-
作者：Drew, Liam
-
作者：Majander, Kerttu; Pla-Diaz, Marta; du Plessis, Louis; Arora, Natasha; Filippini, Jose; Pezo-Lanfranco, Luis; Eggers, Sabine; Gonzalez-Candelas, Fernando; Schuenemann, Verena J.
作者单位：University of Zurich; University of Vienna; University of Basel; Instituto de Salud Carlos III; CIBER - Centro de Investigacion Biomedica en Red; CIBERESP; Swiss Federal Institutes of Technology Domain; ETH Zurich; Swiss Institute of Bioinformatics; University of Zurich; Universidade de Sao Paulo; Autonomous University of Barcelona; Autonomous University of Barcelona; University of Vienna
摘要：The origins of treponemal diseases have long remained unknown, especially considering the sudden onset of the first syphilis epidemic in the late 15th century in Europe and its hypothesized arrival from the Americas with Columbus' expeditions(1,2). Recently, ancient DNA evidence has revealed various treponemal infections circulating in early modern Europe and colonial-era Mexico(3-6). However, there has been to our knowledge no genomic evidence of treponematosis recovered from either the Ameri...
-
作者：Bloxham, Jeremy; Cao, Hao; Stevenson, David J.; Connerney, John E. P.; Bolton, Scott J.
作者单位：Harvard University; University of California System; University of California Los Angeles; California Institute of Technology; National Aeronautics & Space Administration (NASA); NASA Goddard Space Flight Center; Southwest Research Institute
摘要：Planetary magnetic fields provide a window into the otherwise largely inaccessible dynamics of a planet's deep interior. In particular, interaction between fluid flow in electrically conducting interior regions and the magnetic field there gives rise to observable secular variation (time dependency) of the externally observed magnetic field. Secular variation of Jupiter's field has recently been revealed1-3 and been shown to arise, in part, from an axisymmetric, equatorial jet2. Whether this j...
-
作者：Bhattacharyya, P.; Chen, W.; Huang, X.; Chatterjee, S.; Huang, B.; Kobrin, B.; Lyu, Y.; Smart, T. J.; Block, M.; Wang, E.; Wang, Z.; Wu, W.; Hsieh, S.; Ma, H.; Mandyam, S.; Chen, B.; Davis, E.; Geballe, Z. M.; Zu, C.; Struzhkin, V.; Jeanloz, R.; Moore, J. E.; Cui, T.; Galli, G.; Halperin, B. I.; Laumann, C. R.; Yao, N. Y.
作者单位：University of California System; University of California Berkeley; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; Jilin University; Carnegie Mellon University; University of Chicago; University of California System; University of California Berkeley; Harvard University; Harvard University; Carnegie Institution for Science; Washington University (WUSTL); Ningbo University; United States Department of Energy (DOE); Argonne National Laboratory; United States Department of Energy (DOE); Argonne National Laboratory; University of Chicago; Boston University
摘要：By directly altering microscopic interactions, pressure provides a powerful tuning knob for the exploration of condensed phases and geophysical phenomena(1). The megabar regime represents an interesting frontier, in which recent discoveries include high-temperature superconductors, as well as structural and valence phase transitions(2-6). However, at such high pressures, many conventional measurement techniques fail. Here we demonstrate the ability to perform local magnetometry inside a diamon...
-
作者：Feng, Hanke; Ge, Tong; Guo, Xiaoqing; Wang, Benshan; Zhang, Yiwen; Chen, Zhaoxi; Zhu, Sha; Zhang, Ke; Sun, Wenzhao; Huang, Chaoran; Yuan, Yixuan; Wang, Cheng
作者单位：City University of Hong Kong; City University of Hong Kong; University of Oxford; Chinese University of Hong Kong; Beijing University of Technology; City University of Hong Kong (Dongguan); Shenzhen Research Institute, City University of Hong Kong; City University of Hong Kong
摘要：Integrated microwave photonics (MWP) is an intriguing technology for the generation, transmission and manipulation of microwave signals in chip-scale optical systems(1,2). In particular, ultrafast processing of analogue signals in the optical domain with high fidelity and low latency could enable a variety of applications such as MWP filters(3-5), microwave signal processing(6-9) and image recognition(10,11). An ideal integrated MWP processing platform should have both an efficient and high-sp...
-
作者：Ho, Kin On; Yang, Sen
作者单位：Centre National de la Recherche Scientifique (CNRS); Universite Paris Saclay; Hong Kong University of Science & Technology
摘要：By adapting a device designed to create extremely high pressures into one that can sense magnetic fields, researchers have obtained evidence that a hydrogen-rich material is a superconductor, eliminating long-standing doubts.
-
作者：Elemans, Coen P. H.; Jiang, Weili; Jensen, Mikkel H.; Pichler, Helena; Mussman, Bo R.; Nattestad, Jacob; Wahlberg, Magnus; Zheng, Xudong; Xue, Qian; Fitch, W. Tecumseh
作者单位：University of Southern Denmark; Rochester Institute of Technology; University of Vienna; University of Southern Denmark; Odense University Hospital; University of Southern Denmark; University of Vienna
摘要：Baleen whales (mysticetes) use vocalizations to mediate their complex social and reproductive behaviours in vast, opaque marine environments(1). Adapting to an obligate aquatic lifestyle demanded fundamental physiological changes to efficiently produce sound, including laryngeal specializations(2-4). Whereas toothed whales (odontocetes) evolved a nasal vocal organ(5), mysticetes have been thought to use the larynx for sound production(1,6-8). However, there has been no direct demonstration tha...
-
作者：Hsia, Oliver; Hinterndorfer, Matthias; Cowan, Angus D.; Iso, Kentaro; Ishida, Tasuku; Sundaramoorthy, Ramasubramanian; Nakasone, Mark A.; Imrichova, Hana; Schaetz, Caroline; Rukavina, Andrea; Husnjak, Koraljka; Wegner, Martin; Correa-Saez, Alejandro; Craigon, Conner; Casement, Ryan; Maniaci, Chiara; Testa, Andrea; Kaulich, Manuel; Dikic, Ivan; Winter, Georg E.; Ciulli, Alessio
作者单位：University of Dundee; Austrian Academy of Sciences; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences; Eisai Co Ltd; University of Dundee; Goethe University Frankfurt; University of Dundee
摘要：Targeted protein degradation is a pharmacological modality that is based on the induced proximity of an E3 ubiquitin ligase and a target protein to promote target ubiquitination and proteasomal degradation. This has been achieved either via proteolysis-targeting chimeras (PROTACs)-bifunctional compounds composed of two separate moieties that individually bind the target and E3 ligase, or via molecular glues that monovalently bind either the ligase or the target(1-4). Here, using orthogonal gen...
-
作者：Libonati, Renata
作者单位：Universidade Federal do Rio de Janeiro
摘要：It's not just global warming that's driving the growth in destructive wildfires. Better land management is the first step to mitigating the risks.
-
作者：Serini, Guido; Valdembri, Donatella; Zanivan, Sara; Morterra, Giulia; Burkhardt, Constanze; Caccavari, Francesca; Zammataro, Luca; Primo, Luca; Tamagnone, Luca; Logan, Malcolm; Tessier-Lavigne, Marc; Taniguchi, Masahiko; Pueschel, Andreas W.; Bussolino, Federico
作者单位：IRCCS Fondazione del Piemonte per l'Oncologia; University of Turin; University of Turin; University of Munster; IRCCS Fondazione del Piemonte per l'Oncologia; MRC National Institute for Medical Research; Stanford University; Howard Hughes Medical Institute; University of Tokyo
