrecht; Klauschen, Frederick
作者单位:Ruprecht Karls University Heidelberg; University of Munich
-
作者:Stokowski, Hubert S.; Dean, Devin J.; Hwang, Alexander Y.; Park, Taewon; Celik, Oguz Tolga; McKenna, Timothy P.; Jankowski, Marc; Langrock, Carsten; Ansari, Vahid; Fejer, Martin M.; Safavi-Naeini, Amir H.
作者单位:Stanford University; Stanford University
摘要:Optical frequency combs have revolutionized precision measurement, time-keeping and molecular spectroscopy1-7. A substantial effort has developed around 'microcombs': integrating comb-generating technologies into compact photonic platforms5,7-9. Current approaches for generating these microcombs involve either the electro-optic10 or Kerr mechanisms11. Despite rapid progress, maintaining high efficiency and wide bandwidth remains challenging. Here we introduce a previously unknown class of micr...
-
作者:Ohenhen, Leonard O.; Shirzaei, Manoochehr; Ojha, Chandrakanta; Sherpa, Sonam F.; Nicholls, Robert J.
作者单位:Virginia Polytechnic Institute & State University; Virginia Polytechnic Institute & State University; Indian Institute of Science Education & Research (IISER) - Mohali; Brown University; Brown University; University of East Anglia
摘要:The sea level along the US coastlines is projected to rise by 0.25-0.3 m by 2050, increasing the probability of more destructive flooding and inundation in major cities1-3. However, these impacts may be exacerbated by coastal subsidence-the sinking of coastal land areas4-a factor that is often underrepresented in coastal-management policies and long-term urban planning2,5. In this study, we combine high-resolution vertical land motion (that is, raising or lowering of land) and elevation datase...
-
作者:Tao, Feng; Houlton, Benjamin Z.; Frey, Serita D.; Lehmann, Johannes; Manzoni, Stefano; Huang, Yuanyuan; Jiang, Lifen; Mishra, Umakant; Hungate, Bruce A.; Schmidt, Michael W. I.; Reichstein, Markus; Carvalhais, Nuno; Ciais, Philippe; Wang, Ying-Ping; Ahrens, Bernhard; Hugelius, Gustaf; Hocking, Toby D.; Lu, Xingjie; Shi, Zheng; Viatkin, Kostiantyn; Vargas, Ronald; Yigini, Yusuf; Omuto, Christian; Malik, Ashish A.; Peralta, Guillermo; Cuevas-Corona, Rosa; Di Paolo, Luciano E.; Luotto, Isabel; Liao, Cuijuan; Liang, Yi-Shuang; Saynes, Vinisa S.; Huang, Xiaomeng; Luo, Yiqi
作者单位:Cornell University; Tsinghua University; Cornell University; University System Of New Hampshire; University of New Hampshire; Cornell University; Stockholm University; Stockholm University; Chinese Academy of Sciences; Institute of Geographic Sciences & Natural Resources Research, CAS; United States Department of Energy (DOE); Sandia National Laboratories; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; Joint BioEnergy Institute - JBEI; Northern Arizona University; Northern Arizona University; University of Zurich; Max Planck Society; Universidade Nova de Lisboa; CEA; Universite Paris Saclay; Centre National de la Recherche Scientifique (CNRS); Commonwealth Scientific & Industrial Research Organisation (CSIRO); CSIRO Environment; Sun Yat Sen University; University of Oklahoma System; University of Oklahoma - Norman; University of Oklahoma System; University of Oklahoma - Norman; Food & Agriculture Organization of the United Nations (FAO); University of Aberdeen
-
作者:Castano, Victor M.; de Cordoba, Pedro Fernandez; Sans, Juan A.; Violini, Galileo
作者单位:Universidad Nacional Autonoma de Mexico; Universidad Nacional Autonoma de Mexico; Universitat Politecnica de Valencia; Universitat Politecnica de Valencia
摘要:An advanced light source for research would boost growth in the Greater Caribbean region - scientific, economic and societal.
-
作者:Reardon, Sara