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• A whole-brain single-cell atlas of circadian neural activity in mice AI翻译
  作者：Yamashita, Katsunari; Kinoshita, Fukuaki L.; Yoshida, Shota Y.; Matsumoto, Katsuhiko; Mitani, Tomoki T.; Fujishima, Hiroshi; Minami, Yoichi; Morii, Eiichi; Yamada, Rikuhiro G.; Okada, Seiji; Ueda, Hiroki R.
  作者单位：RIKEN; University of Tokyo; University of Osaka; University of Osaka; University of Osaka; University of Osaka; University of Tokyo; Niigata University; Kurume University
  摘要：The mammalian brain comprises numerous anatomical regions with distinct functions despite their extensive connectivity. How spontaneous neural activity is coordinated across regions over the circadian cycle remains elusive. We used tissue clearing and whole-brain c-Fos immunostaining on 144 mouse brains collected over 2 days under constant darkness. Time-series analysis revealed brainwide circadian rhythmicity at single-cell resolution, with 79% of the 642 anatomically defined regions oscillat...
• Disappearance of a massive star in the Andromeda Galaxy due to formation of a black hole AI翻译
  作者：De, Kishalay; Macleod, Morgan; Jencson, Jacob E.; Lovegrove, Elizabeth; Antoni, Andrea; Kara, Erin; Kasliwal, Mansi M.; Lau, Ryan M.; Loeb, Abraham; Masterson, Megan; Meisner, Aaron M.; Panagiotou, Christos; Quataert, Eliot; Simcoe, Robert
  作者单位：Columbia University; Columbia University; Simons Foundation; Flatiron Institute; Massachusetts Institute of Technology (MIT); California Institute of Technology; California Institute of Technology; National Science Foundation (NSF); Harvard University; Princeton University
  摘要：When a massive star reaches the end of its lifetime, its core collapses and releases neutrinos that drive a shock into the outer layers (the stellar envelope). A sufficiently strong shock ejects the envelope, producing a supernova. If the shock fails to eject it, the envelope is predicted to fall back onto the collapsing core, producing a stellar-mass black hole (BH) and causing the star to disappear. We report observations of M31-2014-DS1, a hydrogen-depleted supergiant in the Andromeda Galax...
• Biological data governance in an age of AI AI翻译
  作者：Bloomfield, Doni; Black, James R. M.; Crook, Oliver; Brandes, Nadav; Hanke, Moritz S.; Inglesby, Thomas V.; Cicero, Anita; Pollack, Robert; Hernandez-Boussard, Tina; Imperiale, Michael J.; Altman, Russ B.; Pannu, Jaspreet
  作者单位：Fordham University; Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health; University of Oxford; University of Oxford; Columbia University; Stanford University; Stanford University; University of Michigan System; University of Michigan; Stanford University; Stanford University; Stanford Medicine
• Learning to leave home AI翻译
  作者：Karina, Aigerim
  作者单位：Stockholm University
• 撤稿声明: Integrative phylogenomics positions sponges at the root of the animal tree AI翻译
  作者：Thorp, H. Holden
• Continental mantle earthquakes of the world (Publication with Expression of Concern. See vol. 392, 2026) AI翻译
  作者：Wang, Shiqi; Klemperer, Simon L.
  作者单位：Stanford University
  摘要：Continental mantle earthquakes (CMEs) and their implications for the rheological structure of continents have fascinated geophysicists for more than half a century. Existence of these earthquakes is no longer debated, but their identification remains sparse across the globe. Comparing the Sn and Lg seismic wave amplitude ratio (Sn/Lg) of an earthquake with that of nearby earthquakes distinguishes CMEs and, unlike previous methods, can be applied globally. We present a global distribution of CM...
• Progressive eastward rupture of the Main Marmara fault toward Istanbul AI翻译
  作者：Martinez-Garzon, Patricia C.; Chen, Xiang; Becker, Dirk; Nunez-Jara, Sebastian; Kartal, Recai Feyiz; Turker, Elif; Dresen, Georg; Ben-Zion, Yehuda; Jara, Jorge; Cotton, Fabrice; Kadirioglu, Filiz Tuba; Kilic, Tugbay; Bohnhoff, Marco
  作者单位：Helmholtz Association; GFZ Helmholtz Centre for Geosciences; RWTH Aachen University; Ruhr University Bochum; University of Hamburg; Prime Ministry Turkey; University of Potsdam; University of Southern California; Free University of Berlin
• A sudden change and recovery in the magnetic environment around a repeating fast radio burst AI翻译
  作者：Li, Y.; Zhang, S. B.; Yang, Y. P.; Tsai, C. W.; Yang, X.; Law, C. J.; Anna-Thomas, R.; Chen, X. L.; Lee, K. J.; Tang, Z. F.; Xiao, D.; Xu, H.; Yang, X. L.; Chen, G.; Feng, Y.; Li, D. Z.; Mckinven, R.; Niu, J. R.; Shin, K.; Wang, B. J.; Zhang, C. F.; Zhang, Y. K.; Zhou, D. J.; Zhu, Y. H.; Dai, Z. G.; Chang, C. M.; Geng, J. J.; Han, J. L.; Hu, L.; Li, D.; Luo, R.; Niu, C. H.; Shi, D. D.; Sun, T. R.; Wu, X. F.; Zhu, W. W.; Jiang, P.; Zhang, B.
  作者单位：Chinese Academy of Sciences; Purple Mountain Observatory, CAS; Nanjing Institute of Astronomical Optics & Technology, NAOC, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Commonwealth Scientific & Industrial Research Organisation (CSIRO); Australia Telescope National Facility; Yunnan University; Chinese Academy of Sciences; Nanjing Institute of Geology & Paleontology, CAS; National Astronomical Observatory, CAS; Beijing Normal University; California Institute of Technology; California Institute of Technology; West Virginia University; West Virginia University; University of Amsterdam; Peking University; Peking University; Chinese Academy of Sciences; Shanghai Astronomical Observatory, CAS; Zhejiang Laboratory; Zhejiang University; Princeton University; Tsinghua University; McGill University; McGill University; Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); Chinese Academy of Sciences; National Time Service Center, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; University of Pennsylvania; Carnegie Mellon University; Tsinghua University; Guangzhou University; Anhui University of Science & Technology; Guizhou University; University of Hong Kong; University of Hong Kong; Nevada System of Higher Education (NSHE); University of Nevada Las Vegas; Nevada System of Higher Education (NSHE); University of Nevada Las Vegas
  摘要：Fast radio bursts (FRBs) are millisecond-duration radio transients from extragalactic sources. Some repeating FRBs exhibit variations in their Faraday rotation measure (RM) due to changes in their magneto-ionic environment. We report magneto-ionic variations of FRB 20220529, a repeating FRB from a disk galaxy at redshift 0.18. For the first 17 months of observations, the RM had a median of 17 radians per square meter (rad m-2) and a scatter of 101 rad m-2. In December 2023, the RM jumped to 19...
• Deep contrastive learning enables genome-wide virtual screening AI翻译
  作者：Jia, Yinjun; Gao, Bowen; Tan, Jiaxin; Zheng, Jiqing; Hong, Xin; Zhu, Wenyu; Tan, Haichuan; Xiao, Yuan; Tan, Liping; Cai, Hongyi; Huang, Yanwen; Deng, Zhiheng; Wu, Xiangwei; Jin, Yue; Yuan, Yafei; Tian, Jiekang; He, Wei; Ma, Weiying; Zhang, Yaqin; Liu, Lei; Yan, Chuangye; Zhang, Wei; Lan, Yanyan
  作者单位：Tsinghua University; Tsinghua University; Tsinghua University; Tsinghua University; Tsinghua University; Tsinghua University; Tsinghua University; Tsinghua University; Tsinghua University; Peking University; Tsinghua University; Beijing Academy of Artificial Intelligence
  摘要：Recent breakthroughs in protein structure prediction have opened new avenues for genome-wide drug discovery, yet existing virtual screening methods remain computationally prohibitive. We present DrugCLIP, a contrastive learning framework that achieves ultrafast and accurate virtual screening, up to 10 million times faster than docking, while consistently outperforming various baselines on in silico benchmarks. In wet-lab validations, DrugCLIP achieved a 15% hit rate for norepinephrine transpor...
• Invasion impacts in terrestrial ecosystems: Global patterns and predictors (vol 390, pg 381, 2025) AI翻译
  作者：Thakur, M. P.