Science

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• GLOBAL HEALTH World agrees on pandemic treaty-without the US AI翻译
  作者：Kupferschmidt, Kai
• Structural mechanism of LINE-1 target-primed reverse transcription AI翻译
  作者：Ghanim, George E.; Hu, Hongmiao; Boulanger, Jerome; Thi Hoang Duong Nguyen
  作者单位：MRC Laboratory Molecular Biology
  摘要：Long interspersed element-1 (LINE-1) retrotransposons are the only active autonomous transposable elements in humans. They propagate by reverse transcribing their messenger RNA into new genomic locations by a process called target-primed reverse transcription (TPRT). In this work, we present four cryo-electron microscopy structures of the human LINE-1 TPRT complex, revealing the conformational dynamics of open reading frame 2 protein (ORF2p) and its extensive remodeling of the target DNA for T...
• Aluminum distribution and active site locations in the structures of zeolite ZSM-5 catalysts AI翻译
  作者：Rzepka, Przemyslaw; Huthwelker, Thomas; Dedecek, Jiri; Tabor, Edyta; Bernauer, Milan; Sklenak, Stepan; Mlekodaj, Kinga; van Bokhoven, Jeroen A.
  作者单位：Czech Academy of Sciences; J. Heyrovsky Institute of Physical Chemistry of the Czech Academy of Sciences; Swiss Federal Institutes of Technology Domain; ETH Zurich; Swiss Federal Institutes of Technology Domain; Paul Scherrer Institute; Swiss Federal Institutes of Technology Domain; Paul Scherrer Institute; University of Chemistry & Technology, Prague
  摘要：Zeolites have exceptional catalytic performance in oil refining and chemical synthesis that can be attributed to their well-defined porous structures that host active sites. This study pinpoints the exact locations of aluminum atoms in ZSM-5 structures-a key zeolite catalyst. Aluminum siting governs catalytic efficiency in acid and redox processes. Anomalous x-ray powder diffraction (AXRPD) at the aluminum K-edge probes the long-range order of aluminum atoms within the ZSM-5 frameworks, precis...
• Epo-calypse now AI翻译
  作者：Arnouk, Sana M.; Van Ginderachter, Jo A.
  作者单位：Vrije Universiteit Brussel; Flanders Institute for Biotechnology (VIB)
• Observation of generalized t-J spin dynamics with tunable dipolar interactions AI翻译
  作者：Carroll, Annette N.; Hirzler, Henrik; Miller, Calder; Wellnitz, David; Muleady, Sean R.; Lin, Junyu; Zamarski, Krzysztof P.; Wang, Reuben R. W.; Bohn, John L.; Rey, Ana Maria; Ye, Jun
  作者单位：University of Colorado System; University of Colorado Boulder; National Institute of Standards & Technology (NIST) - USA; National Institute of Standards & Technology (NIST) - USA; University System of Maryland; University of Maryland College Park; University of Innsbruck; Swiss Federal Institutes of Technology Domain; ETH Zurich; Smithsonian Institution; Harvard University
  摘要：Long-range and anisotropic dipolar interactions profoundly modify the dynamics of particles hopping in a periodic lattice potential. We report the realization of a generalized t-J model with dipolar interactions using a system of ultracold fermionic molecules with spin encoded in the two lowest rotational states. We independently tuned the dipolar Ising and spin-exchange couplings and the molecular motion and studied their interplay on coherent spin dynamics. Using Ramsey spectroscopy, we obse...
• US scientists must stand together AI翻译
  作者：Simha, Anita; Kandlikar, Gaurav
  作者单位：Louisiana State University System; Louisiana State University
• So Very Small: How Humans Discovered the Microcosmos, Defeated Germs-and May Still Lose the War Against Infectious Disease AI翻译
  作者：Smith, Tara C.
  作者单位：University System of Ohio; Kent State University; Kent State University Kent; Kent State University Salem
• Convergence and consensus AI翻译
  作者：Thorp, H. Holden
• Science, not silence: Save US economic growth AI翻译
  作者：Phillips, Philip
  作者单位：University of Illinois System; University of Illinois Urbana-Champaign; University of Illinois System; University of Illinois Urbana-Champaign
• Polyoxometalated metal-organic framework superstructure for stable water oxidation AI翻译
  作者：Yue, Kaihang; Lu, Ruihu; Gao, Mingbin; Song, Fei; Dai, Yao; Xia, Chenfeng; Mei, Bingbao; Dong, Hongliang; Qi, Ruijuan; Zhang, Daliang; Zhang, Jiangwei; Wang, Ziyun; Huang, Fuqiang; Xia, Bao Yu; Yan, Ya
  作者单位：Chinese Academy of Sciences; Shanghai Institute of Ceramics, CAS; Huazhong University of Science & Technology; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; University of Auckland; Chinese Academy of Sciences; Dalian Institute of Chemical Physics, CAS; Chinese Academy of Sciences; Shanghai Advanced Research Institute, CAS; East China Normal University; Chongqing University; Chongqing University; Inner Mongolia University; Shanghai Jiao Tong University; Sungkyunkwan University (SKKU)
  摘要：Stable, nonprecious catalysts are vital for large-scale alkaline water electrolysis. Here, we report a grafted superstructure, MOF@POM, formed by self-assembling a metal-organic framework (MOF) with polyoxometalate (POM). In situ electrochemical transformation converts MOF into active metal (oxy)hydroxides to produce a catalyst with a low overpotential of 178 millivolts at 10 milliamperes per square centimeter in alkaline electrolyte. An anion exchange membrane water electrolyzer incorporating...