2024

最新文章

• The cortical amygdala consolidates a socially transmitted long-term memory AI翻译
  作者：Liu, Zhihui; Sun, Wenfei; Ng, Yi Han; Dong, Hua; Quake, Stephen R.; Sudhof, Thomas C.
  作者单位：Stanford University; Howard Hughes Medical Institute; Stanford University; Stanford University; Stanford University; Chan Zuckerberg Initiative (CZI)
  摘要：Social communication guides decision-making, which is essential for survival. Social transmission of food preference (STFP) is an ecologically relevant memory paradigm in which an animal learns a desirable food odour from another animal in a social context, creating a long-term memory(1,2). How food-preference memory is acquired, consolidated and stored is unclear. Here we show that the posteromedial nucleus of the cortical amygdala (COApm) serves as a computational centre in long-term STFP me...
• Protein droplets spread to seal tight junctions AI翻译
  作者：Ludwig, Alexander
  作者单位：Nanyang Technological University; Nanyang Technological University
  摘要：Cells that form tissue barriers rely on cell-cell contacts called tight junctions. These structures assemble from protein condensates that spread along the cell membrane like a water droplet spreading over glass. Step-by-step formation of tight junctions between epithelial cells.
• HOW TO SPOT A PREDATORY CONFERENCE AI翻译
  作者：Ro, Christine
• Genetic links found to the world's biggest killer of new mothers AI翻译
  作者：[Anonymous]
  摘要：Genes associated with postpartum haemorrhage spotlight a hormone's role in dangerous bleeding after childbirth.
• Clonal inactivation of TERT impairs stem cell competition AI翻译
  作者：Hasegawa, Kazuteru; Zhao, Yang; Garbuzov, Alina; Corces, M. Ryan; Neuhofer, Patrick; Gillespie, Victoria M.; Cheung, Peggie; Belk, Julia A.; Huang, Yung-Hsin; Wei, Yuning; Chen, Lu; Chang, Howard Y.; Artandi, Steven E.
  作者单位：Stanford Cancer Institute; Stanford University; Stanford University; Stanford University; Fox Chase Cancer Center; Stanford University; Howard Hughes Medical Institute; Stanford University
  摘要：Telomerase is intimately associated with stem cells and cancer, because it catalytically elongates telomeres-nucleoprotein caps that protect chromosome ends(1). Overexpression of telomerase reverse transcriptase (TERT) enhances the proliferation of cells in a telomere-independent manner(2-8), but so far, loss-of-function studies have provided no evidence that TERT has a direct role in stem cell function. In many tissues, homeostasis is shaped by stem cell competition, a process in which stem c...
• Polar bear threat for Arctic researchers AI翻译
  作者：Strunk, Astrid
  作者单位：Lund University
  摘要：Letter to the Editor
• Supreme Court ruling alters risk landscape AI翻译
  作者：Trump, Benjamin D.; Linkov, Igor
  作者单位：United States Department of Defense; United States Army; U.S. Army Corps of Engineers; U.S. Army Engineer Research & Development Center (ERDC)
  摘要：Letter to the Editor
• How does the spliceosome dismantle itself? AI翻译
  作者：Shi, Shasha; Zhao, Rui
  作者单位：University of Colorado System; University of Colorado Anschutz Medical Campus
  摘要：Precursor messenger RNA is edited into its final form by an RNA-protein assembly called the spliceosome. Structural evidence provides insights into how the spliceosome is disassembled when its job is complete.
• Carbon pricing reduces emissions AI翻译
  作者：Sterner, Thomas
  作者单位：University of Gothenburg
  摘要：A meta-analysis of 21 carbon-pricing schemes suggests that the strategy reduces greenhouse-gas emissions. Deciding how high to set prices is the next step - and one that might benefit from the insights of less-aggregated studies in various sectors.
• What Kamala Harris's historic bid for the US presidency means for science AI翻译
  作者：Kozlov, Max; Lenharo, Mariana; Tollefson, Jeff
  摘要：The daughter of a scientist and a supporter of diversity in STEM, Harris as a potential candidate has stirred optimism among scientists.