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作者:Milner, William R.; Lannig, Stefan; Mamaev, Mikhail; Yan, Lingfeng; Chu, Anjun; Lewis, Ben; Frankel, Max N.; Hutson, Ross B.; Rey, Ana Maria; Ye, Jun
作者单位:University of Colorado System; University of Colorado Boulder; National Institute of Standards & Technology (NIST) - USA; University of Colorado System; University of Colorado Boulder
摘要:Scaling up the performance of atomic clocks requires understanding complex many-body Hamiltonians to ensure meaningful gains for metrological applications. Here we use a degenerate Fermi gas loaded into a three-dimensional optical lattice to study the effect of a tunable Fermi-Hubbard Hamiltonian. The clock laser introduces a spin-orbit coupling spiral phase and breaks the isotropy of superexchange interactions, leading to XXZ-type spin anisotropy. By tuning the lattice confinement and applyin...
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作者:Normile, Dennis
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作者:Jeon, Yong Geun; Kim, Jae Bum
作者单位:Seoul National University (SNU)
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作者:Chiu, David Kung-Chun; Zhang, Xiangyue; Cheng, Bowie Yik-Ling; Liu, Qiang; Hayashi, Kazukuni; Yu, Bo; Lee, Ryan; Zhang, Catherine; An, Xiuli; Rajadas, Jayakumar; Reticker-Flynn, Nathan E.; Rankin, Erinn B.; Engleman, Edgar G.
作者单位:Stanford University; Stanford University; Stanford University; New York Blood Center; Stanford University; Stanford University; Stanford University; Stanford Cancer Institute
摘要:Successful cancer immunotherapy requires a patient to mount an effective immune response against tumors; however, many cancers evade the body's immune system. To investigate the basis for treatment failure, we examined spontaneous mouse models of hepatocellular carcinoma (HCC) with either an inflamed T cell-rich or a noninflamed T cell-deprived tumor microenvironment (TME). Our studies reveal that erythropoietin (EPO) secreted by tumor cells determines tumor immunotype. Tumor-derived EPO auton...
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作者:Rubinoff, Daniel; San Jose, Michael; Doorenweerd, Camiel
作者单位:University of Hawaii System; University of Hawaii Manoa
摘要:Lepidoptera is the most herbivorous of all the insect orders, with predatory caterpillars globally comprising less than 0.13% of the nearly 200,000 moth and butterfly species. Here, we report a species in which caterpillars are carnivorous inhabitants of spider's webs, feeding on the arthropods that they find there. This Hawaiian lineage also boasts an unprecedented and macabre practice of decorating its portable larval home with the body parts of the spider prey it harvests from the web where...
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作者:Servick, Kelly
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作者:Wang, Guan; Li, Gaoyan; Song, Anying; Zhao, Yutian; Yu, Jiayu; Wang, Yifan; Dai, Wenting; Salas, Martha; Qin, Hanjun; Medrano, Leonard; Dow, Joan; Li, Aimin; Armstrong, Brian; Fueger, Patrick T.; Yu, Hua; Zhu, Yi; Shao, Mengle; Wu, Xiwei; Jiang, Lei; Campisi, Judith; Yang, Xia; Wang, Qiong A.
作者单位:City of Hope; University of California System; University of California Los Angeles; City of Hope; City of Hope; City of Hope; City of Hope; City of Hope; City of Hope; Beckman Research Institute of City of Hope; Baylor College of Medicine; Chinese Academy of Sciences; Shanghai Institute of Immunity and Infection, CAS; Buck Institute for Research on Aging; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles
摘要:Starting at middle age, adults often suffer from visceral adiposity and associated adverse metabolic disorders. Lineage tracing in mice revealed that adipose progenitor cells (APCs) in visceral fat undergo extensive adipogenesis during middle age. Thus, despite the low turnover rate of adipocytes in young adults, adipogenesis is unlocked during middle age. Transplantations quantitatively showed that APCs in middle-aged mice exhibited high adipogenic capacity cell-autonomously. Single-cell RNA ...
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作者:Ah-King, Malin
作者单位:Orebro University; Orebro University
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作者:Ghosh, Koushik
作者单位:United States Department of Energy (DOE); Sandia National Laboratories
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作者:Furnas, Alexander C.; LaPira, Timothy M.; Wang, Dashun
作者单位:Northwestern University; Northwestern University; Northwestern University; Northwestern University; James Madison University; Northwestern University