Science

最新文章

• Giant croc family tree revised AI翻译
  作者：Servick, Kelly
• Blood pressure and dementia AI翻译
  作者：Servick, Kelly
• Emergence and interstate spread of highly pathogenic avian influenza A(H5N1) in dairy cattle in the United States AI翻译
  作者：Thao-Quyen Nguyen; Hutter, Carl R.; Markin, Alexey; Thomas, Megan; Lantz, Kristina; Killian, Mary Lea; Janzen, Garrett M.; Vijendran, Sriram; Wagle, Sanket; Inderski, Blake; Magstadt, Drew R.; Li, Ganwu; Diel, Diego G.; Frye, Elisha Anna; Dimitrov, Kiril M.; Swinford, Amy K.; Thompson, Alexis C.; Snekvik, Kevin R.; Suarez, David L.; Lakin, Steven M.; Schwabenlander, Stacey; Ahola, Sara C.; Johnson, Kammy R.; Baker, Amy L.; Robbe-Austerman, Suelee; Torchetti, Mia Kim; Anderson, Tavis K.
  作者单位：United States Department of Agriculture (USDA); USDA Agricultural Research Service; Iowa State University; United States Department of Agriculture (USDA); USDA Agricultural Research Service; Iowa State University; Iowa State University; Cornell University; Texas A&M University System; Texas A&M University College Station; Washington State University; Washington State University; United States Department of Agriculture (USDA); USDA Agricultural Research Service
  摘要：Highly pathogenic avian influenza (HPAI) viruses cross species barriers and have the potential to cause pandemics. In North America, HPAI A(H5N1) viruses related to the goose/Guangdong 2.3.4.4b hemagglutinin phylogenetic clade have infected wild birds, poultry, and mammals. Our genomic analysis and epidemiological investigation showed that a reassortment event in wild bird populations preceded a single wild bird-to-cattle transmission episode. The movement of asymptomatic or presymptomatic cat...
• Rallying for US science AI翻译
  作者：Yanai, Itai
  作者单位：New York University
• Ultrafast aqueous electric double layer dynamics AI翻译
  作者：Greco, Alessandro; Imoto, Sho; Backus, Ellen H. G.; Nagata, Yuki; Hunger, Johannes; Bonn, Mischa
  作者单位：Max Planck Society; University of Vienna
  摘要：The electric double layer (EDL) is critical in electrochemical capacitors and transistors, on-water chemistry, and bioelectric technologies. Ion dynamics within the EDL define the limits for charging and discharging processes. Classical EDL models struggle at high electrolyte concentrations, and observing EDL dynamics has been challenging. In this study, an all-optical technique allowed real-time monitoring of EDL dynamics at arbitrary concentration by quasi-instantaneously changing the surfac...
• Healing waters AI翻译
  作者：Hughes, Jasmine Gabriel
  作者单位：University of Cambridge
• Structural basis for strychnine activation of human bitter taste receptor TAS2R46 ( vol 388 , 10.1126/science.adx9419 , 2025) AI翻译
  作者：Xu, Weixiu; Wu, Lijie; Liu, Shenhui; Liu, Xiao; Zhou, Cui; Zhang, Jinyi; Fu, You; Guo, Yu; Wu, Yiran; Tan, Qiwen; Wang, Ling; Liu, Junlin; Jiang, Longquan; Fan, Zhongbo; Pei, Yuan; Yu, Jingyi; Cheng, Jianjun; Zhao, Suwen; Hao, Xiaojiang; Liu, Zhi-Jie; Hua, Tian
• Governance can't be automated AI翻译
  作者：Stilgoe, Jack
  作者单位：University of London; University College London
• Structural basis for nucleolin recognition of MYC promoter G-quadruplex AI翻译
  作者：Chen, Luying; Dickerhoff, Jonathan; Zheng, Ke-wei; Erramilli, Satchal; Feng, Hanqiao; Wu, Guanhui; Onel, Buket; Chen, Yuwei; Wang, Kai-Bo; Carver, Megan; Lin, Clement; Sakai, Saburo; Wan, Jun; Vinson, Charles; Hurley, Laurence; Kossiakoff, Anthony A.; Deng, Nanjie; Bai, Yawen; Noinaj, Nicholas; Yang, Danzhou
  作者单位：Purdue University System; Purdue University; Hunan University; University of Chicago; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI); University of Arizona; Indiana University System; Indiana University Bloomington; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI); Pace University; Purdue University System; Purdue University; Purdue University System; Purdue University; Purdue University System; Purdue University
  摘要：The MYC oncogene promoter G-quadruplex (MycG4) regulates transcription and is a prevalent G4 locus in immortal cells. Nucleolin, a major MycG4-binding protein, exhibits greater affinity for MycG4 than for nucleolin recognition element (NRE) RNA. Nucleolin's four RNA binding domains (RBDs) are essential for high-affinity MycG4 binding. We present the 2.6-angstrom crystal structure of the nucleolin-MycG4 complex, revealing a folded parallel three-tetrad G-quadruplex with two coordinating potassi...
• Global soil pollution by toxic metals threatens agriculture and human health AI翻译
  作者：Hou, Deyi; Jia, Xiyue; Wang, Liuwei; McGrath, Steve P.; Zhu, Yong-Guan; Hu, Qing; Zhao, Fang-Jie; Bank, Michael S.; O'Connor, David; Nriagu, Jerome
  作者单位：Tsinghua University; Tsinghua University; UK Research & Innovation (UKRI); Biotechnology and Biological Sciences Research Council (BBSRC); Rothamsted Research; Chinese Academy of Sciences; Research Center for Eco-Environmental Sciences (RCEES), CAS; Chinese Academy of Sciences; Institute of Urban Environment, CAS; Southern University of Science & Technology; Nanjing Agricultural University; Institute of Marine Research - Norway; University of Massachusetts System; University of Massachusetts Amherst; Royal Agricultural University; University of Michigan System; University of Michigan
  摘要：Toxic metal pollution is ubiquitous in soils, yet its worldwide distribution is unknown. We analyzed a global database of soil pollution by arsenic, cadmium, cobalt, chromium, copper, nickel, and lead at 796,084 sampling points from 1493 regional studies and used machine learning techniques to map areas with exceedance of agricultural and human health thresholds. We reveal a previously unrecognized high-risk, metal-enriched zone in low-latitude Eurasia, which is attributed to influential clima...